product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Pax7
catalog :
PAX7
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PAX7
reactivity :
Spanish newt, dime-store turtle, degu, Japanese common newt, human, mouse, rat, dogs, chicken, zebrafish , Xenopus laevis
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, chromatin immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, immunohistochemistry knockout validation
citations: 330
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:50; loading ...; fig 3a
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 3a
Chen X, Yuan J, Xue G, Campanario S, Wang D, Wang W, et al. Translational control by DHX36 binding to 5'UTR G-quadruplex is essential for muscle stem-cell regenerative functions. Nat Commun. 2021;12:5043 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10; loading ...; fig s3a
Kurosaka M, Ogura Y, Sato S, Kohda K, Funabashi T. Transcription factor signal transducer and activator of transcription 6 (STAT6) is an inhibitory factor for adult myogenesis. Skelet Muscle. 2021;11:14 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1g
Zhou S, Zhang W, Cai G, Ding Y, Wei C, Li S, et al. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration. Cell Res. 2020;30:1063-1077 pubmed publisher
  • immunocytochemistry; human; 1:10; loading ...; fig 2b
Barruet E, Garcia S, Striedinger K, Wu J, Lee S, Byrnes L, et al. Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 1b
Choi I, Lim H, Cho H, Oh Y, Chou B, Bai H, et al. Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10; loading ...; fig s4a
de Morrée A, Klein J, Gan Q, Farup J, Urtasun A, Kanugovi A, et al. Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science. 2019;366:734-738 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10; loading ...; fig 4e
Jia Z, Nie Y, Yue F, Kong Y, Gu L, Gavin T, et al. A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10; loading ...; fig s11c
Soldatov R, Kaucka M, Kastriti M, Petersen J, Chontorotzea T, Englmaier L, et al. Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019;364: pubmed publisher
  • immunohistochemistry - frozen section; degu; 1:1000; loading ...; fig 11
Deichler A, Carrasco D, González Cabrera C, Letelier J, Mar n G, Mpodozis J. The nucleus pretectalis principalis: A pretectal structure hidden in the mammalian thalamus. J Comp Neurol. 2019;527:372-391 pubmed publisher
  • immunocytochemistry; mouse; 1:40; loading ...; fig 2f
Baghdadi M, Firmino J, Soni K, Evano B, Di Girolamo D, Mourikis P, et al. Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence. Cell Stem Cell. 2018;23:859-868.e5 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:5-1:10; loading ...; fig 5a
Gallot Y, Straughn A, Bohnert K, Xiong G, Hindi S, Kumar A. MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice. Hum Mol Genet. 2018;27:3449-3463 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:20; loading ...; fig 1c
Alonso Martin S, Aurade F, Mademtzoglou D, Rochat A, Zammit P, Relaix F. SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity. elife. 2018;7: pubmed publisher
  • western blot; mouse; loading ...; fig 1b
de Morrée A, van Velthoven C, Gan Q, Salvi J, Klein J, Akimenko I, et al. Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence. Proc Natl Acad Sci U S A. 2017;114:E8996-E9005 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4c
Zhu X, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, et al. A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017;292:9409-9419 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 1
Mackey A, Magnan M, Chazaud B, Kjaer M. Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration. J Physiol. 2017;595:5115-5127 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10; loading ...; fig 4a
Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 12B
Shen C, Zhou J, Wang X, Yu X, Liang C, Liu B, et al. Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3? Signaling Pathway. EBioMedicine. 2017;16:238-250 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2A
  • western blot; mouse; loading ...; fig 4B; 5D
Nie Y, Chen H, Guo C, Yuan Z, Zhou X, Zhang Y, et al. Palmdelphin promotes myoblast differentiation and muscle regeneration. Sci Rep. 2017;7:41608 pubmed publisher
  • immunocytochemistry; mouse; 1:10; fig 1a
  • western blot; mouse; 1:50; fig 1c
Yue F, Bi P, Wang C, Shan T, Nie Y, Ratliff T, et al. Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nat Commun. 2017;8:14328 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 1c
Lala Tabbert N, AlSudais H, Marchildon F, Fu D, Wiper Bergeron N. CCAAT/enhancer binding protein β is required for satellite cell self-renewal. Skelet Muscle. 2016;6:40 pubmed
  • immunohistochemistry; human; 1:100; loading ...; fig 2b
McKenzie A, D Lugos A, Saunders M, Gworek K, Luden N. Fiber Type-Specific Satellite Cell Content in Cyclists Following Heavy Training with Carbohydrate and Carbohydrate-Protein Supplementation. Front Physiol. 2016;7:550 pubmed
  • immunohistochemistry; mouse
Ross J, Pearson A, Levy Y, Cardel B, Handschin C, Ochala J. Exploring the Role of PGC-1? in Defining Nuclear Organisation in Skeletal Muscle Fibres. J Cell Physiol. 2017;232:1270-1274 pubmed publisher
  • immunohistochemistry; mouse; 1:20-1:100; fig 3a
Knopp P, Krom Y, Banerji C, Panamarova M, Moyle L, den Hamer B, et al. DUX4 induces a transcriptome more characteristic of a less-differentiated cell state and inhibits myogenesis. J Cell Sci. 2016;129:3816-3831 pubmed
  • immunohistochemistry; mouse; fig 2
Southard S, Kim J, Low S, Tsika R, Lepper C. Myofiber-specific TEAD1 overexpression drives satellite cell hyperplasia and counters pathological effects of dystrophin deficiency. elife. 2016;5: pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...
Murach K, Walton R, Fry C, Michaelis S, Groshong J, Finlin B, et al. Cycle training modulates satellite cell and transcriptional responses to a bout of resistance exercise. Physiol Rep. 2016;4: pubmed publisher
  • immunohistochemistry; mouse; 1:25; loading ...; fig 2e
Xie X, Tsai S, Tsai M. COUP-TFII regulates satellite cell function and muscular dystrophy. J Clin Invest. 2016;126:3929-3941 pubmed publisher
  • immunohistochemistry - free floating section; Xenopus laevis; 1:500; loading ...; tbl 2
Morona R, Ferran J, Puelles L, González A. Gene expression analysis of developing cell groups in the pretectal region of Xenopus laevis. J Comp Neurol. 2017;525:715-752 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:5; loading ...; fig 1a
Egner I, Bruusgaard J, Gundersen K. Satellite cell depletion prevents fiber hypertrophy in skeletal muscle. Development. 2016;143:2898-906 pubmed publisher
  • immunocytochemistry; mouse; 1:20; loading ...; fig s1b
  • immunohistochemistry; mouse; 1:20; loading ...; fig s9b
Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
  • western blot; rat; 1:500; fig 1
Puchert M, Adams V, Linke A, Engele J. Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise. Cell Signal. 2016;28:1205-15 pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 2
Yao Y, Norris E, Mason C, Strickland S. Laminin regulates PDGFR?(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed publisher
  • immunocytochemistry; human; 1:250; fig s1
Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, et al. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nat Neurosci. 2016;19:807-15 pubmed publisher
  • immunohistochemistry - frozen section; Japanese common newt; 1:200; loading ...; fig 1g
Tanaka H, Ng N, Yang Yu Z, Casco Robles M, Maruo F, Tsonis P, et al. A developmentally regulated switch from stem cells to dedifferentiation for limb muscle regeneration in newts. Nat Commun. 2016;7:11069 pubmed publisher
  • immunocytochemistry; mouse; fig s11
Park S, Yun Y, Lim J, Kim M, Kim S, Kim J, et al. Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016;7:10871 pubmed publisher
  • western blot; human; 1:500; fig 4
Farini A, Sitzia C, Cassinelli L, Colleoni F, Parolini D, Giovanella U, et al. Inositol 1,4,5-trisphosphate (IP3)-dependent Ca2+ signaling mediates delayed myogenesis in Duchenne muscular dystrophy fetal muscle. Development. 2016;143:658-69 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10; fig 3
  • immunocytochemistry; mouse; 1:10; fig 5
  • western blot; mouse; 1:1000; fig 5
Ogura Y, Hindi S, Sato S, Xiong G, Akira S, Kumar A. TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair. Nat Commun. 2015;6:10123 pubmed publisher
  • immunohistochemistry; human; 1:50; fig 1
Hoeber J, Trolle C, König N, Du Z, Gallo A, Hermans E, et al. Human Embryonic Stem Cell-Derived Progenitors Assist Functional Sensory Axon Regeneration after Dorsal Root Avulsion Injury. Sci Rep. 2015;5:10666 pubmed publisher
  • immunohistochemistry; chicken; 1:20; fig s3i
Schock E, Chang C, Struve J, Chang Y, Chang J, Delany M, et al. Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome. Dis Model Mech. 2015;8:855-66 pubmed publisher
  • immunohistochemistry; zebrafish ; 1:100; fig 3
Solchenberger B, Russell C, Kremmer E, Haass C, Schmid B. Granulin knock out zebrafish lack frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis pathology. PLoS ONE. 2015;10:e0118956 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Feeney S, McGrath M, Sriratana A, Gehrig S, Lynch G, D Arcy C, et al. FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1). PLoS ONE. 2015;10:e0117665 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Labarge S, McDonald M, Smith Powell L, Auwerx J, Huss J. Estrogen-related receptor-? (ERR?) deficiency in skeletal muscle impairs regeneration in response to injury. FASEB J. 2014;28:1082-97 pubmed publisher
  • immunohistochemistry - free floating section; Spanish newt; 1:500
Joven A, Morona R, González A, Moreno N. Spatiotemporal patterns of Pax3, Pax6, and Pax7 expression in the developing brain of a urodele amphibian, Pleurodeles waltl. J Comp Neurol. 2013;521:3913-53 pubmed publisher
  • immunohistochemistry; rat
Przewoźniak M, Czaplicka I, Czerwinska A, Markowska Zagrajek A, Moraczewski J, Stremińska W, et al. Adhesion proteins--an impact on skeletal myoblast differentiation. PLoS ONE. 2013;8:e61760 pubmed publisher
  • immunohistochemistry - paraffin section; chicken; 1:100
Kobayashi N, Homma S, Okada T, Masuda T, Sato N, Nishiyama K, et al. Elucidation of target muscle and detailed development of dorsal motor neurons in chick embryo spinal cord. J Comp Neurol. 2013;521:2987-3002 pubmed publisher
  • western blot; rat
  • immunohistochemistry - free floating section; Spanish newt; 1:500
  • western blot; Spanish newt
Joven A, Morona R, González A, Moreno N. Expression patterns of Pax6 and Pax7 in the adult brain of a urodele amphibian, Pleurodeles waltl. J Comp Neurol. 2013;521:2088-124 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Criswell T, Corona B, Wang Z, Zhou Y, Niu G, Xu Y, et al. The role of endothelial cells in myofiber differentiation and the vascularization and innervation of bioengineered muscle tissue in vivo. Biomaterials. 2013;34:140-9 pubmed publisher
  • immunohistochemistry; dime-store turtle; 1:500
Moreno N, Dominguez L, Morona R, González A. Subdivisions of the turtle Pseudemys scripta hypothalamus based on the expression of regulatory genes and neuronal markers. J Comp Neurol. 2012;520:453-78 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:10
Vue T, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore J, Martin D, et al. Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007;505:73-91 pubmed
Ribeiro A, Souza L, Almeida C, Ishiba R, Fernandes S, Guerrieri D, et al. Muscle satellite cells and impaired late stage regeneration in different murine models for muscular dystrophies. Sci Rep. 2019;9:11842 pubmed publisher
Bronisz Budzynska I, Chwalenia K, Mucha O, Podkalicka P, Karolina Bukowska Strakova -, Jozkowicz A, et al. miR-146a deficiency does not aggravate muscular dystrophy in mdx mice. Skelet Muscle. 2019;9:22 pubmed publisher
Schroer A, Mohamed J, Willard M, Setola V, OESTREICH E, Siderovski D. A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation. PLoS ONE. 2019;14:e0216167 pubmed publisher
Chacon J, Rogers C. Early expression of Tubulin Beta-III in avian cranial neural crest cells. Gene Expr Patterns. 2019;34:119067 pubmed publisher
Muyskens J, Foote D, Bigot N, Strycker L, Smolkowski K, Kirkpatrick T, et al. Cellular and morphological changes with EAA supplementation before and after total knee arthroplasty. J Appl Physiol (1985). 2019;127:531-545 pubmed publisher
Su Y, Yu Y, Liu C, Zhang Y, Liu C, Ge M, et al. Fate decision of satellite cell differentiation and self-renewal by miR-31-IL34 axis. Cell Death Differ. 2019;: pubmed publisher
Englund D, Peck B, Murach K, Neal A, Caldwell H, McCarthy J, et al. Resident muscle stem cells are not required for testosterone-induced skeletal muscle hypertrophy. Am J Physiol Cell Physiol. 2019;317:C719-C724 pubmed publisher
Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi D, et al. Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress. Cell Stem Cell. 2019;24:944-957.e5 pubmed publisher
Ohno Y, Ando K, Ito T, Suda Y, Matsui Y, Oyama A, et al. Lactate Stimulates a Potential for Hypertrophy and Regeneration of Mouse Skeletal Muscle. Nutrients. 2019;11: pubmed publisher
Abe K, Shimada A, Tayama S, Nishikawa H, Kaneko T, Tsuda S, et al. Horizontal Boundary Cells, a Special Group of Somitic Cells, Play Crucial Roles in the Formation of Dorsoventral Compartments in Teleost Somite. Cell Rep. 2019;27:928-939.e4 pubmed publisher
Hutchins E, Bronner M. Draxin alters laminin organization during basement membrane remodeling to control cranial neural crest EMT. Dev Biol. 2019;446:151-158 pubmed publisher
Yao X, Yu T, Xi F, Xu Y, Ma L, Pan X, et al. BAMBI shuttling between cytosol and membrane is required for skeletal muscle development and regeneration. Biochem Biophys Res Commun. 2018;: pubmed publisher
Lagalice L, Pichon J, Gougeon E, Soussi S, Deniaud J, Ledevin M, et al. Satellite cells fail to contribute to muscle repair but are functional in Pompe disease (glycogenosis type II). Acta Neuropathol Commun. 2018;6:116 pubmed publisher
Sampath S, Sampath S, Ho A, Corbel S, Millstone J, Lamb J, et al. Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M. Nat Commun. 2018;9:1531 pubmed publisher
Nederveen J, Joanisse S, Snijders T, Thomas A, Kumbhare D, Parise G. The influence of capillarization on satellite cell pool expansion and activation following exercise-induced muscle damage in healthy young men. J Physiol. 2018;596:1063-1078 pubmed publisher
Tierney M, Stec M, Rulands S, Simons B, Sacco A. Muscle Stem Cells Exhibit Distinct Clonal Dynamics in Response to Tissue Repair and Homeostatic Aging. Cell Stem Cell. 2018;22:119-127.e3 pubmed publisher
Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, et al. The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017;8:e3173 pubmed publisher
Du H, Shih C, Wosczyna M, Mueller A, Cho J, Aggarwal A, et al. Macrophage-released ADAMTS1 promotes muscle stem cell activation. Nat Commun. 2017;8:669 pubmed publisher
Snouffer A, Brown D, Lee H, Walsh J, Lupu F, Norman R, et al. Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice. PLoS Genet. 2017;13:e1006912 pubmed publisher
Gao H, Hartnett S, Li Y. Ubiquitin C-Terminal Hydrolase L1 regulates myoblast proliferation and differentiation. Biochem Biophys Res Commun. 2017;492:96-102 pubmed publisher
Solanas G, Peixoto F, Perdiguero E, Jardi M, Ruiz Bonilla V, Datta D, et al. Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress. Cell. 2017;170:678-692.e20 pubmed publisher
Wang C, Li J, Meng Q, Wang B. Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse. Dev Biol. 2017;430:156-165 pubmed publisher
Perroud J, Bernheim L, Frieden M, Koenig S. Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. J Cell Sci. 2017;130:3083-3093 pubmed publisher
Thomas J, Sznajder Ł, Bardhi O, Aslam F, Anastasiadis Z, Scotti M, et al. Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy. Genes Dev. 2017;31:1122-1133 pubmed publisher
Monge C, DiStasio N, Rossi T, Sébastien M, Sakai H, Kalman B, et al. Quiescence of human muscle stem cells is favored by culture on natural biopolymeric films. Stem Cell Res Ther. 2017;8:104 pubmed publisher
Roellig D, Tan Cabugao J, Esaian S, Bronner M. Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells. elife. 2017;6: pubmed publisher
Miersch C, Stange K, Hering S, Kolisek M, Viergutz T, Röntgen M. Molecular and functional heterogeneity of early postnatal porcine satellite cell populations is associated with bioenergetic profile. Sci Rep. 2017;7:45052 pubmed publisher
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed publisher
Goh Q, Millay D. Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy. elife. 2017;6: pubmed publisher
Schwörer S, Becker F, Feller C, Baig A, Köber U, Henze H, et al. Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals. Nature. 2016;540:428-432 pubmed publisher
Paris N, Soroka A, Klose A, Liu W, Chakkalakal J. Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration. elife. 2016;5: pubmed publisher
Blanc R, Vogel G, Li X, Yu Z, Li S, Richard S. Arginine Methylation by PRMT1 Regulates Muscle Stem Cell Fate. Mol Cell Biol. 2017;37: pubmed publisher
Moyle L, Blanc E, Jaka O, Prueller J, Banerji C, Tedesco F, et al. Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. elife. 2016;5: pubmed publisher
Caprara G, Morabito C, Perni S, Navarra R, Guarnieri S, Mariggio M. Evidence for Altered Ca2+ Handling in Growth Associated Protein 43-Knockout Skeletal Muscle. Front Physiol. 2016;7:493 pubmed
Maesner C, Almada A, Wagers A. Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting. Skelet Muscle. 2016;6:35 pubmed publisher
Junge H, Yung A, Goodrich L, Chen Z. Netrin1/DCC signaling promotes neuronal migration in the dorsal spinal cord. Neural Dev. 2016;11:19 pubmed
Kivela R, Salmela I, Nguyen Y, Petrova T, Koistinen H, Wiener Z, et al. The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation. Nat Commun. 2016;7:13124 pubmed publisher
Nagahisa H, Mukai K, Ohmura H, Takahashi T, Miyata H. Effect of High-Intensity Training in Normobaric Hypoxia on Thoroughbred Skeletal Muscle. Oxid Med Cell Longev. 2016;2016:1535367 pubmed
Al Jaam B, Heu K, Pennarubia F, Segelle A, Magnol L, Germot A, et al. Reduced Notch signalling leads to postnatal skeletal muscle hypertrophy in Pofut1cax/cax mice. Open Biol. 2016;6: pubmed publisher
Czerwinska A, Nowacka J, Aszer M, Gawrzak S, Archacka K, Fogtman A, et al. Cell cycle regulation of embryonic stem cells and mouse embryonic fibroblasts lacking functional Pax7. Cell Cycle. 2016;15:2931-2942 pubmed
Chal J, Al Tanoury Z, Hestin M, Gobert B, Aivio S, Hick A, et al. Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro. Nat Protoc. 2016;11:1833-50 pubmed publisher
Costamagna D, Mommaerts H, Sampaolesi M, Tylzanowski P. Noggin inactivation affects the number and differentiation potential of muscle progenitor cells in vivo. Sci Rep. 2016;6:31949 pubmed publisher
Zhao Q, Kang Y, Wang H, Guan W, Li X, Jiang L, et al. Expression profiling and functional characterization of miR-192 throughout sheep skeletal muscle development. Sci Rep. 2016;6:30281 pubmed publisher
Sellathurai J, Nielsen J, Hejbøl E, Jørgensen L, Dhawan J, Nielsen M, et al. Low Oxygen Tension Enhances Expression of Myogenic Genes When Human Myoblasts Are Activated from G0 Arrest. PLoS ONE. 2016;11:e0158860 pubmed publisher
De Cristofaro T, Di Palma T, Soriano A, Monticelli A, Affinito O, Cocozza S, et al. Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma. Oncotarget. 2016;7:41929-41947 pubmed publisher
Mahmoud M, Kim H, Xing R, Hsiao S, Mammoto A, Chen J, et al. TWIST1 Integrates Endothelial Responses to Flow in Vascular Dysfunction and Atherosclerosis. Circ Res. 2016;119:450-62 pubmed publisher
Quarta M, Brett J, DiMarco R, de Morrée A, Boutet S, Chacon R, et al. An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy. Nat Biotechnol. 2016;34:752-9 pubmed publisher
Zhang R, Judson R, Liu D, Kast J, Rossi F. The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration. Skelet Muscle. 2016;6:22 pubmed publisher
Jensen L, Jørgensen L, Bech R, Frandsen U, Schrøder H. Skeletal Muscle Remodelling as a Function of Disease Progression in Amyotrophic Lateral Sclerosis. Biomed Res Int. 2016;2016:5930621 pubmed publisher
Jaafar Marican N, Cruz Migoni S, Borycki A. Asymmetric Distribution of Primary Cilia Allocates Satellite Cells for Self-Renewal. Stem Cell Reports. 2016;6:798-805 pubmed publisher
Pipalia T, Koth J, Roy S, Hammond C, Kawakami K, Hughes S. Cellular dynamics of regeneration reveals role of two distinct Pax7 stem cell populations in larval zebrafish muscle repair. Dis Model Mech. 2016;9:671-84 pubmed publisher
González N, Moresco J, Cabezas F, de la Vega E, Bustos F, Yates J, et al. Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors. PLoS ONE. 2016;11:e0154919 pubmed publisher
Kornegay J, Bogan D, Bogan J, Dow J, Wang J, Fan Z, et al. Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures. Skelet Muscle. 2016;6:14 pubmed publisher
Almeida C, Fernandes S, Ribeiro Junior A, Keith Okamoto O, Vainzof M. Muscle Satellite Cells: Exploring the Basic Biology to Rule Them. Stem Cells Int. 2016;2016:1078686 pubmed publisher
Davignon L, Chauveau C, Julien C, Dill C, Duband Goulet I, Cabet E, et al. The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease. Hum Mol Genet. 2016;25:1559-73 pubmed publisher
Faralli H, Wang C, Nakka K, Benyoucef A, Sebastian S, Zhuang L, et al. UTX demethylase activity is required for satellite cell-mediated muscle regeneration. J Clin Invest. 2016;126:1555-65 pubmed publisher
Morena D, Maestro N, Bersani F, Forni P, Lingua M, Foglizzo V, et al. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. elife. 2016;5: pubmed publisher
Marchildon F, Fu D, Lala Tabbert N, Wiper Bergeron N. CCAAT/enhancer binding protein beta protects muscle satellite cells from apoptosis after injury and in cancer cachexia. Cell Death Dis. 2016;7:e2109 pubmed publisher
Kim J, Hopkinson M, Kavishwar M, Fernandez Fuente M, Brown S. Prenatal muscle development in a mouse model for the secondary dystroglycanopathies. Skelet Muscle. 2016;6:3 pubmed publisher
Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed publisher
Malecova B, Dall Agnese A, Madaro L, Gatto S, Coutinho Toto P, Albini S, et al. TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. elife. 2016;5: pubmed publisher
Hwang O, Park J, Lee E, Lee E, Kim A, Jeong K. Therapeutic Effect of Losartan, an Angiotensin II Type 1 Receptor Antagonist, on CClâ‚„-Induced Skeletal Muscle Injury. Int J Mol Sci. 2016;17:227 pubmed publisher
Safdar A, Khrapko K, Flynn J, Saleem A, De Lisio M, Johnston A, et al. Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice. Skelet Muscle. 2016;6:7 pubmed publisher
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Kumar D, Shadrach J, Wagers A, Lassar A. Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells. Mol Biol Cell. 2009;20:3170-7 pubmed publisher
Moresi V, Garcia Alvarez G, Pristerá A, Rizzuto E, Albertini M, Rocchi M, et al. Modulation of caspase activity regulates skeletal muscle regeneration and function in response to vasopressin and tumor necrosis factor. PLoS ONE. 2009;4:e5570 pubmed publisher
Gnocchi V, White R, Ono Y, Ellis J, Zammit P. Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells. PLoS ONE. 2009;4:e5205 pubmed publisher
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product information
Internal ID :
2827
Name :
PAX7
Depositor Name :
Kawakami, A.
Depositor Institution :
Tokyo Institute of Technology
Date Deposited :
7/9/97
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Pax7
Antigen Species :
Chicken
Host Species :
mouse
Isotype :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Amphibian,Avian,Bovine,Canine,Fish,Goat,Human,Mouse,Ovine,Porcine,Rat,Turtle,Xenopus,Zebrafish
Species Tested (legacy) :
chicken, mouse, zebrafish, rat, human, axolotl, xenopus
Initial Publication Pubmed ID :
9376315
Depositor Notes (Special Instructions) :
This antibody recognizes a transcription factor in regulation of myogenesis.
Collections :
Cardiac development,Cell markers,Human,Skeletal muscle,Stem cell,Transcription factors,Xenopus
Search Keywords :
Kawakami, Atsushi, Pax7, Chicken, MIgG1, kappa light chain, Amphibian/Avian/Human/Mouse/Rat/Xenopus/Zebrafish/Turtle/Goat/Canine/Bovine/Ovine/Porcine/Fish, Pax7, PAX-7, AB_528428, Monoclonal
Antigen Molecular Weight :
Predicted: 57.5 kDa; Apparent: 50, 53 and 55 kDa
Gene :
Pax7
Alternate Gene Name(s) :
PAX-7
Uniprot ID :
O42349
Antibody Registry ID :
AB_528428
Immunogen :
Recombinant protein (C-terminal region, aa 352-523)
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
P3U1
Epitope Mapped :
Yes
Epitope Location or Sequence :
C-terminal region, aa 418-427
Epitope Map PubMed ID :
25133429
Recommended Applications :
Chromatin Immunoprecipitation,FACS,FFPE,Gel Supershift,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
24717807 24297751 23577150 23554995 23407937 23266330 23583585 21337346 20146251 17314134 17215296 16631154 30579765 8929535 31006621 31412923 30999708 30995487 31343947 31314585 31369820
Immunofluorescence Pubmed IDs :
23154418 23250359 23569214 23392112 23386031 23639729 25140675 24498167 24563216 24691550 26237517 27452271 27583644 28800946 28802040 29168801 30579765 26287727 29249462 29315567 25695429 25785851 29670077 27144531 27161363 27149989 26645687 30382921 30580997 31006621 31332295 31413358 31408461 31412923
Western Blot Pubmed IDs :
28803986 27144531 27161363 27149989 24763754 23505517 23114596 22764051 22661705 21680532 23110050 22322971 22434133 31332295
Immunoprecipitation Pubmed IDs :
22446594 15520282 16762317
Chromatin Immunoprecipitation Pubmed IDs :
16762317 18198279
FFPE Pubmed IDs :
17194759 22736793 25133429
FACS Pubmed IDs :
22403007
Gel Supershift Pubmed IDs :
19458195
Pubmed IDs :
25133429 24894000 23893976 23583585 21337346 20146251 17314134 17215296 16631154
Additional Information :
This antibody recognizes the nuclei in adult skeletal muscle satellite cells
DSHB Growth Medium :
Iscove's
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US