catenin, beta- (MIgM) | Developmental Studies Hybridoma Bank PY654-B-catenin product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

catenin, beta- (MIgM)

catalog :

PY654-B-catenin

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

PY654-B-catenin

reactivity :

mouse, chicken

application :

western blot, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 1

Reference
Rhee J, Buchan T, Zukerberg L, Lilien J, Balsamo J. Cables links Robo-bound Abl kinase to N-cadherin-bound beta-catenin to mediate Slit-induced modulation of adhesion and transcription. Nat Cell Biol. 2007;9:883-92 pubmed

product information

Internal ID :

561

Name :

PY654-B-catenin

Depositor Name :

Balsamo, J. / Lilien, J.

Depositor Institution :

University of Iowa

Date Deposited :

8/11/06

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

catenin, beta- (MIgM)

Antigen Species :

mouse

Host Species :

mouse

Isotype :

MIgM

Isotype for catalog (legacy) :

IgM

Positive Tested Species Reactivity :

Chicken,Mouse

Species Tested (legacy) :

mouse, chicken

Initial Publication Pubmed ID :

17618275

Collections :

Cell adhesion,Cell signaling,Transcription factors

Search Keywords :

Balsamo, J. / Lilien, J., catenin, beta- (MIgM), mouse, MIgM, mouse/chicken, Ctnnb1, Bfc; Mesc; Catnb, AB_10144656, monoclonal, Cell adhesion/Cell signaling/Transcription factors, Immunofluorescence/Western Blot

Antigen Molecular Weight :

Predicted: 85 kDa

Gene :

Ctnnb1

Alternate Gene Name(s) :

Bfc; Mesc; Catnb

Uniprot ID :

Q02248

Antibody Registry ID :

AB_10144656

Synonyms (Alternate Clone Names) :

PY654

Immunogen :

syntetic phospho-peptide

Immunogen Sequence :

NH2-CELLHSRNEGVATpYAA-OH

Clonality :

Monoclonal

Myeloma Strain :

SP2/0

Epitope Mapped :

Yes

Epitope Location or Sequence :

NH2-CELLHSRNEGVATpYAA-OH

Epitope Map PubMed ID :

17618275

Recommended Applications :

Immunofluorescence,Western Blot

Immunoblotting (legacy) :

Yes

Immunofluorescence Pubmed IDs :

17618275

Western Blot Pubmed IDs :

17618275

Additional Information :

This antibody is specific to beta-catenin phosphorylated at Tyr 654. Beta-1 Catenin is a Key downstream component of the canonical Wnt signaling pathway whose function is affected by differential phosphorylation. Specificity tested on Y654F beta-catenin. See mAb PY489-B-catenin for an antibody specific to beta-catenin phosphorylated at Tyr 489. The catenin target of PY489-B-catenin has been described as nuclear-bound, and the target of PY654-B-catenin has been described as membrane-bound/cytoplasmic [PMID 25367124].

DSHB Growth Medium :

Iscove's

References (legacy) :

Nat. Cell Biol. 9(8), 883-892.

more info or order :

Developmental Studies Hybridoma Bank product webpage