product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
PECAM1 (CD31)
catalog :
P2B1
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
P2B1
reactivity :
human, mouse, rat, dog
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 15
Reference
Nagaraju S, Truong D, Mouneimne G, Nikkhah M. Microfluidic Tumor-Vascular Model to Study Breast Cancer Cell Invasion and Intravasation. Adv Healthc Mater. 2018;7:e1701257 pubmed publisher
Vranka J, Bradley J, Yang Y, Keller K, Acott T. Mapping molecular differences and extracellular matrix gene expression in segmental outflow pathways of the human ocular trabecular meshwork. PLoS ONE. 2015;10:e0122483 pubmed publisher
Dan M, Cochran D, Yokel R, Dziubla T. Binding, transcytosis and biodistribution of anti-PECAM-1 iron oxide nanoparticles for brain-targeted delivery. PLoS ONE. 2013;8:e81051 pubmed publisher
Cochran D, Wattamwar P, Wydra R, Hilt J, Anderson K, Eitel R, et al. Suppressing iron oxide nanoparticle toxicity by vascular targeted antioxidant polymer nanoparticles. Biomaterials. 2013;34:9615-22 pubmed publisher
Cassano M, Berardi E, Crippa S, Toelen J, Barthelemy I, Micheletti R, et al. Alteration of cardiac progenitor cell potency in GRMD dogs. Cell Transplant. 2012;21:1945-67 pubmed publisher
Sorrell J, Baber M, Traktuev D, March K, Caplan A. The creation of an in vitro adipose tissue that contains a vascular-adipocyte complex. Biomaterials. 2011;32:9667-76 pubmed publisher
Valentini X, Gossiaux A, Caron N, Nonclercq D, Legrand A, Toubeau G. Monoclonal antibody to CD31 (PECAM-1) inhibits tubular regeneration after ischemia reperfusion injury in the rat. Nephron Exp Nephrol. 2011;118:e60-8 pubmed publisher
Ma W, Zhao L, Fontainhas A, Fariss R, Wong W. Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD. PLoS ONE. 2009;4:e7945 pubmed publisher
Young H, Duplaa C, Yost M, Henson N, Floyd J, Detmer K, et al. Clonogenic analysis reveals reserve stem cells in postnatal mammals. II. Pluripotent epiblastic-like stem cells. Anat Rec A Discov Mol Cell Evol Biol. 2004;277:178-203 pubmed
Young H, Black A. Adult stem cells. Anat Rec A Discov Mol Cell Evol Biol. 2004;276:75-102 pubmed
Young H. Existence of reserve quiescent stem cells in adults, from amphibians to humans. Curr Top Microbiol Immunol. 2004;280:71-109 pubmed
Nielsen P, Beahm D, Giepmans B, Baruch A, Hall J, Kumar N. Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1. J Biol Chem. 2002;277:38272-83 pubmed
Voura E, Chen N, Siu C. Platelet-endothelial cell adhesion molecule-1 (CD31) redistributes from the endothelial junction and is not required for the transendothelial migration of melanoma cells. Clin Exp Metastasis. 2000;18:527-32 pubmed
Young H, Steele T, Bray R, Hudson J, Floyd J, Hawkins K, et al. Human reserve pluripotent mesenchymal stem cells are present in the connective tissues of skeletal muscle and dermis derived from fetal, adult, and geriatric donors. Anat Rec. 2001;264:51-62 pubmed
Brooks P, Stromblad S, Klemke R, Visscher D, Sarkar F, Cheresh D. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest. 1995;96:1815-22 pubmed
product information
Internal ID :
1081
Name :
P2B1
Depositor Name :
Wayner, E.A. / Vercellotti, G.
Depositor Institution :
Fred Hutchinson Cancer Research Center
Date Deposited :
8/4/93
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
PECAM1 (CD31)
Antigen Species :
Human
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Canine,Human,Mouse,Rat
Species Tested (legacy) :
human
Initial Publication Pubmed ID :
7560073
Depositor Notes (Special Instructions) :
This antibody doesn't appear to work for western blotting.
Collections :
CD antigens,Cell adhesion,Human,Skeletal muscle
Search Keywords :
Wayner, E.A. / Vercellotti, G., PECAM1 (CD31), Human, MIgG1, Human/Mouse/Canine, PECAM1, CD31, EndoCAM, GPIIA', PECA1, AB_528430, monoclonal, Cell adhesion/Human/Skeletal muscle/Cluster Determinant antigens, Immunohistochemistry/Immunofluorescence/Immunoprecipitation
Antigen Molecular Weight :
Multiple isoforms; Predicted: 76 to 80 kDa; Apparent: 120 kDa
Gene :
PECAM1
Alternate Gene Name(s) :
CD31, EndoCAM, GPIIA', PECA1
Uniprot ID :
P16284
Antibody Registry ID :
AB_528430
Synonyms (Alternate Clone Names) :
CD31
Immunogen :
IL-1beta activated human umbilical vein endothelial cells.
Immunogen Sequence :
Full length protein
Clonality :
Monoclonal
Myeloma Strain :
Fox NY
Epitope Mapped :
Yes
Epitope Location or Sequence :
extracellular
Epitope Map PubMed ID :
24016851
Recommended Applications :
Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation
Immunoblotting (legacy) :
No
Immunohistochemistry Pubmed IDs :
11505371 14699636 14983513 14594208
Immunofluorescence Pubmed IDs :
7560073 25826404 22513051 21959010 11592310 12154091 24016851 29334196 29334196
Function Blocking Pubmed IDs :
21228600
DSHB Growth Medium :
RPMI
References (legacy) :
Anat. Rec. 264, 51-62.; Curr. Top. Microbiol. Immunol. 280, 71-109.; Anat. Rec. Part A 276A, 75-102.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US