product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
utrophin
catalog :
MANCHO14(4E1)
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MANCHO14(4E1)
reactivity :
human, mouse
application :
western blot, immunocytochemistry
more info or order :
citations: 2
| Reference |
|---|
Morris G, Sedgwick S, Ellis J, Pereboev A, Chamberlain J, Nguyen thi Man -. An epitope structure for the C-terminal domain of dystrophin and utrophin. Biochemistry. 1998;37:11117-27 pubmed
|
Nguyen T, Ellis J, Love D, Davies K, Gatter K, Dickson G, et al. Localization of the DMDL gene-encoded dystrophin-related protein using a panel of nineteen monoclonal antibodies: presence at neuromuscular junctions, in the sarcolemma of dystrophic skeletal muscle, in vascular and other smooth muscles, and in proli. J Cell Biol. 1991;115:1695-700 pubmed
|
product information
Internal ID :
7817
Name :
MANCHO14(4E1)
Depositor Name :
Morris, G.E.
Depositor Institution :
Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, UK
Date Deposited :
11/24/11
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
utrophin
Antigen Species :
human
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila,Fish,Human,Mouse
Species Tested (legacy) :
human, mouse, fish, Drosophila (not Xenopus)
Initial Publication Pubmed ID :
1757469
Depositor Notes (Special Instructions) :
This antibody has crossreactivity with dystrophin. Doesn't work on Xenopus.
Collections :
Drosophila antigens,Human
Search Keywords :
morris, utrophin, dmd, monoclonal, human, IgG1, Immunofluorescence,Western Blot
Gene :
UTRN/DMD
Uniprot ID :
P46939 P11532
Antibody Registry ID :
AB_2618133
Immunogen :
fusion protein from bacteria: the last 329 amino-acids of utrophin linked to ?-galactosidase
Clonality :
Monoclonal
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 3164-3184 in utrophin; (ex72/73, 3436-3450 in dystrophin)
Recommended Applications :
Immunofluorescence,Western Blot
Immunoblotting (legacy) :
yes
Pubmed IDs :
9693008
Additional Information :
RRID:AB_2618133
Additional Characterization :
http://www.glennmorris.org.uk/datasheets/MANCHO14(4E1).doc
DSHB Growth Medium :
Iscove's
References (legacy) :
Biochem. 37, 11117-11127.
more info or order :
company information
Developmental Studies Hybridoma Bank
review
product type
related products
browse more products
questions and comments