| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2n
| Ordonez D, Lee M, Feany M. α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton. Neuron. 2018;97:108-124.e6 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 3a
- western blot; mouse; 1:2000; loading ...; fig 2a
| Krey J, Dumont R, Wilmarth P, David L, Johnson K, Barr Gillespie P. ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells. J Neurosci. 2018;38:843-857 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig 4a
| Krey J, Krystofiak E, Dumont R, Vijayakumar S, Choi D, Rivero F, et al. Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid. J Cell Biol. 2016;215:467-482 pubmed |
- western blot; mouse; fig 1
| Wang H, Wang R, Carrera I, Xu S, Lakshmana M. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. Eneuro. 2016;3: pubmed publisher |
- western blot; mouse; fig 2e
| Ro S, Xue X, Ramakrishnan S, Cho C, Namkoong S, Jang I, et al. Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis. elife. 2016;5:e12204 pubmed publisher |
- western blot; human; fig 3
| Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, et al. Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. elife. 2016;5: pubmed publisher |
- western blot; Drosophila melanogaster; 1:2000; fig 1F
| Lee S, Bang S, Hong Y, Lee J, Jeong H, Park S, et al. The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease. Dis Model Mech. 2016;9:295-306 pubmed publisher |
- western blot; Drosophila melanogaster; 1:50
| Niehues S, Bussmann J, Steffes G, Erdmann I, Köhrer C, Sun L, et al. Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nat Commun. 2015;6:7520 pubmed publisher |
- western blot; human; 1:4000; fig 1, 2
| Cuadrado E, Michailidou I, van Bodegraven E, Jansen M, Sluijs J, Geerts D, et al. Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release. J Immunol. 2015;194:3623-33 pubmed publisher |
- western blot; Drosophila melanogaster; 1:1000; fig 1
| Merlo P, Frost B, Peng S, Yang Y, Park P, Feany M. p53 prevents neurodegeneration by regulating synaptic genes. Proc Natl Acad Sci U S A. 2014;111:18055-60 pubmed publisher |
- western blot; Xenopus laevis; 1:300; fig 3
| Werner M, Mitchell J, Putzbach W, Bacon E, Kim S, Mitchell B. Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1. J Cell Biol. 2014;206:367-76 pubmed publisher |
- western blot; Drosophila melanogaster; 1:5000
| Hegde V, Vogel R, Feany M. Glia are critical for the neuropathology of complex I deficiency in Drosophila. Hum Mol Genet. 2014;23:4686-92 pubmed publisher |
- western blot; mouse; fig 5c
| Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, et al. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis. Hum Mol Genet. 2014;23:668-81 pubmed publisher |
| Pe er T, Lahmi R, Sharaby Y, Chorni E, Noach M, Vecsler M, et al. Gas2l3, a novel constriction site-associated protein whose regulation is mediated by the APC/C Cdh1 complex. PLoS ONE. 2013;8:e57532 pubmed publisher |
- western blot; Drosophila melanogaster; 1:10
| Koppen T, Weckmann A, Muller S, Staubach S, Bloch W, Dohmen R, et al. Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells. Proteomics. 2011;11:4397-410 pubmed publisher |
| Gao J, Qin A, Liu D, Ruan R, Wang Q, Yuan J, et al. Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network. Sci Adv. 2019;5:eaaw7215 pubmed publisher |
| Agabiti S, Li J, Dong W, Poe M, Wiemer A. Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition. Cell Death Dis. 2019;10:733 pubmed publisher |
| Costa T, Zhuang T, Lorent J, Turco E, Olofsson H, Masià Balagué M, et al. PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer. Nat Commun. 2019;10:3589 pubmed publisher |
| Kelly L, Almutairi M, Kursan S, Pacheco R, Dias Junior E, Castrop H, et al. Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter. Am J Physiol Cell Physiol. 2019;317:C843-C856 pubmed publisher |
| Niranjan N, Mareedu S, Tian Y, Kodippili K, Fefelova N, Voit A, et al. Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy. Am J Physiol Cell Physiol. 2019;317:C813-C824 pubmed publisher |
| Won J, Kim G, Kim J, Cho D, Kwon B, Bae Y, et al. ADAMTS Sol narae cleaves extracellular Wingless to generate a novel active form that regulates cell proliferation in Drosophila. Cell Death Dis. 2019;10:564 pubmed publisher |
| Liu X, Yao Z, Jin M, Namkoong S, Yin Z, Lee J, et al. Dhh1 promotes autophagy-related protein translation during nitrogen starvation. PLoS Biol. 2019;17:e3000219 pubmed publisher |
| Wan J, Block S, Scribano C, Thiry R, Esbona K, Audhya A, et al. Mad1 destabilizes p53 by preventing PML from sequestering MDM2. Nat Commun. 2019;10:1540 pubmed publisher |
| Denu R, Sass M, Johnson J, Potts G, Choudhary A, Coon J, et al. Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131). J Biol Chem. 2019;294:6531-6549 pubmed publisher |
| Nnah I, Wang B, Saqcena C, Weber G, Bonder E, Bagley D, et al. TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy. Autophagy. 2019;15:151-164 pubmed publisher |
| Bardai F, Ordonez D, Bailey R, Hamm M, Lewis J, Feany M. Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics. PLoS Biol. 2018;16:e2006265 pubmed publisher |
| Haque M, Mohibbullah M, Hong Y, Moon I. Calotropis gigantea Promotes Neuritogenesis and Synaptogenesis through Activation of NGF-TrkA-Erk1/2 Signaling in Rat Hippocampal Neurons. Am J Chin Med. 2018;46:1861-1877 pubmed publisher |
| Yuan L, Singh D, Buescher J, Arikkath J. A role for proteolytic regulation of δ-catenin in remodeling a subpopulation of dendritic spines in the rodent brain. J Biol Chem. 2018;293:11625-11638 pubmed publisher |
| Panikker P, Xu S, Zhang H, Sarthi J, Beaver M, Sheth A, et al. Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition. J Neurosci. 2018;38:4569-4583 pubmed publisher |
| Kell M, Riccio R, Baumgartner E, Compton Z, Pecorin P, Mitchell T, et al. Targeted deletion of the zebrafish actin-bundling protein L-plastin (lcp1). PLoS ONE. 2018;13:e0190353 pubmed publisher |
| Jantrapirom S, Lo Piccolo L, Yoshida H, Yamaguchi M. A new Drosophila model of Ubiquilin knockdown shows the effect of impaired proteostasis on locomotive and learning abilities. Exp Cell Res. 2018;362:461-471 pubmed publisher |
| Tora D, Gomez A, Michaud J, Yam P, Charron F, Scheiffele P. Cellular Functions of the Autism Risk Factor PTCHD1 in Mice. J Neurosci. 2017;37:11993-12005 pubmed publisher |
| Avery A, Thomas D, Hays T. ?-III-spectrin spinocerebellar ataxia type 5 mutation reveals a dominant cytoskeletal mechanism that underlies dendritic arborization. Proc Natl Acad Sci U S A. 2017;114:E9376-E9385 pubmed publisher |
| Kikuma K, Li X, Kim D, Sutter D, Dickman D. Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in Drosophila. Genetics. 2017;207:993-1006 pubmed publisher |
| Li Q, Kellner D, Hatch H, Yumita T, Sanchez S, Machold R, et al. Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function. PLoS Genet. 2017;13:e1006815 pubmed publisher |
| Thomas F, Goode K, Rajwa B, Bieberich A, Avramova L, Hazbun T, et al. A Chemogenomic Screening Platform Used to Identify Chemotypes Perturbing HSP90 Pathways. SLAS Discov. 2017;22:706-719 pubmed publisher |
| Rihn S, Foster T, Busnadiego I, Aziz M, Hughes J, Neil S, et al. The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block. J Virol. 2017;91: pubmed publisher |
| Celona B, Dollen J, Vatsavayai S, Kashima R, Johnson J, Tang A, et al. Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. elife. 2017;6: pubmed publisher |
| Jadhav G, Teguh D, Kenny J, Tickner J, Xu J. Morc3 mutant mice exhibit reduced cortical area and thickness, accompanied by altered haematopoietic stem cells niche and bone cell differentiation. Sci Rep. 2016;6:25964 pubmed publisher |
| Barekat A, Gonzalez A, Mauntz R, Kotzebue R, Molina B, El Mecharrafie N, et al. Using Drosophila as an integrated model to study mild repetitive traumatic brain injury. Sci Rep. 2016;6:25252 pubmed publisher |
| Williams A, White R, Siniard A, Corneveaux J, Huentelman M, Duch C. MECP2 impairs neuronal structure by regulating KIBRA. Neurobiol Dis. 2016;91:284-91 pubmed publisher |
| Shindo Y, Iwamoto K, Mouri K, Hibino K, Tomita M, Kosako H, et al. Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling. Nat Commun. 2016;7:10485 pubmed publisher |
| Cruz A, Ludovico P, Torrado E, Gama J, Sousa J, Gaifem J, et al. IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages. Front Immunol. 2015;6:498 pubmed publisher |
| Ryder D, Judge S, Beharry A, Farnsworth C, Silva J, Judge A. Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy. PLoS ONE. 2015;10:e0136247 pubmed publisher |
| Sen A, Kalvakuri S, Bodmer R, Cox R. Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila. Dis Model Mech. 2015;8:577-89 pubmed publisher |
| Loos J, Cumino A. In Vitro Anti-Echinococcal and Metabolic Effects of Metformin Involve Activation of AMP-Activated Protein Kinase in Larval Stages of Echinococcus granulosus. PLoS ONE. 2015;10:e0126009 pubmed publisher |
| Okray Z, de Esch C, Van Esch H, Devriendt K, Claeys A, Yan J, et al. A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function. EMBO Mol Med. 2015;7:423-37 pubmed publisher |
| Nandi N, Tyra L, Stenesen D, KRAMER H. Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy. J Cell Biol. 2014;207:253-68 pubmed publisher |
| Devorkin L, Go N, Hou Y, Moradian A, Morin G, Gorski S. The Drosophila effector caspase Dcp-1 regulates mitochondrial dynamics and autophagic flux via SesB. J Cell Biol. 2014;205:477-92 pubmed publisher |
| Romaker D, Kumar V, Cerqueira D, Cox R, Wessely O. MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney. Proc Natl Acad Sci U S A. 2014;111:6335-40 pubmed publisher |
| Clifford R, Kaplan J. Human breast tumor cells are more resistant to cardiac glycoside toxicity than non-tumorigenic breast cells. PLoS ONE. 2013;8:e84306 pubmed publisher |
| Gu T, Elgin S. Maternal depletion of Piwi, a component of the RNAi system, impacts heterochromatin formation in Drosophila. PLoS Genet. 2013;9:e1003780 pubmed publisher |
| Rund S, Bonar N, Champion M, Ghazi J, Houk C, Leming M, et al. Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae. Sci Rep. 2013;3:2494 pubmed publisher |
| Chow S, Tse W, Wong C. Dexamethasone (DEX) induces Osmotic stress transcription factor 1 (Ostf1) through the Akt-GSK3? pathway in freshwater Japanese eel gill cell cultures. Biol Open. 2013;2:487-91 pubmed publisher |
| Ahn B, Empinado H, Al Rajhi M, Judge A, Ferreira L. Diaphragm atrophy and contractile dysfunction in a murine model of pulmonary hypertension. PLoS ONE. 2013;8:e62702 pubmed publisher |
| Zhang F, Wang J, Xu J, Zhang Z, Koppetsch B, Schultz N, et al. UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell. 2012;151:871-884 pubmed publisher |
| Kamphuis W, Mamber C, Moeton M, Kooijman L, Sluijs J, Jansen A, et al. GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease. PLoS ONE. 2012;7:e42823 pubmed publisher |
| Hall K, Volk Draper L, Flister M, Ran S. New model of macrophage acquisition of the lymphatic endothelial phenotype. PLoS ONE. 2012;7:e31794 pubmed publisher |
| Von Stetina J, Lafever K, Rubin M, Drummond Barbosa D. A Genetic Screen for Dominant Enhancers of the Cell-Cycle Regulator ?-Endosulfine Identifies Matrimony as a Strong Functional Interactor in Drosophila. G3 (Bethesda). 2011;1:607-13 pubmed publisher |
| Etheridge T, Oczypok E, Lehmann S, Fields B, Shephard F, Jacobson L, et al. Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans. PLoS Genet. 2012;8:e1002471 pubmed publisher |
| Zhou T, Li S, Zhong W, Vihervaara T, Béaslas O, Perttilä J, et al. OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62. PLoS ONE. 2011;6:e21078 pubmed publisher |
| Milenkovic V, Krejcova S, Reichhart N, Wagner A, Strauss O. Interaction of bestrophin-1 and Ca2+ channel ?-subunits: identification of new binding domains on the bestrophin-1 C-terminus. PLoS ONE. 2011;6:e19364 pubmed publisher |
| Robbins E, Krupp A, Perez de Arce K, Ghosh A, Fogel A, Boucard A, et al. SynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning. Neuron. 2010;68:894-906 pubmed publisher |
| Li Z, Lock J, Olofsson H, Kowalewski J, Teller S, Liu Y, et al. Integrin-mediated cell attachment induces a PAK4-dependent feedback loop regulating cell adhesion through modified integrin alpha v beta 5 clustering and turnover. Mol Biol Cell. 2010;21:3317-29 pubmed publisher |
| Lim A, Tao L, Kai T. piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline. J Cell Biol. 2009;186:333-42 pubmed publisher |
| Batiz L, De Blas G, Michaut M, Ramírez A, Rodríguez F, Ratto M, et al. Sperm from hyh mice carrying a point mutation in alphaSNAP have a defect in acrosome reaction. PLoS ONE. 2009;4:e4963 pubmed publisher |
| Bossuyt W, Kazanjian A, De Geest N, Van Kelst S, De Hertogh G, Geboes K, et al. Atonal homolog 1 is a tumor suppressor gene. PLoS Biol. 2009;7:e39 pubmed publisher |
| Gan H, Lee J, Ren F, Chen M, Kornfeld H, Remold H. Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence. Nat Immunol. 2008;9:1189-97 pubmed publisher |
| Srinivasan R, Jang S, Ward R, Sachdev S, Ezashi T, Svaren J. Differential regulation of NAB corepressor genes in Schwann cells. BMC Mol Biol. 2007;8:117 pubmed |
| Cisz M, Lee P, Rietsch A. ExoS controls the cell contact-mediated switch to effector secretion in Pseudomonas aeruginosa. J Bacteriol. 2008;190:2726-38 pubmed |
| Fogel A, Akins M, Krupp A, Stagi M, Stein V, Biederer T. SynCAMs organize synapses through heterophilic adhesion. J Neurosci. 2007;27:12516-30 pubmed |
| Ryabinina O, Subbian E, Iordanov M. D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells. BMC Cell Biol. 2006;7:7 pubmed |
| Cahill A, Herring B, Fox A. Stable silencing of SNAP-25 in PC12 cells by RNA interference. BMC Neurosci. 2006;7:9 pubmed |
| Bao W, Stromblad S. Integrin alphav-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen. J Cell Biol. 2004;167:745-56 pubmed |
| Blumenthal S, Clark G, Roux S. Biochemical and immunological characterization of pea nuclear intermediate filament proteins. Planta. 2004;218:965-75 pubmed |
| Weber I, Gruber C, Steinberg G. A class-V myosin required for mating, hyphal growth, and pathogenicity in the dimorphic plant pathogen Ustilago maydis. Plant Cell. 2003;15:2826-42 pubmed |
| Raff J, Jeffers K, Huang J. The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time. J Cell Biol. 2002;157:1139-49 pubmed |
| Kelso R, Hudson A, Cooley L. Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylation. J Cell Biol. 2002;156:703-13 pubmed |
| Sisson J, Field C, Ventura R, Royou A, Sullivan W. Lava lamp, a novel peripheral golgi protein, is required for Drosophila melanogaster cellularization. J Cell Biol. 2000;151:905-18 pubmed |
| Lin J. Monoclonal antibodies against myofibrillar components of rat skeletal muscle decorate the intermediate filaments of cultured cells. Proc Natl Acad Sci U S A. 1981;78:2335-9 pubmed |
| Blose S, Matsumura F, Lin J. Structure of vimentin 10-nm filaments probed with a monoclonal antibody that recognizes a common antigenic determinant on vimentin and tropomyosin. Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:455-63 pubmed |
| Lin J, Queally S. A monoclonal antibody that recognizes Golgi-associated protein of cultured fibroblast cells. J Cell Biol. 1982;92:108-12 pubmed |
| Tang X, Lancelle S, Hepler P. Fluorescence microscopic localization of actin in pollen tubes: comparison of actin antibody and phalloidin staining. Cell Motil Cytoskeleton. 1989;12:216-24 pubmed |
