integrin alphaPS1 (multiple edematous wing) | Developmental Studies Hybridoma Bank DK.1A4 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

integrin alphaPS1 (multiple edematous wing)

catalog :

DK.1A4

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DK.1A4

reactivity :

fruit fly

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 13

Reference
Park S, Lee C, Lee J, Park J, Roshandell M, Brennan C, et al. Requirement for and polarized localization of integrin proteins during Drosophila wound closure. Mol Biol Cell. 2018;29:2137-2147 pubmed publisher
Kim M, Shrestha B, Blazeski R, Mason C, Grueber W. Integrins establish dendrite-substrate relationships that promote dendritic self-avoidance and patterning in drosophila sensory neurons. Neuron. 2012;73:79-91 pubmed publisher
Egoz Matia N, Nachman A, Halachmi N, Toder M, Klein Y, Salzberg A. Spatial regulation of cell adhesion in the Drosophila wing is mediated by Delilah, a potent activator of βPS integrin expression. Dev Biol. 2011;351:99-109 pubmed publisher
Delon I, Brown N. The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium. J Cell Sci. 2009;122:4363-74 pubmed publisher
Dinkins M, Fratto V, LeMosy E. Integrin alpha chains exhibit distinct temporal and spatial localization patterns in epithelial cells of the Drosophila ovary. Dev Dyn. 2008;237:3927-39 pubmed publisher
Araujo H, Negreiros E, Bier E. Integrins modulate Sog activity in the Drosophila wing. Development. 2003;130:3851-64 pubmed
Baker S, Lorenzen J, Miller S, Bunch T, Jannuzi A, Ginsberg M, et al. Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7. Genetics. 2002;162:285-96 pubmed
Hoang B, Chiba A. Genetic analysis on the role of integrin during axon guidance in Drosophila. J Neurosci. 1998;18:7847-55 pubmed
Blair S, Brower D, Thomas J, Zavortink M. The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila. Development. 1994;120:1805-15 pubmed
Gullberg D, Fessler L, Fessler J. Differentiation, extracellular matrix synthesis, and integrin assembly by Drosophila embryo cells cultured on vitronectin and laminin substrates. Dev Dyn. 1994;199:116-28 pubmed
Wilcox M, Brower D, Smith R. A position-specific cell surface antigen in the drosophila wing imaginal disc. Cell. 1981;25:159-64 pubmed
Brower D, Wilcox M, Piovant M, Smith R, Reger L. Related cell-surface antigens expressed with positional specificity in Drosophila imaginal discs. Proc Natl Acad Sci U S A. 1984;81:7485-9 pubmed
Brower D, Piovant M, Reger L. Developmental analysis of Drosophila position-specific antigens. Dev Biol. 1985;108:120-30 pubmed

product information

Internal ID :

1382

Name :

DK.1A4

Depositor Name :

Brower, D.

Depositor Institution :

Harvard Medical School

Date Deposited :

7/17/02

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

integrin alphaPS1 (multiple edematous wing)

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG1, kappa light chain

Isotype for catalog (legacy) :

IgG1, kappa light chain

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

6791831

Depositor Notes (Special Instructions) :

This antibody doesn't work for immunoblotting and is aldehyde sensitive.

Collections :

Cell adhesion,Cell signaling,Drosophila antigens,Neurodevelopment,Skeletal muscle

Search Keywords :

Brower, D., integrin alphaPS1 (multiple edematous wing), Drosophila, MIgG1, kappa light chain, Drosophila, mew, alphaPS1, CG1771, AB_528303, Monoclonal, Cell adhesion/Cell signaling/Drosophila antigens/Skeletal muscle/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Immunoprecipitation

Antigen Molecular Weight :

Multiple isoforms

Gene :

mew

Alternate Gene Name(s) :

alphaPS1, CG1771

Uniprot ID :

Q24247

Antibody Registry ID :

AB_528303

Synonyms (Alternate Clone Names) :

PS1, alphaPS1

Immunogen :

Sonicated imaginal discs

Immunogen Sequence :

Total protein

Clonality :

Monoclonal

Myeloma Strain :

P3/NSI

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry,Immunoprecipitation

Immunoblotting (legacy) :

Immunohistochemistry Pubmed IDs :

9742153

Immunofluorescence Pubmed IDs :

6791831 6390440 19903692 21215259 12835400 7924988 19035354 22243748 12242240 3918898

Immunoprecipitation Pubmed IDs :

7515725 12835400

Additional Information :

Integrins are heterodimers of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain (resulting from the cleavage of the mew gene product for alphaPS1) linked by a disulfide bond. AlphaPS1 associates with betaPS.

DSHB Growth Medium :

RPMI

References (legacy) :

Proc. Natl. Acad. Sci. 81, 7485-7489.

more info or order :

Developmental Studies Hybridoma Bank product webpage