product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
neurofilaments, primary sensory and motor neurons
catalog :
E1.9
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
E1.9
application :
immunocytochemistry
more info or order :
citations: 4
| Reference |
|---|
Lawlor P, Marcotti W, Rivolta M, Kros C, Holley M. Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells. J Neurosci. 1999;19:9445-58 pubmed
|
Stainier D, Gilbert W. Pioneer neurons in the mouse trigeminal sensory system. Proc Natl Acad Sci U S A. 1990;87:923-7 pubmed
|
Stainier D, Gilbert W. Neuronal differentiation and maturation in the mouse trigeminal sensory system, in vivo and in vitro. J Comp Neurol. 1991;311:300-12 pubmed
|
product information
Internal ID :
3249
Name :
E1.9
Depositor Name :
Gilbert, W. / Stainier, D.
Depositor Institution :
Max Planck Institute for Heart & Lung Research
Date Deposited :
10/24/90
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
neurofilaments, primary sensory and motor neurons
Antigen Species :
Mouse
Host Species :
mouse
Isotype :
MIgM
Isotype for catalog (legacy) :
IgM
Positive Tested Species Reactivity :
Human,Mouse,Rat
Species Tested (legacy) :
mouse, rat
Initial Publication Pubmed ID :
2300585
Depositor Notes (Special Instructions) :
filaments in growing primary sensory and motor neurons
Collections :
Cytoskeleton,Human,Neurodevelopment
Search Keywords :
Gilbert, W. / Stainier, D., neurofilaments, primary sensory and motor neurons, Mouse, MIgM, Mouse/Rat/Human, , , AB_531876, monoclonal, Neurodevelopment/Cytoskeletal elements/Human, Immunofluorescence
Antibody Registry ID :
AB_531876
Immunogen :
Whole murine cells from the mid- and hindbrain (development stage: E12)
Immunogen Sequence :
Full length protein
Clonality :
Monoclonal
Myeloma Strain :
FOX-NY
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence
Immunofluorescence Pubmed IDs :
2300585 1753021 27569063
Pubmed IDs :
10531448
Additional Information :
In the original paper for E1.9 [PMID: 2300585], the immunogen was described as rat E12, but the subsequent paper from the same authors and in the Depositor's notes it was described as mouse E11. The E1.9 epitope is developmentally regulated. E1.9 recognizes a cytoplasmic epitope in the primary sensory and motor neurons during axonal outgrowth, appearing at E8.5 and disappearing by E12 in the mouse when the same cell populations become positive for mAb B10. It stains neural crest-derived sensory neurons (e.g., neurons of dorsal root ganglia) as well as placode-derived sensory neurons (e.g.neurons of cranial nerves VII and VIII). It is not clear which filaments are recognized by this antibody. For this reason we didn't link it to a Uniprot or gene ID. See mAb B10 for a related antibody.
DSHB Growth Medium :
RPMI
References (legacy) :
Proc. Nat'l Acad. Sci. USA 87, 923-927.
more info or order :
company information
Developmental Studies Hybridoma Bank