integrin beta-1 (Xenopus) | Developmental Studies Hybridoma Bank 8C8 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

integrin beta-1 (Xenopus)

catalog :

8C8

clonality :

monoclonal

host :

house mouse

conjugate :

nonconjugated

clone name :

8C8

reactivity :

Xenopus laevis

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
western blot; Xenopus laevis; fig 7c	Gouignard N, Maccarana M, Strate I, von Stedingk K, Malmstrom A, Pera E. Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. Dis Model Mech. 2016;9:607-20 pubmed publisher
immunohistochemistry; Xenopus laevis; 1:100; fig 4	Tandon P, Wilczewski C, Williams C, Conlon F. The Lhx9-integrin pathway is essential for positioning of the proepicardial organ. Development. 2016;143:831-40 pubmed publisher
immunohistochemistry; Xenopus laevis; 1:100; fig s10	Sojka S, Amin N, Gibbs D, Christine K, Charpentier M, Conlon F. Congenital heart disease protein 5 associates with CASZ1 to maintain myocardial tissue integrity. Development. 2014;141:3040-9 pubmed publisher
	Womble M, Amin N, Nascone Yoder N. The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum. Dev Biol. 2018;439:80-91 pubmed publisher
	Zhang Z, Rankin S, Zorn A. Syndecan4 coordinates Wnt/JNK and BMP signaling to regulate foregut progenitor development. Dev Biol. 2016;416:187-199 pubmed publisher
	Langhe R, Gudzenko T, Bachmann M, Becker S, Gonnermann C, Winter C, et al. Cadherin-11 localizes to focal adhesions and promotes cell-substrate adhesion. Nat Commun. 2016;7:10909 pubmed publisher
	Rapchak C, Patel N, Hudson J, Crawford M. Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome. Biochem Cell Biol. 2015;93:396-404 pubmed publisher
	Huang Y, Niehrs C. Polarized Wnt signaling regulates ectodermal cell fate in Xenopus. Dev Cell. 2014;29:250-7 pubmed publisher
	Hedde P, Dörlich R, Blomley R, Gradl D, Oppong E, Cato A, et al. Stimulated emission depletion-based raster image correlation spectroscopy reveals biomolecular dynamics in live cells. Nat Commun. 2013;4:2093 pubmed publisher
	Zhang Z, Rankin S, Zorn A. Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol. 2013;378:1-12 pubmed publisher
	Marshall W, Katoh F, Main H, Sers N, Cozzi R. Focal adhesion kinase and beta1 integrin regulation of Na+, K+, 2Cl- cotransporter in osmosensing ion transporting cells of killifish, Fundulus heteroclitus. Comp Biochem Physiol A Mol Integr Physiol. 2008;150:288-300 pubmed publisher
	Bayaa M, Booth R, Sheng Y, Liu X. The classical progesterone receptor mediates Xenopus oocyte maturation through a nongenomic mechanism. Proc Natl Acad Sci U S A. 2000;97:12607-12 pubmed
	Cohen M, Hoffstrom B, DeSimone D. Active zones on motor nerve terminals contain alpha 3beta 1 integrin. J Neurosci. 2000;20:4912-21 pubmed
	McPhee J, Dang Y, Davidson N, Lester H. Evidence for a functional interaction between integrins and G protein-activated inward rectifier K+ channels. J Biol Chem. 1998;273:34696-702 pubmed
	Chen W, Joos T, Defoe D. Evidence for beta 1-integrins on both apical and basal surfaces of Xenopus retinal pigment epithelium. Exp Eye Res. 1997;64:73-84 pubmed
	Gawantka V, Ellinger Ziegelbauer H, Hausen P. Beta 1-integrin is a maternal protein that is inserted into all newly formed plasma membranes during early Xenopus embryogenesis. Development. 1992;115:595-605 pubmed

product information

Internal ID :

4107

Name :

8C8

Depositor Name :

Hausen, P. / Gawantka, V.

Depositor Institution :

MPI Tuebingen

Date Deposited :

4/20/94

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

integrin beta-1 (Xenopus)

Antigen Species :

Xenopus laevis

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Fish,Xenopus

Species Tested (legacy) :

Xenopus, other species not tested

Initial Publication Pubmed ID :

1385064

Depositor Notes (Special Instructions) :

8C8 doesn't recognize the reduced protein. For immunohistochemistry, formaldehyde or methanol fixation work well.

Collections :

CD antigens,Cell adhesion,Cell signaling,Extracellular matrix proteins,Xenopus

Search Keywords :

Hausen, P. / Gawantka, V., integrin beta-1 (Xenopus), Xenopus laevis , MIgG1, Xenopus/Fish, itgb1-a and itgb1-b, CD29, AB_528309, monoclonal, Cell adhesion/Cell signaling/Extracellular matrix proteins/Xenopus/Cluster Determinant antigens, Immunofluorescence/Western Blot/Immunoprecipitation

Antigen Molecular Weight :

Predicted: 86 kDa; Apparent: 100 kDa (precursor) and 115 kDa (mature protein) under non-reducing conditions and 125 kDa (precursor) and 135 kDa (mature protein) under reducing conditions

Gene :

itgb1-a and itgb1-b

Alternate Gene Name(s) :

CD29

Uniprot ID :

P12606 P12607

Antibody Registry ID :

AB_528309

Immunogen :

Protein fraction enriched in beta1-integrin precursor protein from XTC cells

Clonality :

Monoclonal

Myeloma Strain :

NS I

Epitope Mapped :

Recommended Applications :

Immunofluorescence,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes

Immunohistochemistry Pubmed IDs :

29709601

Immunofluorescence Pubmed IDs :

1385064 18455940 23803641 24780739 27235146 26952325 23562607 26150138 10864949 9093023

Western Blot Pubmed IDs :

1385064 11050156 27235146 9856991 9093023

Immunoprecipitation Pubmed IDs :

1385064 10864949 9093023

DSHB Growth Medium :

RPMI

References (legacy) :

Development 115, 595-605.; PNAS 97(23), 12607-12612.; Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 150, 288-300.

more info or order :

Developmental Studies Hybridoma Bank product webpage