Headcase | Developmental Studies Hybridoma Bank HDC U33 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Headcase

catalog :

HDC U33

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HDC U33

reactivity :

fruit fly

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 8

Reference
Djabrayan N, Cruz J, de Miguel C, Franch Marro X, Casanova J. Specification of differentiated adult progenitors via inhibition of endocycle entry in the Drosophila trachea. Cell Rep. 2014;9:859-65 pubmed publisher
Avet Rochex A, Carvajal N, Christoforou C, Yeung K, Maierbrugger K, Hobbs C, et al. Unkempt is negatively regulated by mTOR and uncouples neuronal differentiation from growth control. PLoS Genet. 2014;10:e1004624 pubmed publisher
Loncle N, Williams D. An interaction screen identifies headcase as a regulator of large-scale pruning. J Neurosci. 2012;32:17086-96 pubmed publisher
Steneberg P, Samakovlis C. A novel stop codon readthrough mechanism produces functional Headcase protein in Drosophila trachea. EMBO Rep. 2001;2:593-7 pubmed
Uv A, Roth P, Xylourgidis N, Wickberg A, Cantera R, Samakovlis C. members only encodes a Drosophila nucleoporin required for rel protein import and immune response activation. Genes Dev. 2000;14:1945-57 pubmed
Steneberg P, Hemphälä J, Samakovlis C. Dpp and Notch specify the fusion cell fate in the dorsal branches of the Drosophila trachea. Mech Dev. 1999;87:153-63 pubmed
Steneberg P, Englund C, Kronhamn J, Weaver T, Samakovlis C. Translational readthrough in the hdc mRNA generates a novel branching inhibitor in the drosophila trachea. Genes Dev. 1998;12:956-67 pubmed
Weaver T, White R. headcase, an imaginal specific gene required for adult morphogenesis in Drosophila melanogaster. Development. 1995;121:4149-60 pubmed

product information

Internal ID :

6573

Name :

HDC U33

Depositor Name :

White, R.

Depositor Institution :

Physiology, Development and Neuroscience, University of Cambridge, UK

Date Deposited :

5/25/10

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Headcase

Antigen Species :

drosophila

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

8575315

Collections :

Drosophila antigens

Search Keywords :

White, R., Headcase, drosophila, MIgG1, Drosophila, hdc, CG15532, psg12, AB_10659722, monoclonal, Drosophila antigens, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation

Antigen Molecular Weight :

Predicted: 71 kDa (short) and 117 kDa (full length); Apparent: 70 kDa (short) and 120 kDa (full length)

Gene :

hdc

Alternate Gene Name(s) :

CG15532, psg12

Uniprot ID :

Q9N2M8

Antibody Registry ID :

AB_10659722

Synonyms (Alternate Clone Names) :

U33.7

Immunogen :

Recombinant headcase protein (aa 44-462)

Immunogen Sequence :

Partial protein

Clonality :

Monoclonal

Myeloma Strain :

NSO

Epitope Mapped :

Yes

Epitope Location or Sequence :

aa 44-462

Epitope Map PubMed ID :

8575315

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

yes

Immunohistochemistry Pubmed IDs :

8575315 11463742 9531534 10495279

Immunofluorescence Pubmed IDs :

23197702 25437542 10495279 25210733 10921908

Western Blot Pubmed IDs :

8575315 11463742 9531534

Additional Information :

U33 recognizes the short and full length forms of HDC, but will not recognize the 201 aa B isoform.

DSHB Growth Medium :

RPMI

References (legacy) :

Development 121, 4149-4160.

more info or order :

Developmental Studies Hybridoma Bank product webpage