product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Cyclin A
catalog :
A12
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A12
reactivity :
mouse, fruit fly
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000
Sun D, Buttitta L. Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in Drosophila. Development. 2015;142:3033-45 pubmed publisher
Hassel C, Zhang B, Dixon M, Calvi B. Induction of endocycles represses apoptosis independently of differentiation and predisposes cells to genome instability. Development. 2014;141:112-23 pubmed publisher
Park J, Ma W, O Brien L, Chung E, Guo J, Cheng J, et al. Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks. Dev Cell. 2012;23:637-51 pubmed publisher
Yuan H, Chiang C, Cheng J, Salzmann V, Yamashita Y. Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells. Dev Biol. 2012;361:57-67 pubmed publisher
Papoulas O, Monzo K, Cantin G, Ruse C, Yates J, Ryu Y, et al. dFMRP and Caprin, translational regulators of synaptic plasticity, control the cell cycle at the Drosophila mid-blastula transition. Development. 2010;137:4201-9 pubmed publisher
Beam C, MOBERG K. The gang of four gene regulates growth and patterning of the developing Drosophila eye. Fly (Austin). 2010;4:104-16 pubmed
Anderson M, Jodoin J, Lee E, Hales K, Hays T, Lee L. Asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis. Mol Biol Cell. 2009;20:2709-21 pubmed publisher
Kotadia S, Kao L, Comerford S, Jones R, Hammer R, Megraw T. PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen. Oncogene. 2008;27:6334-46 pubmed publisher
Scaria G, Ramsay G, Katzen A. Two components of the Myb complex, DMyb and Mip130, are specifically associated with euchromatin and degraded during prometaphase throughout development. Mech Dev. 2008;125:646-61 pubmed publisher
Narbonne Reveau K, Senger S, Pal M, Herr A, Richardson H, Asano M, et al. APC/CFzr/Cdh1 promotes cell cycle progression during the Drosophila endocycle. Development. 2008;135:1451-61 pubmed publisher
Minakhina S, Druzhinina M, Steward R. Zfrp8, the Drosophila ortholog of PDCD2, functions in lymph gland development and controls cell proliferation. Development. 2007;134:2387-96 pubmed
Pellock B, Buff E, White K, Hariharan I. The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling. Dev Biol. 2007;304:102-15 pubmed
Sakaguchi A, Steward R. Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster. J Cell Biol. 2007;176:155-62 pubmed
Jones C, Reifegerste R, Moses K. Characterization of Drosophila mini-me, a gene required for cell proliferation and survival. Genetics. 2006;173:793-808 pubmed
Martinez A, Colomb S, Déjardin J, Bantignies F, Cavalli G. Polycomb group-dependent Cyclin A repression in Drosophila. Genes Dev. 2006;20:501-13 pubmed
Vrailas A, Moses K. Smoothened, thickveins and the genetic control of cell cycle and cell fate in the developing Drosophila eye. Mech Dev. 2006;123:151-65 pubmed
Sugimura I, Lilly M. Bruno inhibits the expression of mitotic cyclins during the prophase I meiotic arrest of Drosophila oocytes. Dev Cell. 2006;10:127-35 pubmed
Douglas R, Farahani R, Morcillo P, Kanaan A, Xu T, Haddad G. Hypoxia induces major effects on cell cycle kinetics and protein expression in Drosophila melanogaster embryos. Am J Physiol Regul Integr Comp Physiol. 2005;288:R511-21 pubmed
Furukawa K, Sugiyama S, Osouda S, Goto H, Inagaki M, Horigome T, et al. Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila. J Cell Sci. 2003;116:3811-23 pubmed
Mihaylov I, Kondo T, Jones L, Ryzhikov S, Tanaka J, Zheng J, et al. Control of DNA replication and chromosome ploidy by geminin and cyclin A. Mol Cell Biol. 2002;22:1868-80 pubmed
Ito N, Rubin G. gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle. Cell. 1999;96:529-39 pubmed
Sigrist S, Jacobs H, Stratmann R, Lehner C. Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J. 1995;14:4827-38 pubmed
Lehner C, O Farrell P. Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell. 1989;56:957-68 pubmed
product information
Internal ID :
2970
Name :
A12
Depositor Name :
Lehner, C.F.
Depositor Institution :
University of Bayreuth
Date Deposited :
2/23/00
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Cyclin A
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Drosophila
Species Tested (legacy) :
Drosophila
Initial Publication Pubmed ID :
2564316 7588612
Collections :
Cell signaling,Drosophila antigens
Search Keywords :
Lehner, Christian F., Cyclin A, Drosophila, MIgG1, Drosophila, CycA, Cyc A; cycA; CYCA; dCycA; DmcycA; Dmel CG5940; , AB_528188, monoclonal
Antigen Molecular Weight :
56 kDa
Gene :
CycA
Alternate Gene Name(s) :
Cyc A; cycA; CYCA; dCycA; DmcycA; Dmel CG5940;
Uniprot ID :
P14785
Antibody Registry ID :
AB_528188
Immunogen :
Cyclin A (a.a 6-491); recombinant
Clonality :
Monoclonal
Epitope Mapped :
No
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
2564316 16481477 10052455 22024320 18321983 17258190 16399084 12902403 16412615 16547096 20473027
Immunofluorescence Pubmed IDs :
2564316 7588612 16481477 22024320 19357193 16399084 17522156 18424081
Western Blot Pubmed IDs :
2564316 7588612 24284207 11865064 17227890 22024320 19357193 16399084 18663356 15498965 21068064
Immunoprecipitation Pubmed IDs :
11865064 16481477 22902740
DSHB Growth Medium :
RPMI
References (legacy) :
EMBO J. 12(1), 65-74.; EMBO J. 14, 4827-4838.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US