LAMP-1 (human) | Developmental Studies Hybridoma Bank G1/139/5 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

LAMP-1 (human)

catalog :

G1/139/5

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

G1/139/5

reactivity :

human, pig

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 5a	Adams J, Feuerborn M, Molina J, Wilden A, Adhikari B, Budden T, et al. Autophagy-lysosome pathway alterations and alpha-synuclein up-regulation in the subtype of neuronal ceroid lipofuscinosis, CLN5 disease. Sci Rep. 2019;9:151 pubmed publisher
immunocytochemistry; pig; 1:2; loading ...; fig 4c	Hernaez B, Guerra M, Salas M, Andres G. African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes. PLoS Pathog. 2016;12:e1005595 pubmed publisher
	Olsvik H, Lamark T, Takagi K, Larsen K, Evjen G, Øvervatn A, et al. FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy. J Biol Chem. 2015;290:29361-74 pubmed publisher
	Moran M, Delmiro A, Blazquez A, Ugalde C, Arenas J, Martin M. Bulk autophagy, but not mitophagy, is increased in cellular model of mitochondrial disease. Biochim Biophys Acta. 2014;1842:1059-70 pubmed publisher
	Silvan U, Boiteux C, Sütterlin R, Schroeder U, Mannherz H, Jockusch B, et al. An antiparallel actin dimer is associated with the endocytic pathway in mammalian cells. J Struct Biol. 2012;177:70-80 pubmed publisher
	Müntener K, Zwicky R, Csucs G, Rohrer J, Baici A. Exon skipping of cathepsin B: mitochondrial targeting of a lysosomal peptidase provokes cell death. J Biol Chem. 2004;279:41012-7 pubmed
	Müntener K, Zwicky R, Csucs G, Baici A. The alternative use of exons 2 and 3 in cathepsin B mRNA controls enzyme trafficking and triggers nuclear fragmentation in human cells. Histochem Cell Biol. 2003;119:93-101 pubmed
	Rohrer J, Schweizer A, Russell D, Kornfeld S. The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane. J Cell Biol. 1996;132:565-76 pubmed
	Schweizer A, Fransen J, Bachi T, Ginsel L, Hauri H. Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus. J Cell Biol. 1988;107:1643-53 pubmed

product information

Internal ID :

6386

Name :

G1/139/5

Depositor Name :

Hauri, H.-P.

Depositor Institution :

University of Basel, Switzerland

Date Deposited :

2/8/10

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

LAMP-1 (human)

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Human

Species Tested (legacy) :

human

Initial Publication Pubmed ID :

3182932

Collections :

CD antigens,Cell signaling,Human

Search Keywords :

Hauri, H.-P., LAMP-1 (human), Human, MIgG1, Human, LAMP1, CD107a, LGP120, LAMPA, AB_10659721, monoclonal, Human/Cell signaling/Cluster Determinant antigens, Immunoprecipitation/Western Blot/Immunofluorescence

Antigen Molecular Weight :

Predicted: 42 kDa; Apparent: 120 kDa

Gene :

LAMP1

Alternate Gene Name(s) :

CD107a, LGP120, LAMPA

Uniprot ID :

P11279

Antibody Registry ID :

AB_10659721

Synonyms (Alternate Clone Names) :

G1/139

Immunogen :

Purified Golgi membranes isolated from Caco-2 cells

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Myeloma Strain :

PA1

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

yes

Immunofluorescence Pubmed IDs :

3182932 26468287 21970948 12610728

Western Blot Pubmed IDs :

24704045 8647888 15262981

DSHB Growth Medium :

Iscove's

References (legacy) :

J. Cell. Biol. 107, 1643-1653.

more info or order :

Developmental Studies Hybridoma Bank product webpage