dystrophin | Developmental Studies Hybridoma Bank MANDYS102(7D2) product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

dystrophin

catalog :

MANDYS102(7D2)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MANDYS102(7D2)

reactivity :

human, chicken

application :

western blot, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; chicken; 1:5	Wahlin K, Moreira E, Huang H, Yu N, Adler R. Molecular dynamics of photoreceptor synapse formation in the developing chick retina. J Comp Neurol. 2008;506:822-37 pubmed
	Hori S, Ohtani S, Nguyen T, Morris G. The N-terminal half of dystrophin is protected from proteolysis in situ. Biochem Biophys Res Commun. 1995;209:1062-7 pubmed
	Nguyen T, Morris G. Use of epitope libraries to identify exon-specific monoclonal antibodies for characterization of altered dystrophins in muscular dystrophy. Am J Hum Genet. 1993;52:1057-66 pubmed
	Helliwell T, Ellis J, Mountford R, Appleton R, Morris G. A truncated dystrophin lacking the C-terminal domains is localized at the muscle membrane. Am J Hum Genet. 1992;50:508-14 pubmed
	Nguyen T, Ginjaar I, van Ommen G, Morris G. Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections. Biochem J. 1992;288 ( Pt 2):663-8 pubmed

product information

Internal ID :

3742

Name :

MANDYS102(7D2)

Depositor Name :

Morris, G.E.

Depositor Institution :

Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK

Date Deposited :

7/13/06

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

dystrophin

Antigen Species :

human

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG2a

Positive Tested Species Reactivity :

Human

Species Tested (legacy) :

human (not mouse, not Xenopus, not chick)

Initial Publication Pubmed ID :

7684887

Depositor Notes (Special Instructions) :

This antibody does not work with mouse, xenopus, or chicken. Has weak crosscreativity in Immunofluorescence with utrophin.

Search Keywords :

Morris, dystrophin, dmd, monoclonal, IgG1, human, Immunofluorescence,Western Blot

Gene :

DMD

Uniprot ID :

P11532

Antibody Registry ID :

AB_2618155

Clonality :

Monoclonal

Epitope Mapped :

Yes

Epitope Location or Sequence :

ex43, 2047-2105

Recommended Applications :

Immunofluorescence,Western Blot

Immunoblotting (legacy) :

Yes

Pubmed IDs :

1281410 1539591 7733959

Additional Information :

RRID:AB_2618155

Additional Characterization :

http://www.glennmorris.org.uk/datasheets/MANDYS102(7D2).doc

DSHB Growth Medium :

Iscove's

References (legacy) :

Biochem. J. 288, 663-668.; Am. J. Hum. Genet. 52, 1057-1066.

more info or order :

Developmental Studies Hybridoma Bank product webpage