product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
elav Drosophila protein
catalog :
Elav-9F8A9
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Elav-9F8A9
reactivity :
fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 90
Published Application/Species/Sample/Dilution | Reference |
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Ida H, Suyari O, Shimamura M, Tien Tai T, Yamaguchi M, Taketani S. Genetic link between heme oxygenase and the signaling pathway of DNA damage in Drosophila melanogaster. Tohoku J Exp Med. 2013;231:117-25 pubmed
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Thorne N, Amrein H. Atypical expression of Drosophila gustatory receptor genes in sensory and central neurons. J Comp Neurol. 2008;506:548-68 pubmed
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Berger C, Renner S, Lüer K, Technau G. The commonly used marker ELAV is transiently expressed in neuroblasts and glial cells in the Drosophila embryonic CNS. Dev Dyn. 2007;236:3562-8 pubmed
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Laurencon A, Dubruille R, Efimenko E, Grenier G, Bissett R, Cortier E, et al. Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species. Genome Biol. 2007;8:R195 pubmed
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Bader R, Colomb J, Pankratz B, Schröck A, Stocker R, Pankratz M. Genetic dissection of neural circuit anatomy underlying feeding behavior in Drosophila: distinct classes of hugin-expressing neurons. J Comp Neurol. 2007;502:848-56 pubmed
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Ryoo H, Domingos P, Kang M, Steller H. Unfolded protein response in a Drosophila model for retinal degeneration. EMBO J. 2007;26:242-52 pubmed
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Kuraishi T, Manaka J, Kono M, Ishii H, Yamamoto N, Koizumi K, et al. Identification of calreticulin as a marker for phagocytosis of apoptotic cells in Drosophila. Exp Cell Res. 2007;313:500-10 pubmed
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Sullivan J, Benton J, Sandeman D, Beltz B. Adult neurogenesis: a common strategy across diverse species. J Comp Neurol. 2007;500:574-84 pubmed
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Gallagher C, Knoblich J. The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell. 2006;11:641-53 pubmed
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Shafer O, Helfrich Forster C, Renn S, Taghert P. Reevaluation of Drosophila melanogaster's neuronal circadian pacemakers reveals new neuronal classes. J Comp Neurol. 2006;498:180-93 pubmed
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Hennig K, Colombani J, Neufeld T. TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. J Cell Biol. 2006;173:963-74 pubmed
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Fishilevich E, Domingos A, Asahina K, Naef F, Vosshall L, Louis M. Chemotaxis behavior mediated by single larval olfactory neurons in Drosophila. Curr Biol. 2005;15:2086-96 pubmed
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LeComte M, Wesley U, Mok L, Shepherd A, Wesley C. Evidence for the involvement of dominant-negative Notch molecules in the normal course of Drosophila development. Dev Dyn. 2006;235:411-26 pubmed
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Voas M, Rebay I. The novel plant homeodomain protein rhinoceros antagonizes Ras signaling in the Drosophila eye. Genetics. 2003;165:1993-2006 pubmed
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Dow L, Brumby A, Muratore R, Coombe M, Sedelies K, Trapani J, et al. hScrib is a functional homologue of the Drosophila tumour suppressor Scribble. Oncogene. 2003;22:9225-30 pubmed
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Sasamura T, Sasaki N, Miyashita F, Nakao S, Ishikawa H, Ito M, et al. neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. Development. 2003;130:4785-95 pubmed
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Overstreet E, Chen X, Wendland B, Fischer J. Either part of a Drosophila epsin protein, divided after the ENTH domain, functions in endocytosis of delta in the developing eye. Curr Biol. 2003;13:854-60 pubmed
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Cyran S, Buchsbaum A, Reddy K, Lin M, Glossop N, Hardin P, et al. vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock. Cell. 2003;112:329-41 pubmed
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Kidd S, Lieber T. Furin cleavage is not a requirement for Drosophila Notch function. Mech Dev. 2002;115:41-51 pubmed
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Nakamura M, Baldwin D, Hannaford S, Palka J, Montell C. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. J Neurosci. 2002;22:3463-72 pubmed
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Goto S, Taniguchi M, Muraoka M, Toyoda H, Sado Y, Kawakita M, et al. UDP-sugar transporter implicated in glycosylation and processing of Notch. Nat Cell Biol. 2001;3:816-22 pubmed
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Nagaso H, Murata T, Day N, Yokoyama K. Simultaneous detection of RNA and protein by in situ hybridization and immunological staining. J Histochem Cytochem. 2001;49:1177-82 pubmed
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Rusten T, Cantera R, Urban J, Technau G, Kafatos F, Barrio R. Spalt modifies EGFR-mediated induction of chordotonal precursors in the embryonic PNS of Drosophila promoting the development of oenocytes. Development. 2001;128:711-22 pubmed
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Vosshall L, Wong A, Axel R. An olfactory sensory map in the fly brain. Cell. 2000;102:147-59 pubmed
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Nagel A, Maier D, Preiss A. Su(H)-independent activity of hairless during mechano-sensory organ formation in Drosophila. Mech Dev. 2000;94:3-12 pubmed
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Kavaler J, Fu W, Duan H, Noll M, Posakony J. An essential role for the Drosophila Pax2 homolog in the differentiation of adult sensory organs. Development. 1999;126:2261-72 pubmed
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Lesokhin A, Yu S, Katz J, Baker N. Several levels of EGF receptor signaling during photoreceptor specification in wild-type, Ellipse, and null mutant Drosophila. Dev Biol. 1999;205:129-44 pubmed
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Jacobsen T, Brennan K, Arias A, Muskavitch M. Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila. Development. 1998;125:4531-40 pubmed
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Simon A, Boquet I, Synguelakis M, Preat T. The Drosophila putative kinase linotte (derailed) prevents central brain axons from converging on a newly described interhemispheric ring. Mech Dev. 1998;76:45-55 pubmed
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Baker N, Yu S, Han D. Evolution of proneural atonal expression during distinct regulatory phases in the developing Drosophila eye. Curr Biol. 1996;6:1290-301 pubmed
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O Neill E, Rebay I, Tjian R, Rubin G. The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell. 1994;78:137-47 pubmed
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Ma C, Moses K. Wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye. Development. 1995;121:2279-89 pubmed
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product information
Internal ID :
1653
Name :
Elav-9F8A9
Depositor Name :
Rubin, Gerald M.
Depositor Institution :
HHMI / Janelia Farm Research
Date Deposited :
8/31/94
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
elav Drosophila protein
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Crayfish,Drosophila,Tsetse fly,Xenopus
Initial Publication Pubmed ID :
8033205 7671795
Depositor Notes (Special Instructions) :
Fusion: 3/6/92. elav-9F8A9 is is a marker for most cells in the central and peripheral nervous system, at all stages of development, once they have differentiated into a neuron.
Collections :
Cell markers,Drosophila antigens,Neurodevelopment,Nucleus
Search Keywords :
Rubin, Gerald M., elav Drosophila protein, Drosophila, MIgG1, kappa light chain, Drosophila/Crayfish/Xenopus, elav, embryonic lethal abnormal vision; EC7; EG:65F1.2, AB_528217 AB_2314363 AB_2314364, monoclonal, Drosophila antigens/Neurodevelopment/Nucleus/Cell markers, Immunohistochemistry/Immunofluorescence/Western Blot/Immunoprecipitation/FFPE
Antigen Molecular Weight :
50kDa
Gene :
elav
Alternate Gene Name(s) :
embryonic lethal abnormal vision; EC7; EG:65F1.2
Uniprot ID :
P16914
Antibody Registry ID :
AB_528217
Immunogen :
Recombinant total protein fused to the first 260 aa of phage T7 gene 10.
Immunogen Sequence :
Total protein
Clonality :
Monoclonal
Myeloma Strain :
P3x63Ag8.653
Epitope Mapped :
No
Recommended Applications :
FFPE,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunohistochemistry Pubmed IDs :
7671795 9767102 11533661 12049766 20550966 16331645 11511686 8939576 9882502 9778511 27095495 11171396 20011537 30875383
Immunofluorescence Pubmed IDs :
24632433 25006677 25305076 24803653 25393278 24928275 24863968 25151265 24706779 24291519 24598157 19749760 14704181 16332533 17436293 12747835 14681682 12581523 19294644 17994541 23550139 17084357 19757495 11978823 17120293 19824090 17170705 22580825 20682638 17137576 12917292 24126234 20230745 23886579 22648855 23846225 10207150 10943836 27143646 10842054 26942723 22649083 19662164 27105580 27442438 29249285 26762251 29324767 30571694 27913291 31353186 31332509 31327508
Western Blot Pubmed IDs :
17994541 24803653 20209138
Immunoprecipitation Pubmed IDs :
24803653 23666178
FFPE Pubmed IDs :
24863968
Depositor Growth Medium :
Iscove's
Additional Information :
The elav protein binds RNA and is involved in RNA processing. elav is a pan-neuronal marker (nuclear marker for post mitotic neurons) and is often used to contrast staining obtained with 8D12 anti-Repo, a marker of glial cells. This mAb works on WB, but the rat version Rat-Elav-7E8A10 anti-elav may work better [PMID 17994541].
DSHB Growth Medium :
Iscove's
References (legacy) :
Cell 78, 137-147.; Development 125, 4531-4540.; Development 126, 2261-2272.; Dev. Biol. 205, 129-144.; Mech. Dev. 94, 3-12.; Cell 102, 147-159.; Development 128, 711-722.; Nature Cell Biol. 3(9), 816-822.; J. Histochem. Cytochem. 49(9), 1177-1182.
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Developmental Studies Hybridoma Bank
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