| Published Application/Species/Sample/Dilution | Reference |
|---|
- blocking or activating experiments; human; fig 7
| Barrow McGee R, Kishi N, Joffre C, Ménard L, Hervieu A, Bakhouche B, et al. Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes. Nat Commun. 2016;7:11942 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:50
- immunocytochemistry; human; 1:50
| Priglinger C, Szober C, Priglinger S, Merl J, Euler K, Kernt M, et al. Galectin-3 induces clustering of CD147 and integrin-?1 transmembrane glycoprotein receptors on the RPE cell surface. PLoS ONE. 2013;8:e70011 pubmed publisher |
| Conway J, Isomursu A, Follain G, H xe4 rm xe4 V, Jou Oll xe9 E, Pasquier N, et al. Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling. Proc Natl Acad Sci U S A. 2023;120:e2304288120 pubmed publisher |
| Huber M, Casares Arias J, F xe4 ssler R, M xfc ller D, Strohmeyer N. In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells. Nat Commun. 2023;14:2143 pubmed publisher |
| Rom xe1 n Fern xe1 ndez A, Mansour M, Kugeratski F, Anand J, Sandilands E, Galbraith L, et al. Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Sci Adv. 2023;9:eabq1858 pubmed publisher |
| Katsuno Kambe H, Teo J, Ju R, Hudson J, Stehbens S, Yap A. Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation. elife. 2021;10: pubmed publisher |
| Howe E, Burnette M, Justice M, Schnepp P, Hedrick V, Clancy J, et al. Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth. Nat Commun. 2020;11:3017 pubmed publisher |
| Ethaeb A, Mohammad M, Madkhali Y, Featherby S, Maraveyas A, Greenman J, et al. Accumulation of tissue factor in endothelial cells promotes cellular apoptosis through over-activation of Src1 and involves β1-integrin signalling. Apoptosis. 2020;25:29-41 pubmed publisher |
| Wang M, Nagle R, Knudsen B, Cress A, Rogers G. Centrosome loss results in an unstable genome and malignant prostate tumors. Oncogene. 2019;: pubmed publisher |
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| Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti Bugaeva O, Paatero I, et al. Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. elife. 2018;7: pubmed publisher |
| Spiess M, Hernández Varas P, Oddone A, Olofsson H, Blom H, Waithe D, et al. Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions. J Cell Biol. 2018;217:1929-1940 pubmed publisher |
| Sedgwick A, Olivia Balmert M, D SOUZA SCHOREY C. The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux. Exp Cell Res. 2018;365:194-207 pubmed publisher |
| Eckert M, Santiago Medina M, Lwin T, Kim J, Courtneidge S, Yang J. ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions. J Cell Sci. 2017;130:2036-2048 pubmed publisher |
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| Chen Z, Givens C, Reader J, Tzima E. Haemodynamics Regulate Fibronectin Assembly via PECAM. Sci Rep. 2017;7:41223 pubmed publisher |
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| Lu L, Lin C, Yan Z, Wang S, Zhang Y, Wang S, et al. Kindlin-3 Is Essential for the Resting ?4?1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions. J Biol Chem. 2016;291:10363-71 pubmed publisher |
| Petridou N, Skourides P. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016;7:10899 pubmed publisher |
| Wang C, de Jong E, Sjollema K, Zuhorn I. Entry of PIP3-containing polyplexes into MDCK epithelial cells by local apical-basal polarity reversal. Sci Rep. 2016;6:21436 pubmed publisher |
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| Leyme A, Marivin A, Perez Gutierrez L, Nguyen L, Garcia Marcos M. Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin. J Cell Biol. 2015;210:1165-84 pubmed publisher |
| Clancy J, Sedgwick A, Rosse C, Muralidharan Chari V, Raposo G, Method M, et al. Regulated delivery of molecular cargo to invasive tumour-derived microvesicles. Nat Commun. 2015;6:6919 pubmed publisher |
| Ishihara S, Yasuda M, Ishizu A, Ishikawa M, Shirato H, Haga H. Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells. Oncotarget. 2015;6:4602-14 pubmed |
| Dey Guha I, Alves C, Yeh A, Salony -, Sole X, Darp R, et al. A mechanism for asymmetric cell division resulting in proliferative asynchronicity. Mol Cancer Res. 2015;13:223-30 pubmed publisher |
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| Gershlak J, Black L. Beta 1 integrin binding plays a role in the constant traction force generation in response to varying stiffness for cells grown on mature cardiac extracellular matrix. Exp Cell Res. 2015;330:311-24 pubmed publisher |
| Fiore V, Ju L, Chen Y, Zhu C, Barker T. Dynamic catch of a Thy-1-α5β1+syndecan-4 trimolecular complex. Nat Commun. 2014;5:4886 pubmed publisher |
| Ishida S, Tanaka R, Yamaguchi N, Ogata G, Mizutani T, Kawabata K, et al. Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel. PLoS ONE. 2014;9:e99655 pubmed publisher |
| Mai A, Muharram G, Barrow McGee R, Baghirov H, Rantala J, Kermorgant S, et al. Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1. J Cell Sci. 2014;127:1938-52 pubmed publisher |
| Landowski T, Gard J, Pond E, Pond G, Nagle R, Geffre C, et al. Targeting integrin α6 stimulates curative-type bone metastasis lesions in a xenograft model. Mol Cancer Ther. 2014;13:1558-66 pubmed publisher |
| Flannagan R, Canton J, Furuya W, Glogauer M, Grinstein S. The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell. 2014;25:1511-22 pubmed publisher |
| Zwolanek D, Veit G, Eble J, Gullberg D, Ruggiero F, Heino J, et al. Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER. Biochem J. 2014;459:217-27 pubmed publisher |
| Mhanna R, Kashyap A, Palazzolo G, Vallmajo Martin Q, Becher J, Moller S, et al. Chondrocyte culture in three dimensional alginate sulfate hydrogels promotes proliferation while maintaining expression of chondrogenic markers. Tissue Eng Part A. 2014;20:1454-64 pubmed publisher |
| Lázaro Diéguez F, Cohen D, Fernandez D, Hodgson L, Van IJzendoorn S, Müsch A. Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes. J Cell Biol. 2013;203:251-64 pubmed publisher |
| Ishihara S, Yasuda M, Harada I, Mizutani T, Kawabata K, Haga H. Substrate stiffness regulates temporary NF-κB activation via actomyosin contractions. Exp Cell Res. 2013;319:2916-27 pubmed publisher |
| LaRusch G, Merkulova A, Mahdi F, Shariat Madar Z, Sitrin R, Cines D, et al. Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through ?1-integrin and VEGFR2. Am J Physiol Heart Circ Physiol. 2013;305:H305-20 pubmed publisher |
| Schaffner F, Yokota N, Carneiro Lobo T, Kitano M, Schaffer M, Anderson G, et al. Endothelial protein C receptor function in murine and human breast cancer development. PLoS ONE. 2013;8:e61071 pubmed publisher |
| Zawistowski J, Nakamura K, Parker J, Granger D, Golitz B, Johnson G. MicroRNA 9-3p targets ?1 integrin to sensitize claudin-low breast cancer cells to MEK inhibition. Mol Cell Biol. 2013;33:2260-74 pubmed publisher |
| Hayase J, Kamakura S, Iwakiri Y, Yamaguchi Y, Izaki T, Ito T, et al. The WD40 protein Morg1 facilitates Par6-aPKC binding to Crb3 for apical identity in epithelial cells. J Cell Biol. 2013;200:635-50 pubmed publisher |
| Gorrell R, Guan J, Xin Y, Tafreshi M, Hutton M, McGuckin M, et al. A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system. Cell Microbiol. 2013;15:554-70 pubmed publisher |
| Cox R, Livesay S, Johnson M, Ohi M, Williams J. The human metapneumovirus fusion protein mediates entry via an interaction with RGD-binding integrins. J Virol. 2012;86:12148-60 pubmed publisher |
| Albert M, Schmidt M, Cordes N, Dorr W. Modulation of radiation-induced oral mucositis (mouse) by selective inhibition of ?1 integrin. Radiother Oncol. 2012;104:230-4 pubmed publisher |
| Deleon O, Puglise J, Liu F, Smits J, Ter Beest M, ZEGERS M. Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways. PLoS ONE. 2012;7:e41039 pubmed publisher |
| Sato Nishiuchi R, Nakano I, Ozawa A, Sato Y, Takeichi M, Kiyozumi D, et al. Polydom/SVEP1 is a ligand for integrin ?9?1. J Biol Chem. 2012;287:25615-30 pubmed publisher |
| Aljamal Naylor R, Wilson L, McIntyre S, Rossi F, Harrison B, Marsden M, et al. Allosteric modulation of beta1 integrin function induces lung tissue repair. Adv Pharmacol Sci. 2012;2012:768720 pubmed publisher |
| Yoneda A, Morgan Fisher M, Wait R, Couchman J, Wewer U. A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II. Mol Cell Biol. 2012;32:1788-804 pubmed publisher |
| Eke I, Deuse Y, Hehlgans S, Gurtner K, Krause M, Baumann M, et al. ??Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy. J Clin Invest. 2012;122:1529-40 pubmed publisher |
| Goel H, Pursell B, Standley C, Fogarty K, Mercurio A. Neuropilin-2 regulates ?6?1 integrin in the formation of focal adhesions and signaling. J Cell Sci. 2012;125:497-506 pubmed publisher |
| Riggio M, Polo M, Blaustein M, Colman Lerner A, Lüthy I, Lanari C, et al. PI3K/AKT pathway regulates phosphorylation of steroid receptors, hormone independence and tumor differentiation in breast cancer. Carcinogenesis. 2012;33:509-18 pubmed publisher |
| Tharmalingam S, Daulat A, Antflick J, Ahmed S, Nemeth E, Angers S, et al. Calcium-sensing receptor modulates cell adhesion and migration via integrins. J Biol Chem. 2011;286:40922-33 pubmed publisher |
| Rantala J, Pouwels J, Pellinen T, Veltel S, Laasola P, Mattila E, et al. SHARPIN is an endogenous inhibitor of ?1-integrin activation. Nat Cell Biol. 2011;13:1315-24 pubmed publisher |
| Mai A, Veltel S, Pellinen T, Padzik A, Coffey E, Marjomaki V, et al. Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration. J Cell Biol. 2011;194:291-306 pubmed publisher |
| Addad S, Exposito J, Faye C, Ricard Blum S, Lethias C. Isolation, characterization and biological evaluation of jellyfish collagen for use in biomedical applications. Mar Drugs. 2011;9:967-83 pubmed publisher |
| Morello V, Cabodi S, Sigismund S, Camacho Leal M, Repetto D, Volante M, et al. ?1 integrin controls EGFR signaling and tumorigenic properties of lung cancer cells. Oncogene. 2011;30:4087-96 pubmed publisher |
| Steele M, Schieler A, Kelley P, Tempero R. ?1 integrin regulates MMP-10 dependant tubulogenesis in human lymphatic endothelial cells. Matrix Biol. 2011;30:218-24 pubmed publisher |
| Lamb L, Zarif J, Miranti C. The androgen receptor induces integrin α6β1 to promote prostate tumor cell survival via NF-κB and Bcl-xL Independently of PI3K signaling. Cancer Res. 2011;71:2739-49 pubmed publisher |
| Desiderio U, Zhu X, Evans J. ADAM2 interactions with mouse eggs and cell lines expressing ?4/?9 (ITGA4/ITGA9) integrins: implications for integrin-based adhesion and fertilization. PLoS ONE. 2010;5:e13744 pubmed publisher |
| Jo M, Eastman B, Webb D, Stoletov K, Klemke R, Gonias S. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 2010;70:8948-58 pubmed publisher |
| Vickers D, Murthy S. Receptor expression changes as a basis for endothelial cell identification using microfluidic channels. Lab Chip. 2010;10:2380-6 pubmed publisher |
| Hutton M, Kaparakis Liaskos M, Turner L, Cardona A, Kwok T, Ferrero R. Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells. Infect Immun. 2010;78:4523-31 pubmed publisher |
| Skalski M, Yi Q, Kean M, Myers D, Williams K, Burtnik A, et al. Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways. BMC Cell Biol. 2010;11:62 pubmed publisher |
| Batchelder E, Yarar D. Differential requirements for clathrin-dependent endocytosis at sites of cell-substrate adhesion. Mol Biol Cell. 2010;21:3070-9 pubmed publisher |
| Wu Y, Guo X, Brandt Y, Hathaway H, Hartley R. Three-dimensional collagen represses cyclin E1 via ?1 integrin in invasive breast cancer cells. Breast Cancer Res Treat. 2011;127:397-406 pubmed publisher |
| Ishihara S, Haga H, Yasuda M, Mizutani T, Kawabata K, Shirato H, et al. Integrin beta1-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix. Biochem Biophys Res Commun. 2010;396:651-5 pubmed publisher |
| Saha A, Backert S, Hammond C, Gooz M, Smolka A. Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit. Gastroenterology. 2010;139:239-48 pubmed publisher |
| LaRusch G, Mahdi F, Shariat Madar Z, Adams G, Sitrin R, Zhang W, et al. Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis. Blood. 2010;115:5111-20 pubmed publisher |
| Chen L, Lin S, Amin S, Overbergh L, Maggiolino G, Chan L. VCAM-1 blockade delays disease onset, reduces disease severity and inflammatory cells in an atopic dermatitis model. Immunol Cell Biol. 2010;88:334-42 pubmed publisher |
| Chen P, Abacherli L, Nadler S, Wang Y, Li Q, Parks W. MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation. PLoS ONE. 2009;4:e6565 pubmed publisher |
| Hehlgans S, Eke I, Storch K, Haase M, Baretton G, Cordes N. Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells. Radiother Oncol. 2009;92:362-70 pubmed publisher |
| Gallagher S, Castorino J, Philp N. Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration. Am J Physiol Cell Physiol. 2009;296:C414-21 pubmed publisher |
| Borza C, Borza D, Pedchenko V, Saleem M, Mathieson P, Sado Y, et al. Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. J Am Soc Nephrol. 2008;19:677-84 pubmed publisher |
| Versteeg H, Schaffner F, Kerver M, Petersen H, Ahamed J, Felding Habermann B, et al. Inhibition of tissue factor signaling suppresses tumor growth. Blood. 2008;111:190-9 pubmed |
| Liang Y, Diehn M, Bollen A, Israel M, Gupta N. Type I collagen is overexpressed in medulloblastoma as a component of tumor microenvironment. J Neurooncol. 2008;86:133-41 pubmed |
| Sequeira S, Ranganathan A, Adam A, Iglesias B, Farias E, Aguirre Ghiso J. Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation. PLoS ONE. 2007;2:e615 pubmed |
| Eto D, Jones T, Sundsbak J, Mulvey M. Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli. PLoS Pathog. 2007;3:e100 pubmed |
| Zuhorn I, Kalicharan D, Robillard G, Hoekstra D. Adhesion receptors mediate efficient non-viral gene delivery. Mol Ther. 2007;15:946-53 pubmed |
| Cooper B, Brimer N, Stoler M, Vande Pol S. Suprabasal overexpression of beta-1 integrin is induced by bovine papillomavirus type 1. Virology. 2006;355:102-14 pubmed publisher |
| Pellinen T, Arjonen A, Vuoriluoto K, Kallio K, Fransen J, Ivaska J. Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins. J Cell Biol. 2006;173:767-80 pubmed |
| Sroka T, Pennington M, Cress A. Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5. Carcinogenesis. 2006;27:1748-57 pubmed |
| Park C, Zhang H, Pallavicini M, Gray J, Baehner F, Park C, et al. Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res. 2006;66:1526-35 pubmed |
| Thodeti C, Fröhlich C, Nielsen C, Takada Y, Fassler R, Albrechtsen R, et al. ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins. FEBS Lett. 2005;579:5589-95 pubmed |
| Thodeti C, Fröhlich C, Nielsen C, Holck P, Sundberg C, Kveiborg M, et al. Hierarchy of ADAM12 binding to integrins in tumor cells. Exp Cell Res. 2005;309:438-50 pubmed |
| Enserink J, Price L, Methi T, Mahic M, Sonnenberg A, Bos J, et al. The cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin. J Biol Chem. 2004;279:44889-96 pubmed |
| Dorfleutner A, Hintermann E, Tarui T, Takada Y, Ruf W. Cross-talk of integrin alpha3beta1 and tissue factor in cell migration. Mol Biol Cell. 2004;15:4416-25 pubmed |
| Pedchenko V, Zent R, Hudson B. Alpha(v)beta3 and alpha(v)beta5 integrins bind both the proximal RGD site and non-RGD motifs within noncollagenous (NC1) domain of the alpha3 chain of type IV collagen: implication for the mechanism of endothelia cell adhesion. J Biol Chem. 2004;279:2772-80 pubmed |
| Matlin K, Haus B, Zuk A. Integrins in epithelial cell polarity: using antibodies to analyze adhesive function and morphogenesis. Methods. 2003;30:235-46 pubmed |
| Liu Y, Chen B, Lu M, Zhu Y, Stemerman M, Chien S, et al. Shear stress activation of SREBP1 in endothelial cells is mediated by integrins. Arterioscler Thromb Vasc Biol. 2002;22:76-81 pubmed |
| Iba K, Albrechtsen R, Gilpin B, Frohlich C, Loechel F, Zolkiewska A, et al. The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading. J Cell Biol. 2000;149:1143-56 pubmed |
| Kortesmaa J, Yurchenco P, Tryggvason K. Recombinant laminin-8 (alpha(4)beta(1)gamma(1)). Production, purification,and interactions with integrins. J Biol Chem. 2000;275:14853-9 pubmed |
| Levy L, Broad S, Diekmann D, Evans R, Watt F. beta1 integrins regulate keratinocyte adhesion and differentiation by distinct mechanisms. Mol Biol Cell. 2000;11:453-66 pubmed |
| Hunter A, Ottoson N, Boerth N, Koretzky G, Shimizu Y. Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration. J Immunol. 2000;164:1143-7 pubmed |
| Aguirre Ghiso J, Kovalski K, Ossowski L. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J Cell Biol. 1999;147:89-104 pubmed |
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