leukocyte secretory granules, chicken | Developmental Studies Hybridoma Bank ANTI-GRL(1) product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

leukocyte secretory granules, chicken

catalog :

ANTI-GRL(1)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ANTI-GRL(1)

reactivity :

human, chicken

application :

immunocytochemistry, immunoprecipitation, FACS

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 3

Reference
Bódi I, Nagy N, Sinka L, Igyártó B, Oláh I. Novel monoclonal antibodies recognise guinea fowl thrombocytes. Acta Vet Hung. 2009;57:239-46 pubmed publisher
Thomas J, Pourquie O, Coltey M, Vaigot P, Le Douarin N. Identification in the chicken of GRL1 and GRL2: two granule proteins expressed on the surface of activated leukocytes. Exp Cell Res. 1993;204:156-66 pubmed
Thomas J, Stieber A, Gonatas N. Two proteins associated with secretory granule membranes identified in chicken regulated secretory cells. J Cell Sci. 1994;107 ( Pt 5):1297-308 pubmed

product information

Internal ID :

773

Name :

ANTI-GRL(1)

Depositor Name :

Thomas, J.-L.

Depositor Institution :

INSERM U495, Hopital de la Salpetriere

Date Deposited :

10/20/92

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

leukocyte secretory granules, chicken

Antigen Species :

Chicken

Host Species :

mouse

Isotype :

MIgG3

Isotype for catalog (legacy) :

IgG3

Positive Tested Species Reactivity :

Chicken

Species Tested (legacy) :

chicken

Initial Publication Pubmed ID :

8484827

Depositor Notes (Special Instructions) :

Recognizes granulocytes, activated thrombocytes, acinar cells of the pancreas, and is a marker of secretory granules expressed on the plasma membrane of activated cells.

Collections :

Cell markers,Cell signaling

Search Keywords :

Thomas, J.-L., leukocyte secretory granules, chicken, Chicken, MIgG3, Chicken, , , AB_10129757, monoclonal, Cell markers/Cell signaling, Immunofluorescence/Immunoprecipitation/FACS

Antigen Molecular Weight :

Apparent: 92 kDa

Antibody Registry ID :

AB_10129757

Synonyms (Alternate Clone Names) :

I-A5

Immunogen :

E15 bursa of Fabricius

Immunogen Sequence :

Full length protein

Clonality :

Monoclonal

Myeloma Strain :

SP2/0

Epitope Mapped :

Yes

Epitope Location or Sequence :

Cell surface epitope

Epitope Map PubMed ID :

8484827

Recommended Applications :

FACS,Immunofluorescence,Immunoprecipitation

Immunofluorescence Pubmed IDs :

8484827 7929636

Immunoprecipitation Pubmed IDs :

8484827 7929636

FACS Pubmed IDs :

8484827

Pubmed IDs :

19584037

Additional Information :

Stains intracytoplasmic granules of granulocytes and thrombocytes and are present on the surface of these cells as a result of exocytosis of the intracytoplasmic granules. GRL1 is a protein shed or dsecreted by well-differenciated granulocytes and probably directly linked to membrane phospholipids.

DSHB Growth Medium :

Iscove's

References (legacy) :

Exp. Cell Res. 204, 156-166.; Acta Vet. Hung. 57(2), 239-246.

more info or order :

Developmental Studies Hybridoma Bank product webpage