Integrin alpha-7, extracellular domain | Developmental Studies Hybridoma Bank 9.1 ITGA7 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Integrin alpha-7, extracellular domain

catalog :

9.1 ITGA7

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9.1 ITGA7

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 7

Reference
Ozeki N, Mogi M, Yamaguchi H, Hiyama T, Kawai R, Hase N, et al. Differentiation of human skeletal muscle stem cells into odontoblasts is dependent on induction of ?1 integrin expression. J Biol Chem. 2014;289:14380-91 pubmed publisher
Noro A, Sillat T, Virtanen I, Ingerpuu S, Bäck N, Konttinen Y, et al. Laminin production and basement membrane deposition by mesenchymal stem cells upon adipogenic differentiation. J Histochem Cytochem. 2013;61:719-30 pubmed publisher
Pawlikowski B, Lee L, Zuo J, Kramer R. Analysis of human muscle stem cells reveals a differentiation-resistant progenitor cell population expressing Pax7 capable of self-renewal. Dev Dyn. 2009;238:138-49 pubmed publisher
Gorfu G, Virtanen I, Hukkanen M, Lehto V, Rousselle P, Kenne E, et al. Laminin isoforms of lymph nodes and predominant role of alpha5-laminin(s) in adhesion and migration of blood lymphocytes. J Leukoc Biol. 2008;84:701-12 pubmed publisher
Ozeki N, Lim M, Yao C, Tolar M, Kramer R. alpha7 integrin expressing human fetal myogenic progenitors have stem cell-like properties and are capable of osteogenic differentiation. Exp Cell Res. 2006;312:4162-80 pubmed
Yeh M, Ziober B, Liu B, Lipkina G, Vizirianakis I, Kramer R. The beta1 cytoplasmic domain regulates the laminin-binding specificity of the alpha7X1 integrin. Mol Biol Cell. 2003;14:3507-18 pubmed
Vizirianakis I, Yao C, Chen Y, Ziober B, Tsiftsoglou A, Kramer R. Transfection of MCF-7 carcinoma cells with human integrin alpha7 cDNA promotes adhesion to laminin. Arch Biochem Biophys. 2001;385:108-16 pubmed

product information

Internal ID :

23594

Name :

9.1 ITGA7

Depositor Name :

Kramer, R.H.

Depositor Institution :

University of California at San Francisco

Date Deposited :

9/7/16

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Integrin alpha-7, extracellular domain

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG2c

Positive Tested Species Reactivity :

Human

Initial Publication Pubmed ID :

11361006

Depositor Notes (Special Instructions) :

The 9.1 antibody recognizes the extracellular domain of alpha 7 integrin in both native and denatured conformations.

Collections :

Cardiac development,Cell adhesion,Human,Skeletal muscle

Search Keywords :

Kramer, R.H., Integrin alpha-7, extracellular domain, Human, MIgG, Human, ITGA7, , , Monoclonal, Human/Skeletal muscle/Cell adhesion/Cardiac development, Immunoprecipitation/FACS/Western blot/Immunofluorescence/Function blocking, 9.1iTGA7

Antigen Molecular Weight :

128 kDa

Gene :

ITGA7

Uniprot ID :

Q13683

Antibody Registry ID :

AB_2721955

Immunogen :

Live NIH3T3 cells transfected with human alpha 7 integrin DNA

Clonality :

Monoclonal

Myeloma Strain :

Sp2/0

Epitope Mapped :

Epitope Location or Sequence :

Extracellular domain of alpha 7 integrin

Recommended Applications :

FACS,Function Blocking,Immunofluorescence,Immunoprecipitation,Western Blot

Immunofluorescence Pubmed IDs :

17054947 11361006 19097049 23900596

Western Blot Pubmed IDs :

11361006 12972542

Immunoprecipitation Pubmed IDs :

12972542 11361006

Function Blocking Pubmed IDs :

17054947 12972542 24692545

FACS Pubmed IDs :

12972542 11361006 17054947 18523231 19097049 24692545

Additional Information :

Alpha 7/beta-1 integrin is the primary laminin-1 receptor. This receptor is expressed in skeletal and cardiac muscle and certain tumor cells. RRID:AB_2721955

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage