product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Tubulin, beta
catalog :
E7
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E7
reactivity :
Octopus bimaculoides, African green monkey, human, mouse, rat, pig, fruit fly, common platanna
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 162
Published Application/Species/Sample/DilutionReference
  • western blot; African green monkey; 1:1000; loading ...; fig 1b
Gorla M, Santiago C, Chaudhari K, Layman A, Oliver P, Bashaw G. Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019;26:3298-3312.e4 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4h
  • western blot; human; 1:1000; loading ...; fig 1f
Beug S, Cheung H, Sanda T, St Jean M, Beauregard C, Mamady H, et al. The transcription factor SP3 drives TNF-α expression in response to Smac mimetics. Sci Signal. 2019;12: pubmed publisher
  • western blot; human; loading ...; fig 3b
Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed publisher
  • immunohistochemistry; fruit fly; fig 3a
Takács Z, Jankovics F, Vilmos P, Lenart P, Röper K, Erdelyi M. The spectraplakin Short stop is an essential microtubule regulator involved in epithelial closure in Drosophila. J Cell Sci. 2017;130:712-724 pubmed publisher
  • immunocytochemistry; mouse; fig 1a
Wakatsuki S, Tokunaga S, Shibata M, Araki T. GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration. J Cell Biol. 2017;216:477-493 pubmed publisher
  • western blot; fruit fly; 1:20,000; fig s3e
Monyak R, Emerson D, Schoenfeld B, Zheng X, Chambers D, Rosenfelt C, et al. Insulin signaling misregulation underlies circadian and cognitive deficits in a Drosophila fragile X model. Mol Psychiatry. 2017;22:1140-1148 pubmed publisher
  • western blot; fruit fly; 1:2000; fig 4
Chanu S, Sarkar S. Targeted Downregulation of dMyc Suppresses Pathogenesis of Human Neuronal Tauopathies in Drosophila by Limiting Heterochromatin Relaxation and Tau Hyperphosphorylation. Mol Neurobiol. 2017;54:2706-2719 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 11a
Moyle L, Blanc E, Jaka O, Prueller J, Banerji C, Tedesco F, et al. Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. elife. 2016;5: pubmed publisher
  • western blot; fruit fly; 1:10,000; fig 3
Liu M, Li Y, Liu A, Li R, Su Y, Du J, et al. The exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development. elife. 2016;5: pubmed publisher
  • western blot; fruit fly; 1:1000; fig 2
Backhaus P, Langenhan T, Neuser K. Effects of transgenic expression of botulinum toxins in Drosophila. J Neurogenet. 2016;30:22-31 pubmed publisher
  • western blot; human; fig s4
Broadus M, Chen T, Neitzel L, Ng V, Jodoin J, Lee L, et al. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Rep. 2016;15:1920-9 pubmed publisher
  • western blot; pig; 1:500; fig 2
Mukherjee A, Garrels W, Talluri T, Tiedemann D, Bosze Z, Ivics Z, et al. Expression of Active Fluorophore Proteins in the Milk of Transgenic Pigs Bypassing the Secretory Pathway. Sci Rep. 2016;6:24464 pubmed publisher
  • western blot; mouse; fig 2
Cong X, Doering J, Mázala D, Chin E, Grange R, Jiang H. The SH3 and cysteine-rich domain 3 (Stac3) gene is important to growth, fiber composition, and calcium release from the sarcoplasmic reticulum in postnatal skeletal muscle. Skelet Muscle. 2016;6:17 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 3
  • immunohistochemistry; common platanna; 1:200; fig s8
Petridou N, Skourides P. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016;7:10899 pubmed publisher
  • immunocytochemistry; African green monkey; fig 2
Xu J, Wang N, Luo J, Xia J. Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons. Sci Rep. 2016;6:20924 pubmed publisher
  • western blot; human; fig 1
Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed publisher
  • western blot; human; 1:2000; fig 7
Kraft L, Manral P, Dowler J, Kenworthy A. Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic. 2016;17:369-99 pubmed publisher
  • western blot; rat; fig 1
Fan S, Numata Y, Numata M. Endosomal Na+/H+ exchanger NHE5 influences MET recycling and cell migration. Mol Biol Cell. 2016;27:702-15 pubmed publisher
  • western blot; rat; 1:5000
Pathak T, Agrawal T, Richhariya S, Sadaf S, Hasan G. Store-Operated Calcium Entry through Orai Is Required for Transcriptional Maturation of the Flight Circuit in Drosophila. J Neurosci. 2015;35:13784-99 pubmed publisher
  • western blot; human; fig 7b
Miles W, Lepesant J, Bourdeaux J, Texier M, Kerenyi M, Nakakido M, et al. The LSD1 Family of Histone Demethylases and the Pumilio Posttranscriptional Repressor Function in a Complex Regulatory Feedback Loop. Mol Cell Biol. 2015;35:4199-211 pubmed publisher
  • western blot; mouse; 1:1000
Sun D, Buttitta L. Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila. Development. 2015;142:3033-45 pubmed publisher
  • western blot; fruit fly; 1:10,000; fig S4
Chakraborty R, Li Y, Zhou L, Golic K. Corp Regulates P53 in Drosophila melanogaster via a Negative Feedback Loop. PLoS Genet. 2015;11:e1005400 pubmed publisher
  • immunocytochemistry; fruit fly; 1:100; fig 4.2
Evans T, Santiago C, Arbeille E, Bashaw G. Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons. elife. 2015;4:e08407 pubmed publisher
  • western blot; fruit fly; 1:700
Niehues S, Bussmann J, Steffes G, Erdmann I, Köhrer C, Sun L, et al. Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nat Commun. 2015;6:7520 pubmed publisher
  • immunocytochemistry; Octopus bimaculoides; loading ...; fig 4d
Ramirez M, Oakley T. Eye-independent, light-activated chromatophore expansion (LACE) and expression of phototransduction genes in the skin of Octopus bimaculoides. J Exp Biol. 2015;218:1513-20 pubmed publisher
  • immunocytochemistry; mouse; 1:300
Figeac N, Zammit P. Coordinated action of Axin1 and Axin2 suppresses β-catenin to regulate muscle stem cell function. Cell Signal. 2015;27:1652-65 pubmed publisher
  • western blot; human
Alpay M, Backman L, Cheng X, Dukel M, Kim W, Ai L, et al. Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling. Breast Cancer Res Treat. 2015;151:75-87 pubmed publisher
  • western blot; fruit fly; 1:700; fig 1
Frickenhaus M, Wagner M, Mallik M, Catinozzi M, Storkebaum E. Highly efficient cell-type-specific gene inactivation reveals a key function for the Drosophila FUS homolog cabeza in neurons. Sci Rep. 2015;5:9107 pubmed publisher
  • western blot; fruit fly; 1:1000; fig 4
Escobar D, Desai R, Ishiyama N, Folmsbee S, Novak M, Flozak A, et al. α-Catenin phosphorylation promotes intercellular adhesion through a dual-kinase mechanism. J Cell Sci. 2015;128:1150-65 pubmed publisher
  • immunocytochemistry; fruit fly; 1:50; loading ...; fig 2a
Pflanz R, Voigt A, Yakulov T, Jäckle H. Drosophila gene tao-1 encodes proteins with and without a Ste20 kinase domain that affect cytoskeletal architecture and cell migration differently. Open Biol. 2015;5:140161 pubmed publisher
  • western blot; human; fig 2
Liang K, Gao X, Gilmore J, Florens L, Washburn M, Smith E, et al. Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing. Mol Cell Biol. 2015;35:928-38 pubmed publisher
  • western blot; mouse; 1:5000
Renoux A, Carducci N, Ahmady A, Todd P. Fragile X mental retardation protein expression in Alzheimer's disease. Front Genet. 2014;5:360 pubmed publisher
  • western blot; mouse
Moutaoufik M, El Fatimy R, Nassour H, Gareau C, Lang J, Tanguay R, et al. UVC-induced stress granules in mammalian cells. PLoS ONE. 2014;9:e112742 pubmed publisher
  • western blot; human
Raman N, Nayak A, Muller S. mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol. 2014;34:4474-84 pubmed publisher
  • western blot; human
Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T. Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop. J Biol Chem. 2014;289:32845-57 pubmed publisher
  • western blot; mouse; fig 1
Han M, Hu Z, Chen C, Chen Y, Gucek M, Li Z, et al. Dysbindin-associated proteome in the p2 synaptosome fraction of mouse brain. J Proteome Res. 2014;13:4567-80 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Can T, Faas L, Ashford D, Dowle A, Thomas J, O Toole P, et al. Proteomic analysis of laser capture microscopy purified myotendinous junction regions from muscle sections. Proteome Sci. 2014;12:25 pubmed publisher
  • western blot; human
Schneppenheim J, Hüttl S, Kruchen A, Fluhrer R, Müller I, Saftig P, et al. Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells. Biochem Biophys Res Commun. 2014;451:48-53 pubmed publisher
  • western blot; fruit fly; 1:1000
Li L, Tian X, Zhu M, Bulgari D, Böhme M, Goettfert F, et al. Drosophila Syd-1, liprin-α, and protein phosphatase 2A B' subunit Wrd function in a linear pathway to prevent ectopic accumulation of synaptic materials in distal axons. J Neurosci. 2014;34:8474-87 pubmed publisher
  • western blot; mouse; fig 5
Wu M, Li C, Zhu G, Wang Y, Jules J, Lu Y, et al. Deletion of core-binding factor β (Cbfβ) in mesenchymal progenitor cells provides new insights into Cbfβ/Runxs complex function in cartilage and bone development. Bone. 2014;65:49-59 pubmed publisher
  • western blot; mouse
  • western blot; rat
Wakatsuki S, Araki T, Sehara Fujisawa A. Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing ?5 ?1 integrin-ErbB2-focal adhesion kinase complex formation. Genes Cells. 2014;19:66-77 pubmed publisher
  • western blot; fruit fly; 1:10
Koppen T, Weckmann A, Muller S, Staubach S, Bloch W, Dohmen R, et al. Proteomics analyses of microvesicles released by Drosophila Kc167 and S2 cells. Proteomics. 2011;11:4397-410 pubmed publisher
  • immunohistochemistry; rat; 1:1000
Levendusky M, Basle J, Chang S, Mandalaywala N, Voigt J, DEARBORN R. Expression and regulation of vitamin D3 upregulated protein 1 (VDUP1) is conserved in mammalian and insect brain. J Comp Neurol. 2009;517:581-600 pubmed publisher
Barčák D, Yoneva A, Sehadova H, Oros M, Gustinelli A, Kuchta R. Complex insight on microanatomy of larval "human broad tapeworm" Dibothriocephalus latus (Cestoda: Diphyllobothriidea). Parasit Vectors. 2019;12:408 pubmed publisher
Kreymerman A, Buickians D, Nahmou M, Tran T, Galvão J, Wang Y, et al. MTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury Responses. Sci Rep. 2019;9:10669 pubmed publisher
Feng X, Wang Z, Wang F, Lu T, Xu J, Ma X, et al. Dual function of VGLL4 in muscle regeneration. EMBO J. 2019;38:e101051 pubmed publisher
Sun T, Song Y, Dai J, Mao D, Ma M, Ni J, et al. Spectraplakin Shot Maintains Perinuclear Microtubule Organization in Drosophila Polyploid Cells. Dev Cell. 2019;49:731-747.e7 pubmed publisher
Ignarski M, Rill C, Kaiser R, Kaldirim M, Neuhaus R, Esmaillie R, et al. The RNA-Protein Interactome of Differentiated Kidney Tubular Epithelial Cells. J Am Soc Nephrol. 2019;30:564-576 pubmed publisher
Zhao Z, Wang L, Volk A, Birch N, Stoltz K, Bartom E, et al. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia. Genes Dev. 2019;33:61-74 pubmed publisher
Zhang H, Xie H, Wang W, Wang Z, Tao Y. Pharmacology of the giant panda (Ailuropoda melanoleuca) melanocortin-3 receptor. Gen Comp Endocrinol. 2019;277:73-81 pubmed publisher
Kline A, Curry T, Lewellyn L. The Misshapen kinase regulates the size and stability of the germline ring canals in the Drosophila egg chamber. Dev Biol. 2018;440:99-112 pubmed publisher
Chen Q, Huang L, Pan D, Zhu L, Wang Y. Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis. Cell Rep. 2018;22:2860-2872 pubmed publisher
Ashe S, Malhotra V, Raghu P. Protein kinase D regulates metabolism and growth by controlling secretion of insulin like peptide. Dev Biol. 2018;434:175-185 pubmed publisher
Cheong H, VanBerkum M. Long disordered regions of the C-terminal domain of Abelson tyrosine kinase have specific and additive functions in regulation and axon localization. PLoS ONE. 2017;12:e0189338 pubmed publisher
Devambez I, Van Dijk J, Benlefki S, Layalle S, Grau Y, Rogowski K, et al. Identification of DmTTLL5 as a Major Tubulin Glutamylase in the Drosophila Nervous System. Sci Rep. 2017;7:16254 pubmed publisher
Court H, Ahearn I, Amoyel M, Bach E, Philips M. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. J Cell Biol. 2017;216:4165-4182 pubmed publisher
Huet Calderwood C, Rivera Molina F, Iwamoto D, Kromann E, Toomre D, Calderwood D. Novel ecto-tagged integrins reveal their trafficking in live cells. Nat Commun. 2017;8:570 pubmed publisher
Apara A, Galvão J, Wang Y, Blackmore M, Trillo A, Iwao K, et al. KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS. J Neurosci. 2017;37:9632-9644 pubmed publisher
Wu M, Wang Y, Shao J, Wang J, Chen W, Li Y. Cbfβ governs osteoblast-adipocyte lineage commitment through enhancing β-catenin signaling and suppressing adipogenesis gene expression. Proc Natl Acad Sci U S A. 2017;114:10119-10124 pubmed publisher
Brasher M, Martynowicz D, Grafinger O, Hucik A, Shanks Skinner E, Uniacke J, et al. Interaction of Munc18c and syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumor cells. J Biol Chem. 2017;292:16199-16210 pubmed publisher
Eritano A, Altamirano A, Beyeler S, Gaytan N, Velasquez M, Riggs B. The endoplasmic reticulum is partitioned asymmetrically during mitosis before cell fate selection in proneuronal cells in the early Drosophila embryo. Mol Biol Cell. 2017;28:1530-1538 pubmed publisher
Agabiti S, Li J, Wiemer A. Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation. Cell Death Dis. 2017;8:e2678 pubmed publisher
Balashova O, Visina O, Borodinsky L. Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation. Development. 2017;144:1518-1530 pubmed publisher
Hindle S, Hebbar S, Schwudke D, Elliott C, Sweeney S. A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline. Neurobiol Dis. 2017;98:77-87 pubmed publisher
Ali T, Kruger M, Bhuju S, Jarek M, Bartkuhn M, Renkawitz R. Chromatin binding of Gcn5 in Drosophila is largely mediated by CP190. Nucleic Acids Res. 2017;45:2384-2395 pubmed publisher
D Brot A, Kurtz P, Regan E, Jakubowski B, Abrams J. A platform for interrogating cancer-associated p53 alleles. Oncogene. 2017;36:286-291 pubmed publisher
Grabe G, Zhang Y, Przydacz M, Rolhion N, Yang Y, Pruneda J, et al. The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence. J Biol Chem. 2016;291:25853-25863 pubmed
Hong S, Choi K. Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences. Nat Commun. 2016;7:12988 pubmed publisher
Jarosch I, Gehlert S, Jacko D, Koczulla R, Wencker M, Welte T, et al. Different Training-Induced Skeletal Muscle Adaptations in COPD Patients with and without Alpha-1 Antitrypsin Deficiency. Respiration. 2016;92:339-347 pubmed
Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
Rodrigues F, Shao W, Harris T. The Arf GAP Asap promotes Arf1 function at the Golgi for cleavage furrow biosynthesis in Drosophila. Mol Biol Cell. 2016;27:3143-3155 pubmed
Zhou M, Wiener H, Su W, Zhou Y, Liot C, Ahearn I, et al. VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking. J Cell Biol. 2016;214:445-58 pubmed publisher
Barekat A, Gonzalez A, Mauntz R, Kotzebue R, Molina B, El Mecharrafie N, et al. Using Drosophila as an integrated model to study mild repetitive traumatic brain injury. Sci Rep. 2016;6:25252 pubmed publisher
Chopra A, Bond M, Bleiler M, Yeagley M, Wright D, Giardina C. Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301. PLoS ONE. 2016;11:e0153818 pubmed publisher
Jain S, Welshhans K. Netrin-1 induces local translation of down syndrome cell adhesion molecule in axonal growth cones. Dev Neurobiol. 2016;76:799-816 pubmed publisher
Lin J, Wang C, Yang C, Fu S, Redies C. Pax3 and Pax7 interact reciprocally and regulate the expression of cadherin-7 through inducing neuron differentiation in the developing chicken spinal cord. J Comp Neurol. 2016;524:940-62 pubmed publisher
Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, et al. Rac1 Regulates Endometrial Secretory Function to Control Placental Development. PLoS Genet. 2015;11:e1005458 pubmed publisher
Babic M, Russo G, Wellington A, Sangston R, Gonzalez M, Zinsmaier K. Miro's N-terminal GTPase domain is required for transport of mitochondria into axons and dendrites. J Neurosci. 2015;35:5754-71 pubmed publisher
Liachko N, McMillan P, Strovas T, Loomis E, Greenup L, Murrell J, et al. The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43. PLoS Genet. 2014;10:e1004803 pubmed publisher
Wang W, Anderson L, Nicklay J, Chen H, Gamble M, Shabanowitz J, et al. Phosphorylation and arginine methylation mark histone H2A prior to deposition during Xenopus laevis development. Epigenetics Chromatin. 2014;7:22 pubmed publisher
Werner M, Mitchell J, Putzbach W, Bacon E, Kim S, Mitchell B. Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1. J Cell Biol. 2014;206:367-76 pubmed publisher
Chen X, Quan Y, Wang H, Luo H. Trehalase regulates neuroepithelial stem cell maintenance and differentiation in the Drosophila optic lobe. PLoS ONE. 2014;9:e101433 pubmed publisher
Kummer M, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, et al. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. J Neurosci. 2014;34:8845-54 pubmed publisher
Karlsson A, Washington J, Dimitrova V, Hooper C, Shekhtman A, Bakowska J. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol Biol Cell. 2014;25:1355-65 pubmed publisher
Walker J, Gouzi J, Long J, Huang S, Maher R, Xia H, et al. Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency. PLoS Genet. 2013;9:e1003958 pubmed publisher
Roberts B, Reddy R, Wahl J. Stratifin (14-3-3 σ) limits plakophilin-3 exchange with the desmosomal plaque. PLoS ONE. 2013;8:e77012 pubmed publisher
Blasius T, Reed N, Slepchenko B, Verhey K. Recycling of kinesin-1 motors by diffusion after transport. PLoS ONE. 2013;8:e76081 pubmed publisher
Agrawal T, Sadaf S, Hasan G. A genetic RNAi screen for IP₃/Ca²⁺ coupled GPCRs in Drosophila identifies the PdfR as a regulator of insect flight. PLoS Genet. 2013;9:e1003849 pubmed publisher
Xie H, Cammarato A, Rajasekaran N, Zhang H, Suggs J, Lin H, et al. The NADPH metabolic network regulates human ?B-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster. PLoS Genet. 2013;9:e1003544 pubmed publisher
Thiel K, Heier C, Haberl V, Thul P, Oberer M, Lass A, et al. The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage. J Cell Sci. 2013;126:2198-212 pubmed publisher
Zhang K, Li Z, Jaiswal M, Bayat V, Xiong B, Sandoval H, et al. The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit. J Cell Biol. 2013;200:807-20 pubmed publisher
Sen A, Damm V, Cox R. Drosophila clueless is highly expressed in larval neuroblasts, affects mitochondrial localization and suppresses mitochondrial oxidative damage. PLoS ONE. 2013;8:e54283 pubmed publisher
Iliff A, Renoux A, Krans A, Usdin K, Sutton M, Todd P. Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice. Hum Mol Genet. 2013;22:1180-92 pubmed publisher
Xu S, Hafer N, Agunwamba B, Schedl P. The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster. PLoS Genet. 2012;8:e1003079 pubmed publisher
Bolkan B, Triphan T, Kretzschmar D. β-secretase cleavage of the fly amyloid precursor protein is required for glial survival. J Neurosci. 2012;32:16181-92 pubmed publisher
Chen J, Nekrasova O, Patel D, Klessner J, Godsel L, Koetsier J, et al. The C-terminal unique region of desmoglein 2 inhibits its internalization via tail-tail interactions. J Cell Biol. 2012;199:699-711 pubmed publisher
Soppina V, Herbstman J, Skiniotis G, Verhey K. Luminal localization of ?-tubulin K40 acetylation by cryo-EM analysis of fab-labeled microtubules. PLoS ONE. 2012;7:e48204 pubmed publisher
Lee J, Fischer J. Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signaling. PLoS ONE. 2012;7:e46357 pubmed publisher
Manceau V, Kremmer E, Nabel E, Maucuer A. The protein kinase KIS impacts gene expression during development and fear conditioning in adult mice. PLoS ONE. 2012;7:e43946 pubmed publisher
Gonda R, Garlena R, Stronach B. Drosophila heat shock response requires the JNK pathway and phosphorylation of mixed lineage kinase at a conserved serine-proline motif. PLoS ONE. 2012;7:e42369 pubmed publisher
Wang J, Beck E, McCabe B. A modular toolset for recombination transgenesis and neurogenetic analysis of Drosophila. PLoS ONE. 2012;7:e42102 pubmed publisher
Vourekas A, Zheng Q, Alexiou P, Maragkakis M, Kirino Y, Gregory B, et al. Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis. Nat Struct Mol Biol. 2012;19:773-81 pubmed publisher
Fong J, Kells R, Gumpert A, Marzillier J, Davidson M, Falk M. Internalized gap junctions are degraded by autophagy. Autophagy. 2012;8:794-811 pubmed publisher
Lange S, Perera S, Teh P, Chen J. Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover. Mol Biol Cell. 2012;23:2490-504 pubmed publisher
Ben Aissa M, April M, Bergeron L, Perreault J, Levesque G. Silencing of amyloid precursor protein expression using a new engineered delta ribozyme. Int J Alzheimers Dis. 2012;2012:947147 pubmed publisher
Lelièvre E, Plestant C, Boscher C, Wolff E, Mège R, Birbes H. N-cadherin mediates neuronal cell survival through Bim down-regulation. PLoS ONE. 2012;7:e33206 pubmed publisher
Fatima R. Drosophila Dynein intermediate chain gene, Dic61B, is required for spermatogenesis. PLoS ONE. 2011;6:e27822 pubmed publisher
Braun T, Zhu X, Szumowski M, Scott G, Grossberg A, Levasseur P, et al. Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic-pituitary-adrenal axis. J Exp Med. 2011;208:2449-63 pubmed publisher
Wakatsuki S, Saitoh F, Araki T. ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation. Nat Cell Biol. 2011;13:1415-23 pubmed publisher
Leventis P, Da Sylva T, Rajwans N, Wasiak S, McPherson P, Boulianne G. Liquid facets-related (lqfR) is required for egg chamber morphogenesis during Drosophila oogenesis. PLoS ONE. 2011;6:e25466 pubmed publisher
Bhogal B, Jepson J, Savva Y, Pepper A, Reenan R, Jongens T. Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. Nat Neurosci. 2011;14:1517-24 pubmed publisher
Tan G, Chiu C, Garchow B, METZLER D, Diamond S, Kiriakidou M. Small molecule inhibition of RISC loading. ACS Chem Biol. 2012;7:403-10 pubmed publisher
Olsan E, Mukherjee S, Wulkersdorfer B, Shillingford J, Giovannone A, Todorov G, et al. Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease. Proc Natl Acad Sci U S A. 2011;108:18067-72 pubmed publisher
McGurk L, Bonini N. Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila. Hum Mol Genet. 2012;21:76-84 pubmed publisher
Derfoul A, Juan A, Difilippantonio M, Palanisamy N, Ried T, Sartorelli V. Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis. 2011;32:1607-14 pubmed publisher
Beerman R, Jongens T. A non-canonical start codon in the Drosophila fragile X gene yields two functional isoforms. Neuroscience. 2011;181:48-66 pubmed publisher
Vavlitou N, Sargiannidou I, Markoullis K, Kyriacou K, Scherer S, Kleopa K. Axonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie Tooth neuropathy. J Neuropathol Exp Neurol. 2010;69:945-58 pubmed publisher
Smith R, Lerch Haner J, Pardinas J, Buchser W, Bixby J, Lemmon V. Transcriptional profiling of intrinsic PNS factors in the postnatal mouse. Mol Cell Neurosci. 2011;46:32-44 pubmed publisher
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product information
Internal ID :
2887
Name :
E7
Depositor Name :
Klymkowsky, M.
Depositor Institution :
MCD Biology, University of Colorado, Boulder
Date Deposited :
11/1/88
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Tubulin, beta
Antigen Species :
Chlamydomonas
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Chlamydomonas,Drosophila,Flatworm,Giant panda,Human,Kangaroo Rat,Mouse,Xenopus
Species Tested (legacy) :
reacts with Chlamydomonas , Drosophila, Xenpous, mouse, kangaroo rat, human cells, planaria
Initial Publication Pubmed ID :
2680681
Depositor Notes (Special Instructions) :
Stains methanol fixed cells.
Collections :
C. elegans,Cytoskeleton,Drosophila antigens,Human,Microbe antibodies,Xenopus
Search Keywords :
Klymkowsky, Michael, Tubulin, beta, Chylamydomonas, MIgG1, Chlamydomonas/Drosophila/Flatworm/Human/Kangaroo Rat/Mouse/Xenopus, Tubb, , AB_2315513, Monoclonal
Antigen Molecular Weight :
55 kDa
Gene :
Tubb
Alternate Gene Name(s) :
TUBB
Uniprot ID :
P07437
Antibody Registry ID :
AB_2315513
Immunogen :
Recombinant protein
Immunogen Sequence :
* see additional information
Clonality :
Monoclonal
Myeloma Strain :
P3
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
2680681 31434579
Immunofluorescence Pubmed IDs :
24124604 25003205 17120293 26518186 27678524 28871032 25855186 26287727 27097159 27913291 31006649 31337818 25071420
Western Blot Pubmed IDs :
2680681 27090306 27143646 29753016 24966384 29247620 29232713 28798239 27687497 27686000 25473830 29176602 30391243 28798239 25302076 25473830 25302076 24523286 24124604 24098151 24098765 30573454 30867249 31328806
Pubmed IDs :
24278035 24124604 24098151 24098765 23818860 23525007 23509070 23250915 23342118 23209437 23152602 23128240 23110214 23029494 22937132 22848763 22842725 22848718 22573887 22635056 22482079 22427990 22026461 21949352 22145020 22057101 22037499 22084407 22043285 22025716 21828058 21333716 20696251 20599890 20720503 20530208 20357120 20335479 19822665 19946639 19540831 19862331 19771148 19546243 18586026 18463166 17880263 17535970 17174296 17194772 17060498 16887114 16899722 16537916 15802506 15520282 14636583 12529367 12417522 12234932 11948917 11734545 10969087 11051243 10996845 9628320 7889984 8223708 2680681 25070955
Additional Information :
E7 was originally generated by Drs. M. McCutcheon and S. Carroll from a mouse immunized with Drosophila fushi tarazu gene product. However, the antibody reacts specifically with beta-tubulin from a wide range of species (Chamydomonas to human).
DSHB Growth Medium :
RPMI
References (legacy) :
First Int'l. Symp. on Cytoskeleton & Dev. 8, 140-142.; Dev. Biol. 136, 104-117.; Eur. J. Cell Biol. 61, 54-66.; Eur. J. Cell Biol. 65, 14-25.; Eur. J. Cell Biol. 75, 344-352.; Clin. Cancer Res. 6, 3949-3956.; J. Cell. Biochem. 79, 542-556.; Human Mol. Genet. 20(24), 2803-2811.; J. Biol. Chem. 275(50), 39369-39378.; Hum. Mol. Genet. 11(24), 3007-3017.; Reprod. Toxicol. 5480, 1-15.; Genesis 32, 293-298.; J. Biol. Chem. 278(12), 10816-10823.; Mole. Cell 12, 1261-1274.; Genes Dev. 18, 2627-2638.; Mole. Cell. Biol. 26, 2736-2745.; J. Neurosci. 26(32), 8278-8288.; J. Biol. Chem. 282, 4458-7769.; Dev. Biol. 303(1), 214-221.; Dev. Biol. 335, 237-252.; J. Neurosci. 30(12), 4428-4439.; Nat. Cell Biol. 13(12), 1415-1423.; PLoS One 7(7):e42369. Doi:10.1371/journal.pone.0042369.; J. Cell Biol. 206(3), 367-376.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US