Draper | Developmental Studies Hybridoma Bank Draper 5D14 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Draper

catalog :

Draper 5D14

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Draper 5D14

reactivity :

fruit fly

application :

western blot, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 6

Reference
Purice M, Speese S, Logan M. Delayed glial clearance of degenerating axons in aged Drosophila is due to reduced PI3K/Draper activity. Nat Commun. 2016;7:12871 pubmed publisher
Meehan T, Serizier S, Kleinsorge S, McCall K. Analysis of Phagocytosis in the Drosophila Ovary. Methods Mol Biol. 2016;1457:79-95 pubmed publisher
Musashe D, Purice M, Speese S, Doherty J, Logan M. Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper. Cell Rep. 2016;16:1838-50 pubmed publisher
Timmons A, Mondragon A, Schenkel C, Yalonetskaya A, Taylor J, Moynihan K, et al. Phagocytosis genes nonautonomously promote developmental cell death in the Drosophila ovary. Proc Natl Acad Sci U S A. 2016;113:E1246-55 pubmed publisher
Meehan T, Kleinsorge S, Timmons A, Taylor J, McCall K. Polarization of the epithelial layer and apical localization of integrins are required for engulfment of apoptotic cells in the Drosophila ovary. Dis Model Mech. 2015;8:1603-14 pubmed publisher
Meehan T, Yalonetskaya A, Joudi T, McCall K. Detection of Cell Death and Phagocytosis in the Drosophila Ovary. Methods Mol Biol. 2015;1328:191-206 pubmed publisher

product information

Internal ID :

8339

Name :

Draper 5D14

Depositor Name :

Logan, M.

Depositor Institution :

Oregon Health and Science University

Date Deposited :

12/13/12

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Draper

Antigen Species :

Drosophila melanogaster

Host Species :

mouse

Isotype :

MIgG2a

Isotype for catalog (legacy) :

IgG2a

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

27498858

Depositor Notes (Special Instructions) :

Fixation: 4% PFA for whole mount.

Collections :

Drosophila antigens

Search Keywords :

Logan, M., Draper, Drosophila melanogaster , MIgG2a, Drosophila, drpr, CG2086, AB_2618105, monoclonal, Drosophila antigens, Immunofluorescence/Western Blot

Antigen Molecular Weight :

Predicted: Multiple isforms between 59 and 114 kDa

Gene :

drpr

Alternate Gene Name(s) :

CG2086

Uniprot ID :

Q9W0A0 Q9W0A1 M9PGU6 M9PDW5 M9PBI3 M9NEX8

Antibody Registry ID :

AB_2618105

Immunogen :

NPIVYNESLK

Immunogen Sequence :

Partial protein

Clonality :

Monoclonal

Myeloma Strain :

SP2/0

Epitope Mapped :

Yes

Epitope Location or Sequence :

NPIVYNESLK

Epitope Map PubMed ID :

27498858

Recommended Applications :

Immunofluorescence,Western Blot

Immunoblotting (legacy) :

yes

Immunofluorescence Pubmed IDs :

27647497 26324439 26884181 27557574 26398951 27498858

Western Blot Pubmed IDs :

27647497

Additional Information :

Draper is an engulfment receptor involved in cell death and phagocytosis. This antibody will recognize all Draper isoforms.

DSHB Growth Medium :

RPMI

more info or order :

Developmental Studies Hybridoma Bank product webpage