product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
ZO-1; tight junction protein 1
catalog :
R26.4C
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
R26.4C
reactivity :
mouse, rat, dogs, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
more info or order :
citations: 39
Published Application/Species/Sample/Dilution | Reference |
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Tran J, Zheng X, Zheng Y. Lamin-B1 contributes to the proper timing of epicardial cell migration and function during embryonic heart development. Mol Biol Cell. 2016;27:3956-3963 pubmed
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Hernandez S, Chavez Munguia B, Gonzalez Mariscal L. ZO-2 silencing in epithelial cells perturbs the gate and fence function of tight junctions and leads to an atypical monolayer architecture. Exp Cell Res. 2007;313:1533-47 pubmed
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Tumbarello D, Turner C. Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway. J Cell Physiol. 2007;211:736-47 pubmed
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Chen H, Tung Y, Li B, Iqbal K, Grundke Iqbal I. Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol Aging. 2007;28:1148-62 pubmed
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Swetloff A, Greenwood S, Wade A, Ferretti P. Growth of choroid plexus epithelium vesicles in vitro depends on secretory activity. J Cell Physiol. 2006;208:549-55 pubmed
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Villanueva S, Cespedes C, Vio C. Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins. Am J Physiol Regul Integr Comp Physiol. 2006;290:R861-70 pubmed
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Gresh L, Bourachot B, Reimann A, Guigas B, Fiette L, Garbay S, et al. The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation. EMBO J. 2005;24:3313-24 pubmed
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Wagner M, Blazer Yost B, Boyd White J, Srirangam A, Pennington J, Bennett S. Expression of the unconventional myosin Myo1c alters sodium transport in M1 collecting duct cells. Am J Physiol Cell Physiol. 2005;289:C120-9 pubmed
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Talbott J, Loy D, Liu Y, Qiu M, Bunge M, Rao M, et al. Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol. 2005;192:11-24 pubmed
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Mendoza Rodriguez C, Gonzalez Mariscal L, Cerbón M. Changes in the distribution of ZO-1, occludin, and claudins in the rat uterine epithelium during the estrous cycle. Cell Tissue Res. 2005;319:315-30 pubmed
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Oshima R, Lesperance J, Munoz V, Hebbard L, Ranscht B, Sharan N, et al. Angiogenic acceleration of Neu induced mammary tumor progression and metastasis. Cancer Res. 2004;64:169-79 pubmed
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Brook G, Lawrence J, Shah B, Raisman G. Extrusion transplantation of Schwann cells into the adult rat thalamus induces directional host axon growth. Exp Neurol. 1994;126:31-43 pubmed
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Stevenson B, Siliciano J, Mooseker M, Goodenough D. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol. 1986;103:755-66 pubmed
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Anderson J, Stevenson B, Jesaitis L, Goodenough D, Mooseker M. Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. J Cell Biol. 1988;106:1141-9 pubmed
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product information
Internal ID :
3490
Name :
R26.4C
Depositor Name :
Goodenough, D.A.
Depositor Institution :
Harvard Medical School
Date Deposited :
3/29/89
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
ZO-1; tight junction protein 1
Antigen Species :
Mouse
Host Species :
rat
Isotype :
RIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Canine,Fish,Mouse,Porcine,Rat,Zebrafish
Species Tested (legacy) :
positive: rat, mouse, dog, pig; negative: human
Initial Publication Pubmed ID :
3528172
Depositor Notes (Special Instructions) :
The epitope bound by this antibody is on the cytoplasmic face of plasma membrane at tight junctions.
Collections :
Cell signaling
Search Keywords :
Goodenough, Daniel A., ZO-1 tight junction protein, Mouse, RIgG1, kappa light chain, Rat/Mouse/Canine/Porcine/Zebrafish, Tjp1, Zo1, AB_2205518, monoclonal, Tjp-1
Antigen Molecular Weight :
194kD Predicted; 225k kD on SDS-PAGE
Gene :
Tjp1
Alternate Gene Name(s) :
Zo1
Uniprot ID :
F1M4A0
Antibody Registry ID :
AB_2205518
Immunogen :
Isolated deoxycholate-extracted plasma membrane junctional regions from liver
Clonality :
Monoclonal
Myeloma Strain :
P3x63 Ag8U.1 (CRL 1597)
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
24603700 24089482 3528172 20556794 23813953 22121117 17237226 16138077 15716323 16741962 16284088 15558325 18327767 17374535 8157125 31414384
Immunofluorescence Pubmed IDs :
24205179 23813953 17299801 31326655
Western Blot Pubmed IDs :
2452168 3528172 23813953
Immunoprecipitation Pubmed IDs :
23813953
FFPE Pubmed IDs :
16284088 14729621 22121117
Pubmed IDs :
16859812 15698615
DSHB Growth Medium :
RPMI
References (legacy) :
J. Cell Biol. 103, 755-766.; J. Cell Biol. 106, 1141-1149.
more info or order :
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Developmental Studies Hybridoma Bank
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