product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Dally-like protein (Dlp)
catalog :
Dally-like (13G8)
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Dally-like (13G8)
reactivity :
fruit fly
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 12
Reference
Neto M, Aguilar Hidalgo D, Casares F. Increased avidity for Dpp/BMP2 maintains the proliferation of progenitors-like cells in the Drosophila eye. Dev Biol. 2016;418:98-107 pubmed publisher
Yamazaki Y, Palmer L, Alexandre C, Kakugawa S, Beckett K, Gaugué I, et al. Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs. Nat Cell Biol. 2016;18:451-7 pubmed publisher
Dear M, Dani N, Parkinson W, Zhou S, Broadie K. Two classes of matrix metalloproteinases reciprocally regulate synaptogenesis. Development. 2016;143:75-87 pubmed publisher
Ferreira A, Milán M. Dally Proteoglycan Mediates the Autonomous and Nonautonomous Effects on Tissue Growth Caused by Activation of the PI3K and TOR Pathways. PLoS Biol. 2015;13:e1002239 pubmed publisher
Wang X, Page McCaw A. A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation. J Cell Biol. 2014;206:923-36 pubmed publisher
Friedman S, Dani N, Rushton E, Broadie K. Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila. Dis Model Mech. 2013;6:1400-13 pubmed publisher
Dani N, Nahm M, Lee S, Broadie K. A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling. PLoS Genet. 2012;8:e1003031 pubmed publisher
Ayers K, Mteirek R, Cervantes A, Lavenant Staccini L, Therond P, Gallet A. Dally and Notum regulate the switch between low and high level Hedgehog pathway signalling. Development. 2012;139:3168-79 pubmed publisher
Smart A, Course M, Rawson J, Selleck S, Van Vactor D, Johnson K. Heparan sulfate proteoglycan specificity during axon pathway formation in the Drosophila embryo. Dev Neurobiol. 2011;71:608-18 pubmed publisher
Szuperák M, Salah S, Meyer E, Nagarajan U, Ikmi A, Gibson M. Feedback regulation of Drosophila BMP signaling by the novel extracellular protein larval translucida. Development. 2011;138:715-24 pubmed publisher
Gallet A, Staccini Lavenant L, Therond P. Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis. Dev Cell. 2008;14:712-25 pubmed publisher
Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, et al. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science. 2003;299:2039-45 pubmed
product information
Internal ID :
725
Name :
Dally-like (13G8)
Depositor Name :
Beachy, P.A.
Depositor Institution :
Stanford University
Date Deposited :
10/21/03
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Dally-like protein (Dlp)
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
12663920
Collections :
Cell signaling,Drosophila antigens
Search Keywords :
Beachy, P.A., Dally-like protein (Dlp), Drosophila, MIgG1, Drosophila, dlp, CG32146, dly, Dally-like, AB_528191, monoclonal, Cell signaling/Drosophila antigens, Immunofluorescence/Western Blot/Immunoprecipitation/ELISA
Antigen Molecular Weight :
Predicted: 85 kDa
Gene :
dlp
Alternate Gene Name(s) :
CG32146, dly, Dally-like
Uniprot ID :
Q9VUG1
Antibody Registry ID :
AB_528191
Immunogen :
Recombinant Drosophila Dally-like protein (aa 523-702)/human IgG Fc domain fusion
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 523-702
Epitope Map PubMed ID :
12663920
Recommended Applications :
ELISA,Immunofluorescence,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunofluorescence Pubmed IDs :
12663920 21500363 18477454 22872085 27502436 26313758 25267296 24046358 23144627 26974662 26603384
Western Blot Pubmed IDs :
12663920 21266407
Immunoprecipitation Pubmed IDs :
12663920 21266407
ELISA Pubmed IDs :
12663920
Additional Information :
Recognizes an extracellular epitope. Dally-like protein (Dlp) is a cell surface protein member of the glypican family of heparan sulfate proteoglycans (HSPGs).
DSHB Growth Medium :
Iscove's
References (legacy) :
Science 299, 2039-2045.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US