Sex-lethal protein, female-specific isoform | Developmental Studies Hybridoma Bank M18 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Sex-lethal protein, female-specific isoform

catalog :

M18

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M18

reactivity :

fruit fly

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 24

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; fruit fly; 1:50	Hudry B, Khadayate S, Miguel Aliaga I. The sexual identity of adult intestinal stem cells controls organ size and plasticity. Nature. 2016;530:344-8 pubmed publisher
immunohistochemistry; fruit fly	Hashiyama K, Hayashi Y, Kobayashi S. Drosophila Sex lethal gene initiates female development in germline progenitors. Science. 2011;333:885-8 pubmed publisher
	Kan L, Grozhik A, Vedanayagam J, Patil D, Pang N, Lim K, et al. The m6A pathway facilitates sex determination in Drosophila. Nat Commun. 2017;8:15737 pubmed publisher
	Hessinger C, Technau G, Rogulja Ortmann A. The Drosophila Hox gene Ultrabithorax acts in both muscles and motoneurons to orchestrate formation of specific neuromuscular connections. Development. 2017;144:139-150 pubmed publisher
	Clemente Ruiz M, Murillo Maldonado J, Benhra N, Barrio L, PÃ©rez L, Quiroga G, et al. Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis. Dev Cell. 2016;36:290-302 pubmed publisher
	Vogler G, Liu J, Iafe T, Migh E, Mihaly J, Bodmer R. Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis. J Cell Biol. 2014;206:909-22 pubmed publisher
	Yan D, Neumüller R, BUCKNER M, Ayers K, Li H, Hu Y, et al. A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell. 2014;28:459-73 pubmed publisher
	Harumoto T, Anbutsu H, Fukatsu T. Male-killing Spiroplasma induces sex-specific cell death via host apoptotic pathway. PLoS Pathog. 2014;10:e1003956 pubmed publisher
	Joyce E, Apostolopoulos N, Beliveau B, Wu C. Germline progenitors escape the widespread phenomenon of homolog pairing during Drosophila development. PLoS Genet. 2013;9:e1004013 pubmed publisher
	Sinden D, Badgett M, Fry J, Jones T, Palmen R, Sheng X, et al. Jak-STAT regulation of cyst stem cell development in the Drosophila testis. Dev Biol. 2012;372:5-16 pubmed publisher
	Chau J, Kulnane L, Salz H. Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis. Proc Natl Acad Sci U S A. 2012;109:9465-70 pubmed publisher
	Kolahgar G, Bardet P, Langton P, Alexandre C, Vincent J. Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila. Development. 2011;138:3021-31 pubmed publisher
	Kitadate Y, Kobayashi S. Notch and Egfr signaling act antagonistically to regulate germ-line stem cell niche formation in Drosophila male embryonic gonads. Proc Natl Acad Sci U S A. 2010;107:14241-6 pubmed publisher
	Ogawa H, Ohta N, Moon W, Matsuzaki F. Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions. J Cell Sci. 2009;122:3242-9 pubmed publisher
	Sheng X, Posenau T, Gumulak Smith J, Matunis E, Van Doren M, Wawersik M. Jak-STAT regulation of male germline stem cell establishment during Drosophila embryogenesis. Dev Biol. 2009;334:335-44 pubmed publisher
	Sato T, Ueda S, Niki Y. Wingless signaling initiates mitosis of primordial germ cells during development in Drosophila. Mech Dev. 2008;125:498-507 pubmed publisher
	DeFalco T, Camara N, Le Bras S, Van Doren M. Nonautonomous sex determination controls sexually dimorphic development of the Drosophila gonad. Dev Cell. 2008;14:275-86 pubmed publisher
	Garbe D, O Donnell M, Bashaw G. Cytoplasmic domain requirements for Frazzled-mediated attractive axon turning at the Drosophila midline. Development. 2007;134:4325-34 pubmed
	Garbe D, Bashaw G. Independent functions of Slit-Robo repulsion and Netrin-Frazzled attraction regulate axon crossing at the midline in Drosophila. J Neurosci. 2007;27:3584-92 pubmed
	Penn J, Schedl P. The master switch gene sex-lethal promotes female development by negatively regulating the N-signaling pathway. Dev Cell. 2007;12:275-86 pubmed
	Garbe D, Das A, Dubreuil R, Bashaw G. beta-Spectrin functions independently of Ankyrin to regulate the establishment and maintenance of axon connections in the Drosophila embryonic CNS. Development. 2007;134:273-84 pubmed
	Le Bras S, Van Doren M. Development of the male germline stem cell niche in Drosophila. Dev Biol. 2006;294:92-103 pubmed
	DeFalco T, Le Bras S, Van Doren M. Abdominal-B is essential for proper sexually dimorphic development of the Drosophila gonad. Mech Dev. 2004;121:1323-33 pubmed
	Bopp D, Bell L, Cline T, Schedl P. Developmental distribution of female-specific Sex-lethal proteins in Drosophila melanogaster. Genes Dev. 1991;5:403-15 pubmed

product information

Internal ID :

2054

Name :

M18

Depositor Name :

Schedl, P.

Depositor Institution :

Princeton University

Depositor Website :

http://molbio.princeton.edu/labs/schedl/paul-schedl

Date Deposited :

3/16/99

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Sex-lethal protein, female-specific isoform

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG1, kappa light chain

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

1900493

Collections :

Cell signaling,Drosophila antigens

Search Keywords :

Schedl, P., Sex-lethal protein, female-specific isoform, Drosophila, MIgG1, kappa light chain, Drosophila, Sxl , Sx1, CG43770 , AB_528464, Monoclonal, Drosophila antigens, Immunohistochemistry/Immunofluorescence/Western blot/Immunoprecipitation

Antigen Molecular Weight :

35-38 kDa

Gene :

Sxl

Alternate Gene Name(s) :

Sx1, CG43770

Uniprot ID :

P19339

Antibody Registry ID :

AB_528464

Immunogen :

LacZ-Sxl fusion protein

Immunogen Sequence :

Full length sequence

Clonality :

Monoclonal

Myeloma Strain :

SP2/0

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunohistochemistry Pubmed IDs :

1900493

Immunofluorescence Pubmed IDs :

15454263 16566915 17121810 17276344 17392474 18003737 18267095 18291628 19690050 19643104 20660750 21693518 22645327 23010510 24385920 24550732 24576427 25267295 26859353 26887495 28675155 30562515

Western Blot Pubmed IDs :

1900493

Immunoprecipitation Pubmed IDs :

17276344

Additional Information :

RRID:AB_528464 FBgn0264270

DSHB Growth Medium :

RPMI

References (legacy) :

Genes Dev. 5, 403-415.

more info or order :

Developmental Studies Hybridoma Bank product webpage