mineralocorticoid receptor | Developmental Studies Hybridoma Bank MRN2 2B7 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

mineralocorticoid receptor

catalog :

MRN2 2B7

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MRN2 2B7

reactivity :

rat

application :

western blot, immunohistochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 4

Reference
Gomez Sanchez C, Warden M, Gomez Sanchez M, Hou X, Gomez Sanchez E. Diverse immunostaining patterns of mineralocorticoid receptor monoclonal antibodies. Steroids. 2011;76:1541-5 pubmed publisher
Gomez Sanchez E, Gomez Sanchez M, de Rodriguez A, Romero D, Warden M, Plonczynski M, et al. Immunohistochemical demonstration of the mineralocorticoid receptor, 11beta-hydroxysteroid dehydrogenase-1 and -2, and hexose-6-phosphate dehydrogenase in rat ovary. J Histochem Cytochem. 2009;57:633-41 pubmed publisher
Rigsby C, Burch A, Ogbi S, Pollock D, Dorrance A. Intact female stroke-prone hypertensive rats lack responsiveness to mineralocorticoid receptor antagonists. Am J Physiol Regul Integr Comp Physiol. 2007;293:R1754-63 pubmed
Gomez Sanchez C, de Rodriguez A, Romero D, Estess J, Warden M, Gomez Sanchez M, et al. Development of a panel of monoclonal antibodies against the mineralocorticoid receptor. Endocrinology. 2006;147:1343-8 pubmed

product information

Internal ID :

3466

Name :

MRN2 2B7

Depositor Name :

Gomez-Sanchez, C.

Depositor Institution :

G.V. Montgomery VA Medical Center

Date Deposited :

10/2/07

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

mineralocorticoid receptor

Antigen Species :

Rat

Host Species :

mouse

Isotype :

MIgG2b, kappa light chain

Isotype for catalog (legacy) :

IgG2b, kappa light chain

Positive Tested Species Reactivity :

Rat

Species Tested (legacy) :

rat

Initial Publication Pubmed ID :

16293659

Collections :

Cell signaling,Nucleus,Transcription factors

Search Keywords :

Gomez-Sanchez, C., mineralocorticoid receptor, Rat, MIgG2b, kappa light chain, Rat, Nr3c2, Mlr, MCR, AB_1157907, monoclonal, Cell signaling/Transcription factors/Nucleus, Immunohistochemistry/western blot

Antigen Molecular Weight :

Predicted: 107 kDa; Apparent: 107 kDa

Gene :

Nr3c2

Alternate Gene Name(s) :

Mlr, MCR

Uniprot ID :

P22199

Antibody Registry ID :

AB_1157907

Synonyms (Alternate Clone Names) :

rMR 64-82 2B7

Immunogen :

SKEKHELLPYIQQDNSRSG+C (KLH)

Immunogen Sequence :

Partial protein

Clonality :

Monoclonal

Myeloma Strain :

SP2

Epitope Mapped :

Yes

Epitope Location or Sequence :

N-terminus A/B domain (aa 64-82)

Epitope Map PubMed ID :

16293659

Recommended Applications :

Immunohistochemistry,Western Blot

Immunoblotting (legacy) :

Yes

Immunohistochemistry Pubmed IDs :

16293659 19255253

Western Blot Pubmed IDs :

16293659 17670862 19255253 21945398

Additional Information :

Should recognize all MR isoforms. The sequence of the rMR 64–82 peptide differs between the rat and, human or mouse.

DSHB Growth Medium :

Iscove's

References (legacy) :

Endocrinology 147:1343-1348.

more info or order :

Developmental Studies Hybridoma Bank product webpage