product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Endoglin/CD105/TGF-receptor III complex
catalog :
P4A4
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
P4A4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 3
Reference
Muenzner P, Kengmo Tchoupa A, Klauser B, Brunner T, Putze J, Dobrindt U, et al. Uropathogenic E. coli Exploit CEA to Promote Colonization of the Urogenital Tract Mucosa. PLoS Pathog. 2016;12:e1005608 pubmed publisher
Schrobback K, Wrobel J, Hutmacher D, Woodfield T, Klein T. Stage-specific embryonic antigen-4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells. Tissue Eng Part A. 2013;19:1316-26 pubmed publisher
Muenzner P, Rohde M, Kneitz S, Hauck C. CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol. 2005;170:825-36 pubmed
product information
Internal ID :
1046
Name :
P4A4
Depositor Name :
Wayner, E.A. / Vercellotti, G.
Depositor Institution :
University of Minnesota
Depositor Website :
https://www.dom.umn.edu/bio/dom-a-z/gregory-vercellotti
Date Deposited :
2/12/97
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Endoglin/CD105/TGF-receptor III complex
Antigen Species :
Human
Host Species :
mouse
Isotype :
MIgG2b, kappa light chain
Isotype for catalog (legacy) :
IgG2b, kappa light chain
Positive Tested Species Reactivity :
Human,Monkey,Mouse,Porcine,Rat
Species Tested (legacy) :
human
Initial Publication Pubmed ID :
9331949
Depositor Notes (Special Instructions) :
P4A4 may also be used to activate T cell binding to endothelium.
Collections :
CD antigens,Cell adhesion,Cell markers,Cell signaling,Cytoskeleton,Human
Search Keywords :
Wayner, E.A. / Vercellotti, G. , Endoglin/CD105/TGF-receptor III complex, Human, MIgG2b, kappa light chain, Human Mouse Rat Monkey Porcine, ENG , CD105, END, HHT1, ORW, ORW1, AB_528222, Monoclonal , Human Cell markers CD antigens Cell adhesion Cell signaling, Western blot Immunofluorescence Immunoprecipitation Function blocking Immunohistochemistry
Antigen Molecular Weight :
90 kDa (monomer) and 180 kDa (dimer)
Gene :
ENG
Alternate Gene Name(s) :
CD105, END, HHT1, ORW, ORW1
Uniprot ID :
P17813
Antibody Registry ID :
AB_528222
Synonyms (Alternate Clone Names) :
CD105
Immunogen :
Human unbilical vein endothelial cells
Immunogen Sequence :
Full length sequence
Clonality :
Monoclonal
Myeloma Strain :
NS-I/FOX-NY
Epitope Mapped :
Yes
Epitope Location or Sequence :
a.a. 277-331
Epitope Map PubMed ID :
9331949
Recommended Applications :
Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
11573204
Immunofluorescence Pubmed IDs :
15084601 27171273
Western Blot Pubmed IDs :
15084601 22192717 9331949 17058229 22192717 16115956
Immunoprecipitation Pubmed IDs :
16785228
Function Blocking Pubmed IDs :
16115956
FACS Pubmed IDs :
21310938 23301556 24777481 27171273 11573204 22552254 17058229 21638206 16115956 26818701 23301556 29080903
Additional Information :
RRID: AB_528222
DSHB Growth Medium :
RPMI
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US