Glucagon-like peptide 1 receptor | Developmental Studies Hybridoma Bank Mab 3F52 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Glucagon-like peptide 1 receptor

catalog :

Mab 3F52

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Mab 3F52

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 3

Reference
Jones B, Buenaventura T, Kanda N, Chabosseau P, Owen B, Scott R, et al. Targeting GLP-1 receptor trafficking to improve agonist efficacy. Nat Commun. 2018;9:1602 pubmed publisher
Waser B, Blank A, Karamitopoulou E, Perren A, Reubi J. Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Mod Pathol. 2015;28:391-402 pubmed publisher
Pyke C, Heller R, Kirk R, Ørskov C, Reedtz Runge S, Kaastrup P, et al. GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody. Endocrinology. 2014;155:1280-90 pubmed publisher

product information

Internal ID :

20387

Name :

Mab 3F52

Depositor Name :

Knudsen, L.B.

Depositor Institution :

Novo Nordisk A/S

Date Deposited :

2/25/16

Allow Hybridoma Distribution :

Cells Available (legacy) :

Antigen :

Glucagon-like peptide 1 receptor

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Positive Tested Species Reactivity :

Human,Primate

Initial Publication Pubmed ID :

24467746

Depositor Notes (Special Instructions) :

GLP1R knockout mice on a C57BL background were used for immunization. The antibody is predicted to be nonreactive in species lacking Trp33. These species include mouse, rat, goat, rabbit, pig, cow, cat and dog.

Collections :

Cell markers,Cell signaling,Human

Search Keywords :

Knudsen, L.B., Glucagon-like peptide 1 receptor, Human, , Human/Primate, GLP1R, , , Monoclonal, Human/Cell Markers/Cell Signaling, Immunohistochemistry/Immunofluorescence/Western blot/FFPE/Function Blocking/ELISA

Antigen Molecular Weight :

53.0 kDa

Gene :

GLP1R

Uniprot ID :

P43220

Antibody Registry ID :

AB_2618100

Immunogen :

GLP-1R extracellular domain (refolded)

Immunogen Sequence :

aa 24-145

Clonality :

Monoclonal

Myeloma Strain :

P3X63Ag8.653

Epitope Mapped :

Yes

Epitope Location or Sequence :

24467746

Epitope Map PubMed ID :

24467746

Recommended Applications :

ELISA,FFPE,Function Blocking,Immunofluorescence,Immunohistochemistry,Western Blot

Immunohistochemistry Pubmed IDs :

24467746 25216224

Immunofluorescence Pubmed IDs :

24467746 31390560

Western Blot Pubmed IDs :

24467746 31390560

ELISA Pubmed IDs :

24467746

FFPE Pubmed IDs :

24467746 25216224

Function Blocking Pubmed IDs :

24467746

Depositor Growth Medium :

RPMI 1640+10%FCS

Additional Information :

Purification of the E. coli recombinant extracellular domain of GLP-1 has been described (PUBMED 17444618).

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage