Metastasin 100 calcium-binding protein A4 (Calvasculin) | Developmental Studies Hybridoma Bank CPTC-S100A4-3 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Metastasin 100 calcium-binding protein A4 (Calvasculin)

catalog :

CPTC-S100A4-3

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CPTC-S100A4-3

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 2

Reference
Orre L, Panizza E, Kaminskyy V, Vernet E, Gräslund T, Zhivotovsky B, et al. S100A4 interacts with p53 in the nucleus and promotes p53 degradation. Oncogene. 2013;32:5531-40 pubmed publisher
Dong H, Ding H, Young K, Blaivas M, Christensen P, Wang M. Advanced intimal hyperplasia without luminal narrowing of leptomeningeal arteries in CADASIL. Stroke. 2013;44:1456-8 pubmed publisher

product information

Internal ID :

6173

Name :

CPTC-S100A4-3

Depositor Name :

Clinical Proteomics Technologies for Cancer

Depositor Institution :

National Cancer Institute

Depositor Website :

http://proteomics.cancer.gov

Date Deposited :

10/21/08

Allow Hybridoma Distribution :

Cells Available (legacy) :

Antigen :

Metastasin 100 calcium-binding protein A4 (Calvasculin)

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG2c

Isotype for catalog (legacy) :

IgG2a, kappa light chain

Positive Tested Species Reactivity :

Human

Initial Publication Pubmed ID :

23482599

Depositor Notes (Special Instructions) :

This antibody has been validated by the Human Protein Atlas.

Collections :

Cancer targets - NCI,Human

Search Keywords :

S100A4; 18A2; 42A; CAPL; Calvasculin; FSP1; MTS1; Metastasin; OTTHUMP00000015467; OTTHUMP00000015468; OTTHUMP00000015469; OTTHUMP00000032895; P9KA; PEL98

Antigen Molecular Weight :

12 kDa

Gene :

S100A4

Alternate Gene Name(s) :

S100A4; 18A2; 42A; CAPL; Calvasculin; FSP1; MTS1; Metastasin; P9KA; PEL98

Uniprot ID :

P26447

Antibody Registry ID :

AB_1553803

Immunogen :

Recombinant Full Length Protein

Clonality :

Monoclonal

Myeloma Strain :

P3x63Ag8.653

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

yes

Immunohistochemistry Pubmed IDs :

23482599

Immunofluorescence Pubmed IDs :

23752197

Western Blot Pubmed IDs :

23752197

Immunoprecipitation Pubmed IDs :

23752197

Additional Information :

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in motility, invasion, and tubulin polymerization. RRID:AB_1553803

Additional Characterization :

https://antibodies.cancer.gov/detail/CPTC-S100A4-3

Human Protein Atlas :

https://www.proteinatlas.org/ENSG00000196154-S100A4/antibody54/antibody

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage