CD18 (integrin beta-2; beta subunit of CD11a, b, c), human | Developmental Studies Hybridoma Bank P4H9 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

CD18 (integrin beta-2; beta subunit of CD11a, b, c), human

catalog :

P4H9

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P4H9

reactivity :

human

application :

immunohistochemistry, FACS

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 2

Reference
Dittel B, McCarthy J, Wayner E, LeBien T. Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1). Blood. 1993;81:2272-82 pubmed
Languino L, Gehlsen K, Wayner E, Carter W, Engvall E, Ruoslahti E. Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor. J Cell Biol. 1989;109:2455-62 pubmed

product information

Internal ID :

7738

Name :

P4H9

Depositor Name :

Wayner, E.A. / Carter, W.G.

Depositor Institution :

Fred Hutchison Cancer Research Center,

Date Deposited :

10/11/11

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

CD18 (integrin beta-2; beta subunit of CD11a, b, c), human

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG3

Isotype for catalog (legacy) :

IgG3

Positive Tested Species Reactivity :

Human

Species Tested (legacy) :

human

Initial Publication Pubmed ID :

2530239

Depositor Notes (Special Instructions) :

Inhibits leukocyte binding to ICAM. Immunostaining: methanol fixation. Binds hematopoietic cells.

Collections :

CD antigens,Cell adhesion,Cell markers,Cell signaling,Human

Search Keywords :

Wayner, E.A. / Carter, W.G., CD18 (integrin beta-2; beta subunit of CD11a, b, c), human, Human, MIgG3, Human, ITGB2, CD18, MFI7, LAD, LCAMB, LFA-1, MAC-1, AB_2619602, monoclonal, Human/Cell signaling/Cluster Determinant antigens/Cell adhesion/Cell markers, Immunohistochemistry/Function Blocking/FACS

Antigen Molecular Weight :

Predicted: 85 kDa; Apparent: 93 kDa

Gene :

ITGB2

Alternate Gene Name(s) :

CD18, MFI7, LAD, LCAMB, LFA-1, MAC-1

Uniprot ID :

P05107

Antibody Registry ID :

AB_2619602

Synonyms (Alternate Clone Names) :

60.3

Immunogen :

human lymphokine activated T-cells (LAK)

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Myeloma Strain :

BALB/c MOPC2 NSI/1

Epitope Mapped :

Recommended Applications :

FACS,Function Blocking,Immunohistochemistry

Immunoblotting (legacy) :

Function Blocking Pubmed IDs :

7683214

FACS Pubmed IDs :

2530239 7683214

Additional Information :

CD18 is a general marker of leukocytes.

DSHB Growth Medium :

RPMI

References (legacy) :

J. Cell Biol. 109, 2455-2462.; Blood 81(9), 2272-2282.; J. Immunol. 173, 4179-1489.; Methods in Enzymology 42, 117-153.

more info or order :

Developmental Studies Hybridoma Bank product webpage