product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
endoglin (CD105)
catalog :
MJ7/18
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MJ7/18
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
more info or order :
citations: 23
Published Application/Species/Sample/Dilution | Reference |
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Kinderlerer A, Pombo Gregoire I, Hamdulay S, Ali F, Steinberg R, Silva G, et al. Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin. Blood. 2009;113:1598-607 pubmed publisher
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Mason J, Lidington E, Yarwood H. Isolation and analysis of large and small vessel endothelial cells. Methods Mol Med. 2007;135:305-21 pubmed
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Korpanty G, Carbon J, Grayburn P, Fleming J, Brekken R. Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature. Clin Cancer Res. 2007;13:323-30 pubmed
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Korpanty G, Grayburn P, Shohet R, Brekken R. Targeting vascular endothelium with avidin microbubbles. Ultrasound Med Biol. 2005;31:1279-83 pubmed
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Redaelli C, Semela D, Carrick F, Ledermann M, Candinas D, Sauter B, et al. Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice. J Hepatol. 2004;40:305-12 pubmed
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Ahmad S, Lidington E, Ohta R, Okada N, Robson M, Davies K, et al. Decay-accelerating factor induction by tumour necrosis factor-alpha, through a phosphatidylinositol-3 kinase and protein kinase C-dependent pathway, protects murine vascular endothelial cells against complement deposition. Immunology. 2003;110:258-68 pubmed
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Garton K, Gough P, Philalay J, Wille P, Blobel C, Whitehead R, et al. Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17). J Biol Chem. 2003;278:37459-64 pubmed
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Charbord P, Oostendorp R, Pang W, Herault O, Noel F, Tsuji T, et al. Comparative study of stromal cell lines derived from embryonic, fetal, and postnatal mouse blood-forming tissues. Exp Hematol. 2002;30:1202-10 pubmed
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Lidington E, Rao R, Marelli Berg F, Jat P, Haskard D, Mason J. Conditional immortalization of growth factor-responsive cardiac endothelial cells from H-2K(b)-tsA58 mice. Am J Physiol Cell Physiol. 2002;282:C67-74 pubmed
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Izawa D, Tanaka T, Saito K, Ogihara H, Usui T, Kawamoto S, et al. Expression profile of active genes in mouse lymph node high endothelial cells. Int Immunol. 1999;11:1989-98 pubmed
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Kruse A, Hallmann R, Butcher E. Specialized patterns of vascular differentiation antigens in the pregnant mouse uterus and the placenta. Biol Reprod. 1999;61:1393-401 pubmed
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Ge A, Butcher E. Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-beta ligand. Gene. 1994;138:201-6 pubmed
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Hallmann R, Mayer D, Berg E, Broermann R, Butcher E. Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier. Dev Dyn. 1995;202:325-32 pubmed
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Engelhardt B, Conley F, Butcher E. Cell adhesion molecules on vessels during inflammation in the mouse central nervous system. J Neuroimmunol. 1994;51:199-208 pubmed
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product information
Internal ID :
1642
Name :
MJ7/18
Depositor Name :
Butcher, E.C. / Jutila, M.
Depositor Institution :
Stanford University School of Medicine and Montana State University
Date Deposited :
8/4/95
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
endoglin (CD105)
Antigen Species :
Rat
Host Species :
rat
Isotype :
RIgG2a
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
Mouse
Species Tested (legacy) :
mouse; other species not tested
Initial Publication Pubmed ID :
8125301
Depositor Notes (Special Instructions) :
Pan endothelial marker with an extremely weak (minimal) reactivity with early hematopoetic cells (J. Spangrude, personal communication).
Collections :
CD antigens
Search Keywords :
Butcher, E.C. / Jutila, M., endoglin (CD105), Rat, RIgG2a, Mouse, Eng, CD105, Edg, Endo, AB_2262267, monoclonal, Cluster Determinant antigens, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation/FACS
Antigen Molecular Weight :
Predicted: 70 kDa; Apparent: 180 kDa (nonreduced) or 90 (reduced)
Gene :
Eng
Alternate Gene Name(s) :
CD105, Edg, Endo
Uniprot ID :
Q63961
Antibody Registry ID :
AB_2262267
Synonyms (Alternate Clone Names) :
CD105
Immunogen :
Inflamed mouse skin
Immunogen Sequence :
Full length protein
Clonality :
Monoclonal
Myeloma Strain :
SP2/0
Epitope Mapped :
Yes
Epitope Location or Sequence :
extracellular domain
Epitope Map PubMed ID :
8125301
Recommended Applications :
FACS,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunohistochemistry Pubmed IDs :
7626790 7514186 21444673 14739103
Immunofluorescence Pubmed IDs :
10569981 16176794 17200371 21708981 21444673 19356684 12384152
Western Blot Pubmed IDs :
8125301 21708981 12384152
Immunoprecipitation Pubmed IDs :
21708981
FACS Pubmed IDs :
8125301 16176794 11742799 10590265 19036700 12384152
Pubmed IDs :
27179250 25883219 19811096 24547782 12878595 14511240 17951667
Additional Information :
Endoglin is a major glycoprotein of vascular endothelium. MJ7/18 is commonly used for the isolation of murine endothelial cells.
DSHB Growth Medium :
RPMI
References (legacy) :
Gene 138, 201-206.
more info or order :
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Developmental Studies Hybridoma Bank
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