integrin alphaPS2 (inflated) | Developmental Studies Hybridoma Bank CF.2C7 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

integrin alphaPS2 (inflated)

catalog :

CF.2C7

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

CF.2C7

reactivity :

fruit fly

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 16

Reference
Park S, Lee C, Lee J, Park J, Roshandell M, Brennan C, et al. Requirement for and polarized localization of integrin proteins during Drosophila wound closure. Mol Biol Cell. 2018;29:2137-2147 pubmed publisher
Wang Z, Rabouille C, Geisbrecht E. Loss of a Clueless-dGRASP complex results in ER stress and blocks Integrin exit from the perinuclear endoplasmic reticulum in Drosophila larval muscle. Biol Open. 2015;4:636-48 pubmed publisher
Lewellyn L, Cetera M, Horne Badovinac S. Misshapen decreases integrin levels to promote epithelial motility and planar polarity in Drosophila. J Cell Biol. 2013;200:721-9 pubmed publisher
Kim M, Shrestha B, Blazeski R, Mason C, Grueber W. Integrins establish dendrite-substrate relationships that promote dendritic self-avoidance and patterning in drosophila sensory neurons. Neuron. 2012;73:79-91 pubmed publisher
Egoz Matia N, Nachman A, Halachmi N, Toder M, Klein Y, Salzberg A. Spatial regulation of cell adhesion in the Drosophila wing is mediated by Delilah, a potent activator of βPS integrin expression. Dev Biol. 2011;351:99-109 pubmed publisher
Dinkins M, Fratto V, LeMosy E. Integrin alpha chains exhibit distinct temporal and spatial localization patterns in epithelial cells of the Drosophila ovary. Dev Dyn. 2008;237:3927-39 pubmed publisher
Helsten T, Bunch T, Kato H, Yamanouchi J, Choi S, Jannuzi A, et al. Differences in regulation of Drosophila and vertebrate integrin affinity by talin. Mol Biol Cell. 2008;19:3589-98 pubmed publisher
Devenport D, Bunch T, Bloor J, Brower D, Brown N. Mutations in the Drosophila alphaPS2 integrin subunit uncover new features of adhesion site assembly. Dev Biol. 2007;308:294-308 pubmed
Araujo H, Negreiros E, Bier E. Integrins modulate Sog activity in the Drosophila wing. Development. 2003;130:3851-64 pubmed
Baker S, Lorenzen J, Miller S, Bunch T, Jannuzi A, Ginsberg M, et al. Genetic interaction between integrins and moleskin, a gene encoding a Drosophila homolog of importin-7. Genetics. 2002;162:285-96 pubmed
Hoang B, Chiba A. Genetic analysis on the role of integrin during axon guidance in Drosophila. J Neurosci. 1998;18:7847-55 pubmed
Graner M, Bunch T, Baumgartner S, Kerschen A, Brower D. Splice variants of the Drosophila PS2 integrins differentially interact with RGD-containing fragments of the extracellular proteins tiggrin, ten-m, and D-laminin 2. J Biol Chem. 1998;273:18235-41 pubmed
Blair S, Brower D, Thomas J, Zavortink M. The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila. Development. 1994;120:1805-15 pubmed
Gullberg D, Fessler L, Fessler J. Differentiation, extracellular matrix synthesis, and integrin assembly by Drosophila embryo cells cultured on vitronectin and laminin substrates. Dev Dyn. 1994;199:116-28 pubmed
Brower D, Wilcox M, Piovant M, Smith R, Reger L. Related cell-surface antigens expressed with positional specificity in Drosophila imaginal discs. Proc Natl Acad Sci U S A. 1984;81:7485-9 pubmed
Brower D, Piovant M, Reger L. Developmental analysis of Drosophila position-specific antigens. Dev Biol. 1985;108:120-30 pubmed

product information

Internal ID :

1370

Name :

CF.2C7

Depositor Name :

Brower, D.

Depositor Institution :

Harvard Medical School

Date Deposited :

7/17/02

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

integrin alphaPS2 (inflated)

Antigen Species :

Drosophila

Host Species :

mouse

Isotype :

MIgG1, kappa light chain

Isotype for catalog (legacy) :

IgG1, kappa light chain

Positive Tested Species Reactivity :

Drosophila

Species Tested (legacy) :

Drosophila

Initial Publication Pubmed ID :

6390440

Depositor Notes (Special Instructions) :

This antibody doesn't work for immunoblotting and is aldehyde sensitive.

Collections :

Cell adhesion,Cell signaling,Drosophila antigens,Neurodevelopment,Skeletal muscle

Search Keywords :

Brower, D., integrin alphaPS2 (inflated), Drosophila, MIgG1, kappa light chain , Drosophila, if, alphaPS2, CG9623, AB_528304, Monoclonal, Cell adhesion/Cell signaling/Drosophila antigens/Skeletal muscle/Neurodevelopment, Immunohistochemistry/Immunofluorescence/Immunoprecipitation/FACS

Antigen Molecular Weight :

Multiple isoforms

Gene :

Alternate Gene Name(s) :

alphaPS2, CG9623

Uniprot ID :

P12080

Antibody Registry ID :

AB_528304

Synonyms (Alternate Clone Names) :

PS2, alphaPS2

Immunogen :

Sonicated imaginal discs

Immunogen Sequence :

Total protein

Clonality :

Monoclonal

Myeloma Strain :

P3/NSI

Epitope Mapped :

Recommended Applications :

FACS,Immunofluorescence,Immunohistochemistry,Immunoprecipitation

Immunoblotting (legacy) :

Immunohistochemistry Pubmed IDs :

9742153

Immunofluorescence Pubmed IDs :

6390440 21215259 25862246 23509067 7924988 19035354 22243748 17618618 12242240 3918898

Immunoprecipitation Pubmed IDs :

7515725 12835400

FACS Pubmed IDs :

18508915 9660786 17618618

Additional Information :

Integrins are heterodimers of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain (resulting from the cleavage of the if gene product for alphaPS2) linked by a disulfide bond. AlphaPS2 associates with betaPS.

DSHB Growth Medium :

RPMI

References (legacy) :

Proc. Natl. Acad. Sci. 81, 7485-7489.

more info or order :

Developmental Studies Hybridoma Bank product webpage