A6 Antigen in Biliary Epithelial & Oval cells | Developmental Studies Hybridoma Bank A6 BCM product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

A6 Antigen in Biliary Epithelial & Oval cells

catalog :

A6 BCM

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

A6 BCM

application :

immunohistochemistry, immunocytochemistry

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 6

Reference
Kitade M, Factor V, Andersen J, Tomokuni A, Kaji K, Akita H, et al. Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling. Genes Dev. 2013;27:1706-17 pubmed publisher
Holczbauer A, Factor V, Andersen J, Marquardt J, Kleiner D, Raggi C, et al. Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types. Gastroenterology. 2013;145:221-231 pubmed publisher
Ishikawa T, Factor V, Marquardt J, Raggi C, Seo D, Kitade M, et al. Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice. Hepatology. 2012;55:1215-26 pubmed publisher
Factor V, Radaeva S. Oval cells--hepatocytes relationships in Dipin-induced hepatocarcinogenesis in mice. Exp Toxicol Pathol. 1993;45:239-44 pubmed
Factor V, Radaeva S, Thorgeirsson S. Origin and fate of oval cells in dipin-induced hepatocarcinogenesis in the mouse. Am J Pathol. 1994;145:409-22 pubmed
Engelhardt N, Factor V, Yasova A, Poltoranina V, Baranov V, Lasareva M. Common antigens of mouse oval and biliary epithelial cells. Expression on newly formed hepatocytes. Differentiation. 1990;45:29-37 pubmed

product information

Internal ID :

16680

Name :

A6 BCM

Depositor Name :

Factor, V.M.

Depositor Institution :

NIH

Date Deposited :

3/4/15

Allow Hybridoma Distribution :

Cells Available (legacy) :

Antigen :

A6 Antigen in Biliary Epithelial & Oval cells

Antigen Species :

Mouse

Host Species :

rat

Isotype :

RIgG2a

Positive Tested Species Reactivity :

Mouse

Initial Publication Pubmed ID :

2292360

Depositor Notes (Special Instructions) :

This antibody is applicable on cultured cells, however the epitope is lost on primary cells after enzymatic digestion. In addition to biliary epithelium, A6 recognizes a wide variety of stratified and simple epithelium of ectodermal, mesodermal and endodermal origin in adult and embryonic tissues plus primary heptocarcinoma. See Table 3 in PMID 2292360.

Collections :

Cell markers

Search Keywords :

Factor, V.M., A6 antigen in biliary epithelial/oval cells, Mouse, RIgG2a, Mouse, , , , Monoclonal

Antibody Registry ID :

AB_2618041

Immunogen :

DIPIN-treated OVAL cell lysate

Clonality :

Monoclonal

Myeloma Strain :

X-63-Ag8-653

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunohistochemistry

Immunohistochemistry Pubmed IDs :

2292360 8219714 8053498 22095660 23523670 23913923

Immunofluorescence Pubmed IDs :

22095660 23913923 30878582

Depositor Growth Medium :

F12/DMEM with 10% FCS, pen/strep, glutamax

Additional Information :

This antibody recognizes the A6 antigen in frozen sections in unfixed, acetone, ethanol, methanol and paraformaldehyde fixed sections. Also, with antigen retrieval or enzymatic digestion with Proteinase K (20ug/ml in PBS;10-30 min), formalin-fixed paraffin embedded sections are sucessful labeled. RRID:AB_2618041

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage