product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Ganglioside GT1b
catalog :
GT1b-2b
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GT1b-2b
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
citations: 8
Reference |
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Buchwald B, Zhang G, Vogt Eisele A, Zhang W, Ahangari R, Griffin J, et al. Anti-ganglioside antibodies alter presynaptic release and calcium influx. Neurobiol Dis. 2007;28:113-21 pubmed
|
Zhang G, Lopez P, Li C, Mehta N, Griffin J, Schnaar R, et al. Anti-ganglioside antibody-mediated neuronal cytotoxicity and its protection by intravenous immunoglobulin: implications for immune neuropathies. Brain. 2004;127:1085-100 pubmed
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Gong Y, Tagawa Y, Lunn M, Laroy W, Heffer Lauc M, Li C, et al. Localization of major gangliosides in the PNS: implications for immune neuropathies. Brain. 2002;125:2491-506 pubmed
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Schnaar R, Fromholt S, Gong Y, Vyas A, Laroy W, Wayman D, et al. Immunoglobulin G-class mouse monoclonal antibodies to major brain gangliosides. Anal Biochem. 2002;302:276-84 pubmed
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product information
Internal ID :
9409
Name :
GT1b-2b
Depositor Name :
Schnaar, R.L.
Depositor Institution :
Johns Hopkins School of Medicine
Date Deposited :
3/25/14
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
Antigen :
Ganglioside GT1b
Antigen Species :
Bovine
Host Species :
mouse
Isotype :
MIgG2b
Isotype for catalog (legacy) :
IgG2b
Positive Tested Species Reactivity :
Human,Mouse,Rat,Vertebrates
Species Tested (legacy) :
all vertebrates
Initial Publication Pubmed ID :
11878808
Depositor Notes (Special Instructions) :
GT1b-2b recognizes all vertebrate species. Paraformaldehyde fixation works well for immnostaining; avoid most detergents and organic solvents.
Collections :
Cell markers,Human,Neurodevelopment
Search Keywords :
Schnaar, R.L., Ganglioside GT1b, Bovine, MIgG2b, vertebrates/Human/Mouse/Rat, , , AB_2619575, monoclonal, Cell markers/Human/neurodevelopment, Immunohistochemistry/Immunofluorescence/Western Blot/ELISA
Antigen Molecular Weight :
2.15 kDa
Antibody Registry ID :
AB_2619575
Immunogen :
KLH-conjugated bovine brain GT1b
Clonality :
Monoclonal
Myeloma Strain :
P3x653
Epitope Mapped :
Yes
Epitope Location or Sequence :
GT1b
Epitope Map PubMed ID :
11878808
Recommended Applications :
ELISA,Immunofluorescence,Immunohistochemistry,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
11878808 24098718 22206893
Immunofluorescence Pubmed IDs :
12390975 24098718 17720506 26514366
Western Blot Pubmed IDs :
11878808 12390975
ELISA Pubmed IDs :
11878808
FACS Pubmed IDs :
26263924
Pubmed IDs :
14985267
Additional Information :
Gangliosides are glycosphingolipids with one or more sialic acids. Western blot references are for TLC immunooverlay.
DSHB Growth Medium :
Iscove's
References (legacy) :
J. Neurochem. 75, 404-412.; Brain 125, 2491-2506.; Biochim. Biophys. Acta. 1686, 200-208.; J. Histochem. Cytochem. 55(8), 805-812.; PLoS ONE 8(9): e75720. doi:10.1371/journal.pone.0075720.
more info or order :
company information
Developmental Studies Hybridoma Bank
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