product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Synapse-associated protein 47kD
catalog :
DSAP47-1 (nc46)
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DSAP47-1 (nc46)
reactivity :
fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 22
Reference
Andrés M, Seifert M, Spalthoff C, Warren B, Weiss L, Giraldo D, et al. Auditory Efferent System Modulates Mosquito Hearing. Curr Biol. 2016;26:2028-2036 pubmed publisher
Sadanandappa M, Blanco Redondo B, Michels B, Rodrigues V, Gerber B, Vijayraghavan K, et al. Synapsin function in GABA-ergic interneurons is required for short-term olfactory habituation. J Neurosci. 2013;33:16576-85 pubmed publisher
Zhao X, Pfuhl G, Surlykke A, Tro J, Berg B. A multisensory centrifugal neuron in the olfactory pathway of heliothine moths. J Comp Neurol. 2013;521:152-68 pubmed publisher
Halder P, Chen Y, Brauckhoff J, Hofbauer A, Dabauvalle M, Lewandrowski U, et al. Identification of Eps15 as antigen recognized by the monoclonal antibodies aa2 and ab52 of the Wuerzburg Hybridoma Library against Drosophila brain. PLoS ONE. 2011;6:e29352 pubmed publisher
Saumweber T, Weyhersmüller A, Hallermann S, Diegelmann S, Michels B, Bucher D, et al. Behavioral and synaptic plasticity are impaired upon lack of the synaptic protein SAP47. J Neurosci. 2011;31:3508-18 pubmed publisher
Nieratschker V, Schubert A, Jauch M, Bock N, Bucher D, Dippacher S, et al. Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila. PLoS Genet. 2009;5:e1000700 pubmed publisher
Fischer M, Raabe T, Heisenberg M, Sendtner M. Drosophila RSK negatively regulates bouton number at the neuromuscular junction. Dev Neurobiol. 2009;69:212-20 pubmed publisher
Hofbauer A, Ebel T, Waltenspiel B, Oswald P, Chen Y, Halder P, et al. The Wuerzburg hybridoma library against Drosophila brain. J Neurogenet. 2009;23:78-91 pubmed publisher
Schwenkert I, Eltrop R, Funk N, Steinert J, Schuster C, Scholz H. The hangover gene negatively regulates bouton addition at the Drosophila neuromuscular junction. Mech Dev. 2008;125:700-11 pubmed publisher
Menzel N, Schneeberger D, Raabe T. The Drosophila p21 activated kinase Mbt regulates the actin cytoskeleton and adherens junctions to control photoreceptor cell morphogenesis. Mech Dev. 2007;124:78-90 pubmed
Gögel S, Wakefield S, Tear G, Klämbt C, Gordon Weeks P. The Drosophila microtubule associated protein Futsch is phosphorylated by Shaggy/Zeste-white 3 at an homologous GSK3beta phosphorylation site in MAP1B. Mol Cell Neurosci. 2006;33:188-99 pubmed
Jauch E, Wecklein H, Stark F, Jauch M, Raabe T. The Drosophila melanogaster DmCK2beta transcription unit encodes for functionally non-redundant protein isoforms. Gene. 2006;374:142-52 pubmed
Porsch M, Sauer M, Schulze S, Bahlo A, Roth M, Pflugfelder G. The relative role of the T-domain and flanking sequences for developmental control and transcriptional regulation in protein chimeras of Drosophila OMB and ORG-1. Mech Dev. 2005;122:81-96 pubmed
Bogdan S, Grewe O, Strunk M, Mertens A, Klämbt C. Sra-1 interacts with Kette and Wasp and is required for neuronal and bristle development in Drosophila. Development. 2004;131:3981-9 pubmed
Godenschwege T, Reisch D, Diegelmann S, Eberle K, Funk N, Heisenberg M, et al. Flies lacking all synapsins are unexpectedly healthy but are impaired in complex behaviour. Eur J Neurosci. 2004;20:611-22 pubmed
Funk N, Becker S, Huber S, Brunner M, Buchner E. Targeted mutagenesis of the Sap47 gene of Drosophila: flies lacking the synapse associated protein of 47 kDa are viable and fertile. BMC Neurosci. 2004;5:16 pubmed
Arnold C, Reisch N, Leibold C, Becker S, Prüfert K, Sautter K, et al. Structure-function analysis of the cysteine string protein in Drosophila: cysteine string, linker and C terminus. J Exp Biol. 2004;207:1323-34 pubmed
Just S, Gronenberg W. The control of mandible movements in the ant Odontomachus. J Insect Physiol. 1999;45:231-240 pubmed
Muller D, Abel R, Brandt R, Zöckler M, Menzel R. Differential parallel processing of olfactory information in the honeybee, Apis mellifera L. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2002;188:359-70 pubmed
Siegmund T, Korge G. Innervation of the ring gland of Drosophila melanogaster. J Comp Neurol. 2001;431:481-91 pubmed
Hummel T, Krukkert K, Roos J, Davis G, Klämbt C. Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron. 2000;26:357-70 pubmed
Reichmuth C, Becker S, Benz M, Debel K, Reisch D, Heimbeck G, et al. The sap47 gene of Drosophila melanogaster codes for a novel conserved neuronal protein associated with synaptic terminals. Brain Res Mol Brain Res. 1995;32:45-54 pubmed
product information
Internal ID :
7292
Name :
DSAP47-1 (nc46)
Depositor Name :
Buchner, E. / Hofbauer, A.
Depositor Institution :
University of Wuerzburg - Germany
Depositor Website :
http://www.neurobiologie.ukw.de/en/staff/prof-dr-erich-buchner.html
Date Deposited :
2/5/11
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Synapse-associated protein 47kD
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Ant,Drosophila,Fish,Insects,Mosquito
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
7494462
Depositor Notes (Special Instructions) :
The antibody nc46 recognizes 9 SAP47 isoforms (see PMID: 15117418).
Collections :
Drosophila antigens,Extracellular matrix proteins,Neurodevelopment
Search Keywords :
Buchner, E. / Hofbauer, A., Synapse-associated protein 47kD, Drosophila , MIgG1, kappa light chain, Drosophila/Insects/Mosquito/Fish/Ant, Sap47 , Dmel_CG8884, AB_2617213, Monoclonal, Drosophila antigens/Extracellular matrix proteins/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Western blot
Antigen Molecular Weight :
47 kDa
Gene :
Sap47
Alternate Gene Name(s) :
Dmel_CG8884
Uniprot ID :
A0A0B4LH71
Antibody Registry ID :
AB_2617213
Immunogen :
Brain homogenate
Immunogen Sequence :
Full length protein
Clonality :
Monoclonal
Myeloma Strain :
P3X.63-Ag8.653
Epitope Mapped :
Yes
Epitope Location or Sequence :
N-terminal decapeptide FSGLTNQFTS
Epitope Map PubMed ID :
19132598
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
7494462 15117418 19132598 10839355 21368063 15269173 12770370 15255973
Immunofluorescence Pubmed IDs :
7494462 11223816 21368063 15269173 16949836 19160443 18524547 27476597 22684993 22684993 12073081
Western Blot Pubmed IDs :
15117418 21368063 15010483 16530986 17097274 22206011 19851455 15582779 24133261 15582779
Additional Information :
RRID:AB_2617213. FBgn0013334.
DSHB Growth Medium :
RPMI
References (legacy) :
Mol. Brain Res. 32(1), 45-54.; BMC Neurosci. 5:16.; J. Neurogenet. 23(1-2), 78-91.; J. Neurosci. 31(9), 3508-3518.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US