Aldo-keto Reductase Family 1 Member B1 | Developmental Studies Hybridoma Bank CPTC-AKR1B1-1 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Aldo-keto Reductase Family 1 Member B1

catalog :

CPTC-AKR1B1-1

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CPTC-AKR1B1-1

reactivity :

human

application :

western blot, ELISA

more info or order :

Developmental Studies Hybridoma Bank product webpage

product information

Internal ID :

5541

Name :

CPTC-AKR1B1-1

Depositor Name :

Clinical Proteomics Technologies for Cancer

Depositor Institution :

National Cancer Institute

Depositor Website :

http://proteomics.cancer.gov

Date Deposited :

10/21/08

Allow Hybridoma Distribution :

Cells Available (legacy) :

Antigen :

Aldo-keto Reductase Family 1 Member B1

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1, kappa light chain

Positive Tested Species Reactivity :

Human

Collections :

Cancer targets - NCI,Human

Search Keywords :

CPTC, Aldo-keto Reductase Family 1 Member B1, AKR1B1; ADR; ALDR1; ALR2; AR; EC 1.1.1.21; MGC1804, monoclonal, AB_2273742, IgG1, human, ELISA,FFPE,Microarray,Western Blot

Antigen Molecular Weight :

36.1 kDa

Gene :

AKR1B1

Alternate Gene Name(s) :

AKR1B1; ADR; ALDR1; ALR2; AR; EC 1.1.1.21; MGC1804

Uniprot ID :

P15121

Antibody Registry ID :

AB_2273742

Immunogen :

Recombinant Full Length Protein

Immunogen Sequence :

Full-length

Clonality :

Monoclonal

Myeloma Strain :

P3x63Ag8.653

Epitope Mapped :

Recommended Applications :

ELISA,FFPE,Microarray,Western Blot

Immunoblotting (legacy) :

yes

Depositor Growth Medium :

20% fetal calf serum in Iscove's Modified DMEM with 1x pen/strep

Additional Information :

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabeticcomplications by catalyzing the reduction of glucose to sorbitol. There are a few putativepseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3.It functions to catalyze the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

Additional Characterization :

https://antibodies.cancer.gov/detail/CPTC-AKR1B1-1

Human Protein Atlas :

https://www.proteinatlas.org/ENSG00000085662-AKR1B1/antibody

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage