Disabled protein | Developmental Studies Hybridoma Bank P4D11 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Disabled protein

catalog :

P4D11

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P4D11

reactivity :

fruit fly

application :

ELISA, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 4

Reference
Kannan R, Cox E, Wang L, Kuzina I, Gu Q, Giniger E. Tyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance. Development. 2018;145: pubmed publisher
Kannan R, Song J, Karpova T, Clarke A, Shivalkar M, Wang B, et al. The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila. Development. 2017;144:487-498 pubmed publisher
Song J, Kannan R, Merdes G, Singh J, Mlodzik M, Giniger E. Disabled is a bona fide component of the Abl signaling network. Development. 2010;137:3719-27 pubmed publisher
Le Gall M, De Mattei C, Giniger E. Molecular separation of two signaling pathways for the receptor, Notch. Dev Biol. 2008;313:556-67 pubmed

product information

Internal ID :

3267

Name :

P4D11

Depositor Name :

Giniger, E.

Depositor Institution :

NIH (NINDS)

Date Deposited :

3/12/04

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Disabled protein

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

18062953

Depositor Notes (Special Instructions) :

P4D11 is recommended for Immunoprecipitation, and P6E11 is recommended for Immunohistochemistry and Immunoblotting.

Collections :

Cell signaling,Drosophila antigens

Search Keywords :

Giniger, E., Disabled protein, Drosophila, MIgG1, Drosophila, Dab, CG9695, AB_528200, monoclonal, Cell signaling/Drosophila antigens, Immunoprecipitation/ELISA

Antigen Molecular Weight :

Predicted: 227 and 243 kDa (at least two isoforms); Apparent: around 280 kDa

Gene :

DAB

Alternate Gene Name(s) :

CG9695

Uniprot ID :

P98081

Antibody Registry ID :

AB_528200

Immunogen :

Recombinant Drosophila Disabled protein (N-terminal 2/3)/His(6)-tagged protein

Immunogen Sequence :

Partial protein

Clonality :

Monoclonal

Epitope Mapped :

Yes

Epitope Location or Sequence :

N-terminal 2/3 of the protein

Epitope Map PubMed ID :

18062953

Recommended Applications :

ELISA,Immunoprecipitation

Immunoprecipitation Pubmed IDs :

18062953 20940230

ELISA Pubmed IDs :

18062953

Additional Information :

P4D11 gives some nonspecific background by Immunohistochemistry (P6E11 gives less background) [PMID 18062953].

DSHB Growth Medium :

RPMI

References (legacy) :

Dev. Biol. 313, 556-567.

more info or order :

Developmental Studies Hybridoma Bank product webpage