Math1 (Atoh1) | Developmental Studies Hybridoma Bank Math1 (Atoh1) product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Math1 (Atoh1)

catalog :

Math1 (Atoh1)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Math1 (Atoh1)

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 12

Reference
Zhou Y, Hu Z. Epigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like Cells. Front Cell Neurosci. 2016;10:185 pubmed publisher
Duval N, Daubas P, Bourcier de Carbon C, St Cloment C, Tinevez J, Lopes M, et al. Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord. Development. 2014;141:1726-36 pubmed publisher
Ma S, Kwon H, Huang Z. Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation. J Neurosci. 2012;32:14979-93 pubmed publisher
Miyata T, Ono Y, Okamoto M, Masaoka M, Sakakibara A, Kawaguchi A, et al. Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. 2010;5:23 pubmed publisher
Ayrault O, Zindy F, Rehg J, Sherr C, Roussel M. Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma. Mol Cancer Res. 2009;7:33-40 pubmed publisher
Brännvall K, Corell M, Forsberg Nilsson K, Fex Svenningsen A. Environmental cues from CNS, PNS, and ENS cells regulate CNS progenitor differentiation. Neuroreport. 2008;19:1283-9 pubmed publisher
Scheffer D, Sage C, Corey D, Pingault V. Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells. FEBS Lett. 2007;581:4651-6 pubmed
Allen B, Tenzen T, McMahon A. The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development. Genes Dev. 2007;21:1244-57 pubmed
Chizhikov V, Lindgren A, Currle D, Rose M, Monuki E, Millen K. The roof plate regulates cerebellar cell-type specification and proliferation. Development. 2006;133:2793-804 pubmed
Shimizu T, Tsujigiwa H, Nagatsuka H, Okafuji N, Kurihara S, Nagai N, et al. Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice. Angle Orthod. 2005;75:993-5 pubmed
Su H, Muguruma K, Matsuo Takasaki M, Kengaku M, Watanabe K, Sasai Y. Generation of cerebellar neuron precursors from embryonic stem cells. Dev Biol. 2006;290:287-96 pubmed
Saba R, Johnson J, Saito T. Commissural neuron identity is specified by a homeodomain protein, Mbh1, that is directly downstream of Math1. Development. 2005;132:2147-55 pubmed

product information

Internal ID :

2737

Name :

Math1 (Atoh1)

Depositor Name :

Johnson, J.

Depositor Institution :

UT Southwestern

Date Deposited :

7/25/02

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Math1 (Atoh1)

Antigen Species :

Mouse

Host Species :

mouse

Isotype :

MIgG1, kappa light chain

Isotype for catalog (legacy) :

IgG1, kappa light chain

Positive Tested Species Reactivity :

Mouse

Species Tested (legacy) :

mouse

Initial Publication Pubmed ID :

16448243

Depositor Notes (Special Instructions) :

Doesn't work on Chicken. Expression in neuronal progenitor cells in dorsal neural tube, EGL of cerebellum, hair cells in inner ear, Merkel cells in skin. Doesn't appear to have a functional effect.

Collections :

Cell signaling,Neurodevelopment,Transcription factors

Search Keywords :

Johnson, J., Math1 (Atoh1), Mouse, MIgG1, kappa light chain, Mouse, Atoh1, Ath1, AB_10805299, monoclonal, Cell signaling/Neurodevelopment/Transcription factors, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation

Antigen Molecular Weight :

Predicted: 38 kDa

Gene :

Atoh1

Alternate Gene Name(s) :

Ath1

Uniprot ID :

P48985

Antibody Registry ID :

AB_10805299

Synonyms (Alternate Clone Names) :

Atoh1

Immunogen :

Rcombinant Math1/GST fusion protein

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

yes

Immunohistochemistry Pubmed IDs :

16448243 29848488

Immunofluorescence Pubmed IDs :

16790481 16406324 23100420 27536218 24715462 18695508 20809939

Western Blot Pubmed IDs :

19147535

FFPE Pubmed IDs :

29848488

Pubmed IDs :

17504941

DSHB Growth Medium :

Iscove's

References (legacy) :

Neuron, 31, 219-232.; Angle Orthod. 75(6), 993-995.; Development 132, 2147-2155.; FEBS Lett 581, 4651-4656.

more info or order :

Developmental Studies Hybridoma Bank product webpage