SMN1 protein, exon 2 | Developmental Studies Hybridoma Bank MANSMA14(6A6) product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

SMN1 protein, exon 2

catalog :

MANSMA14(6A6)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MANSMA14(6A6)

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 1

Reference
Young P, Man N, Lorson C, Le T, Androphy E, Burghes A, et al. The exon 2b region of the spinal muscular atrophy protein, SMN, is involved in self-association and SIP1 binding. Hum Mol Genet. 2000;9:2869-77 pubmed

product information

Internal ID :

7400

Name :

MANSMA14(6A6)

Depositor Name :

Morris, G.E.

Depositor Institution :

Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK

Date Deposited :

6/29/11

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

SMN1 protein, exon 2

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Human,Mouse

Species Tested (legacy) :

human, mouse

Initial Publication Pubmed ID :

11092763

Depositor Notes (Special Instructions) :

Stains only SMN band in HeLa total protein extract. Stains dot-like structures (gems) in the nucleus.

Collections :

Human,Muscular dystrophy,Skeletal muscle

Search Keywords :

Morris, G.E., SMN1 protein, exon 2, Human, MIgG1, Human/Mouse, SMN1, SMN, SMNT, SMN2, SMNC, Gemin1, AB_2618232, monoclonal, Human/Muscular dystrophy/Skeletal muscle, Immunofluorescence/Western Blot/ELISA

Antigen Molecular Weight :

Predicted: 32 kDa; Apparent: 38 kDa

Gene :

SMN1

Alternate Gene Name(s) :

SMN, SMNT, SMN2, SMNC, Gemin1

Uniprot ID :

Q16637

Antibody Registry ID :

AB_2618232

Synonyms (Alternate Clone Names) :

MANSMA14

Immunogen :

Recombinant SMN protein

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Myeloma Strain :

Sp2/0

Epitope Mapped :

Yes

Epitope Location or Sequence :

exon 2, aa 28-91 (conformational epitope)

Epitope Map PubMed ID :

11092763

Recommended Applications :

ELISA,Immunofluorescence,Western Blot

Immunoblotting (legacy) :

yes

Immunofluorescence Pubmed IDs :

11092763

Western Blot Pubmed IDs :

11092763

ELISA Pubmed IDs :

11092763

Additional Characterization :

http://www.glennmorris.org.uk/datasheets/MANSMA14(6A6).doc

DSHB Growth Medium :

Iscove's

References (legacy) :

Exp. Cell Res. 256, 365-374.

more info or order :

Developmental Studies Hybridoma Bank product webpage