product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
FMR1
catalog :
7G1-1
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7G1-1
reactivity :
mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, RNA immunoprecipitation, western blot knockout validation
more info or order :
citations: 23
Published Application/Species/Sample/Dilution | Reference |
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Westmark C, Malter J. FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol. 2007;5:e52 pubmed
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Wulczyn F, Smirnova L, Rybak A, Brandt C, Kwidzinski E, Ninnemann O, et al. Post-transcriptional regulation of the let-7 microRNA during neural cell specification. FASEB J. 2007;21:415-26 pubmed
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Price T, Flores C, Cervero F, Hargreaves K. The RNA binding and transport proteins staufen and fragile X mental retardation protein are expressed by rat primary afferent neurons and localize to peripheral and central axons. Neuroscience. 2006;141:2107-16 pubmed
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Brown V, Jin P, Ceman S, Darnell J, O Donnell W, Tenenbaum S, et al. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. Cell. 2001;107:477-87 pubmed
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product information
Internal ID :
963
Name :
7G1-1
Depositor Name :
Warren, S.T.
Depositor Institution :
Emory University
Date Deposited :
3/7/03
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
Antigen :
FMR1
Antigen Species :
Mouse
Host Species :
mouse
Isotype :
MIgG2b
Isotype for catalog (legacy) :
IgG2b
Positive Tested Species Reactivity :
Mouse,Rat
Species Tested (legacy) :
mouse, rat, not human
Initial Publication Pubmed ID :
11719188
Collections :
Cell signaling,Human,Neurodevelopment
Search Keywords :
Warren, Stephen T., FMR1, Mouse, MIgG2b, Mouse/Rat, Fmr1, FMRP, Fmr-1, AB_528251, monoclonal
Antigen Molecular Weight :
~70-80kDa
Gene :
Fmr1
Alternate Gene Name(s) :
FMRP, Fmr-1
Uniprot ID :
P35922
Antibody Registry ID :
AB_528251
Immunogen :
Fmrp-6X-his fusion protein.
Clonality :
Monoclonal
Myeloma Strain :
Sp2/0
Epitope Mapped :
Yes
Epitope Location or Sequence :
a.a. 354-368 [seq: KHLDTKENTHFSQPN}
Epitope Map PubMed ID :
11719188
Recommended Applications :
Immunofluorescence,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
yes
Immunohistochemistry Pubmed IDs :
19193898
Immunofluorescence Pubmed IDs :
24175909 22201125 19193898
Western Blot Pubmed IDs :
22737234 21957233 21273427 21215802 22737234 16809002 20011099
Immunoprecipitation Pubmed IDs :
11719188 22737234 24709664 23831253 20685971 22737234 21784246 21228181 22343717 20702695 17298186 18511554 20011099 18410515 30056576
Gel Supershift Pubmed IDs :
17167072
DSHB Growth Medium :
Iscove's
References (legacy) :
Cell 107, 477-487.; PLoS One 7(6):e39338.
more info or order :
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Developmental Studies Hybridoma Bank
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