product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Glass bottom boat; Protein 60A
catalog :
GBB 3D6-24
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GBB 3D6-24
reactivity :
fruit fly
application :
western blot, immunohistochemistry, immunoprecipitation
citations: 5
Reference
Kim N, Kim S, Nahm M, Kopke D, Kim J, Cho E, et al. BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis. Nat Commun. 2019;10:684 pubmed publisher
Lin H, Boatz J, Krabbendam I, Kodali R, Hou Z, Wetzel R, et al. Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core. Nat Commun. 2017;8:15462 pubmed publisher
Zhou J, Florescu S, Boettcher A, Luo L, Dutta D, Kerr G, et al. Dpp/Gbb signaling is required for normal intestinal regeneration during infection. Dev Biol. 2015;399:189-203 pubmed publisher
James R, Hoover K, Bulgari D, McLaughlin C, Wilson C, Wharton K, et al. Crimpy enables discrimination of presynaptic and postsynaptic pools of a BMP at the Drosophila neuromuscular junction. Dev Cell. 2014;31:586-98 pubmed publisher
Akiyama T, Marques G, Wharton K. A large bioactive BMP ligand with distinct signaling properties is produced by alternative proconvertase processing. Sci Signal. 2012;5:ra28 pubmed publisher
product information
Internal ID :
8194
Name :
GBB 3D6-24
Depositor Name :
Marques, G.
Depositor Institution :
University of Minnesota
Date Deposited :
7/17/12
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
Antigen :
Glass bottom boat; Protein 60A
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG2b
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
22472650
Collections :
Drosophila antigens
Search Keywords :
Marques, Guillermo, Glass bottom boat; Protein 60A, Drosophila, MIgG2a, Drosophila, gbb, 60A; BMP; CG5562; Dm-GBB; TGF-b; TGFbeta-60A; vgr/60A, monoclonal
Antigen Molecular Weight :
Gbb exists in two ligand forms: 15 kDa and 38 kDa.
Gene :
gbb
Alternate Gene Name(s) :
60A; BMP; CG5562; Dm-GBB; TGF-b; TGFbeta-60A; vgr/60A
Uniprot ID :
P27091
Antibody Registry ID :
AB_2618111
Immunogen :
Recombinant protein
Immunogen Sequence :
C-terminal a.a. 426-440
Clonality :
Monoclonal
Myeloma Strain :
P3X63-Ag8.653,P3X63-Ag8
Epitope Mapped :
Yes
Epitope Location or Sequence :
C-terminal a.a 424-440
Recommended Applications :
Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
25453556 25553980
Western Blot Pubmed IDs :
25453556
Immunoprecipitation Pubmed IDs :
25453556
Pubmed IDs :
22472650 28537272
Depositor Growth Medium :
RPMI 1640 10% FCS, Pen/Strep & Fungizone
Additional Information :
RRID:AB_2618111
DSHB Growth Medium :
RPMI
References (legacy) :
Sci. Signal. 5(218), ra28. [DOI: 10.1126/scisignal.2002549].
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US