product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
catenin, alpha- (Drosophila)
catalog :
DCAT-1
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
DCAT-1
reactivity :
fruit fly
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 16
Reference
Houssin E, Tepass U, Laprise P. Girdin-mediated interactions between cadherin and the actin cytoskeleton are required for epithelial morphogenesis in Drosophila. Development. 2015;142:1777-84 pubmed publisher
Zhang Y, Kong D, Reichl L, Vogt N, Wolf F, Großhans J. The glucosyltransferase Xiantuan of the endoplasmic reticulum specifically affects E-Cadherin expression and is required for gastrulation movements in Drosophila. Dev Biol. 2014;390:208-20 pubmed publisher
Harumoto T, Anbutsu H, Fukatsu T. Male-killing Spiroplasma induces sex-specific cell death via host apoptotic pathway. PLoS Pathog. 2014;10:e1003956 pubmed publisher
Toret C, D Ambrosio M, Vale R, Simon M, Nelson W. A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell-cell adhesion. J Cell Biol. 2014;204:265-79 pubmed publisher
Bulgakova N, Grigoriev I, Yap A, Akhmanova A, Brown N. Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries. J Cell Biol. 2013;201:887-901 pubmed publisher
Wang Y, Khan Z, Wieschaus E. Distinct Rap1 activity states control the extent of epithelial invagination via ?-catenin. Dev Cell. 2013;25:299-309 pubmed publisher
Chu D, Pan H, Wan P, Wu J, Luo J, Zhu H, et al. AIP1 acts with cofilin to control actin dynamics during epithelial morphogenesis. Development. 2012;139:3561-71 pubmed publisher
Sarpal R, Pellikka M, Patel R, Hui F, Godt D, Tepass U. Mutational analysis supports a core role for Drosophila α-catenin in adherens junction function. J Cell Sci. 2012;125:233-45 pubmed publisher
Bhogal B, Jepson J, Savva Y, Pepper A, Reenan R, Jongens T. Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein. Nat Neurosci. 2011;14:1517-24 pubmed publisher
Peterson Nedry W, Erdeniz N, Kremer S, Yu J, Baig Lewis S, Wehrli M. Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo. Dev Biol. 2008;320:226-41 pubmed publisher
Oda H, Tsukita S. Dynamic features of adherens junctions during Drosophila embryonic epithelial morphogenesis revealed by a Dalpha-catenin-GFP fusion protein. Dev Genes Evol. 1999;209:218-25 pubmed
Takahashi K, Matsuo T, Katsube T, Ueda R, Yamamoto D. Direct binding between two PDZ domain proteins Canoe and ZO-1 and their roles in regulation of the jun N-terminal kinase pathway in Drosophila morphogenesis. Mech Dev. 1998;78:97-111 pubmed
Oda H, Uemura T, Takeichi M. Phenotypic analysis of null mutants for DE-cadherin and Armadillo in Drosophila ovaries reveals distinct aspects of their functions in cell adhesion and cytoskeletal organization. Genes Cells. 1997;2:29-40 pubmed
Tepass U. Crumbs, a component of the apical membrane, is required for zonula adherens formation in primary epithelia of Drosophila. Dev Biol. 1996;177:217-25 pubmed
Oda H, Uemura T, Shiomi K, Nagafuchi A, Tsukita S, Takeichi M. Identification of a Drosophila homologue of alpha-catenin and its association with the armadillo protein. J Cell Biol. 1993;121:1133-40 pubmed
Oda H, Uemura T, Harada Y, Iwai Y, Takeichi M. A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion. Dev Biol. 1994;165:716-26 pubmed
product information
Internal ID :
497
Name :
DCAT-1
Depositor Name :
Takeichi, M.
Depositor Institution :
RIKEN Center for Developmental Biology
Date Deposited :
12/7/05
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
catenin, alpha- (Drosophila)
Antigen Species :
Drosophila
Host Species :
rat
Isotype :
RIgG2a, kappa light chain
Isotype for catalog (legacy) :
IgG2a, kappa light chain
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
8501118
Collections :
Cell adhesion,Cell signaling,Cytoskeleton,Drosophila antigens
Search Keywords :
Takeichi, M., catenin, alpha- (Drosophila), Drosophila, RIgG2a, kappa light chain, Drosophila, alpha-Cat, CG17947, ?cat, D?-cat, a-cat, ?-catenin, AB_532377, monoclonal, Cell signaling/Cytoskeletal elements/Drosophila antigens/cell adhesion, Immunofluorescence/Western Blot/Immunoprecipitation
Antigen Molecular Weight :
Predicted: 102 kDa; Apparent: 110 kDa
Gene :
alpha-Cat
Alternate Gene Name(s) :
CG17947, ?cat, D?-cat, a-cat, ?-catenin
Uniprot ID :
P35220
Antibody Registry ID :
AB_532377
Immunogen :
Recombinant Drosophila alpha-catenin fused with the T7 phage gene 10 protein.
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
P3U1
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 240-910
Epitope Map PubMed ID :
8501118
Recommended Applications :
Immunofluorescence,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunofluorescence Pubmed IDs :
8501118 10079365 7958432 8660889 22266901 9858699 9112438 24550732 18561909 22899846 24681004 25968313 22037499
Western Blot Pubmed IDs :
8501118 10079365 7958432 22266901 23623612 18561909 24446484 24681004 25968313 22037499 23751496
Immunoprecipitation Pubmed IDs :
8501118 7958432
DSHB Growth Medium :
Iscove's
References (legacy) :
J. Cell Biol. 121, 1133-1140.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US