product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
L-CAM/E-cadherin, chicken
catalog :
7D6
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7D6
reactivity :
chicken
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
citations: 15
Reference
Chaussé A, Grépinet O, Bottreau E, Robert V, Hennequet Antier C, Lalmanach A, et al. Susceptibility to Salmonella carrier-state: a possible Th2 response in susceptible chicks. Vet Immunol Immunopathol. 2014;159:16-28 pubmed publisher
Thomas W, Boscher C, Chu Y, Cuvelier D, Martinez Rico C, Seddiki R, et al. ?-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength. J Biol Chem. 2013;288:4957-69 pubmed publisher
Burns J, Collado M, Oliver E, Corwin J. Specializations of intercellular junctions are associated with the presence and absence of hair cell regeneration in ears from six vertebrate classes. J Comp Neurol. 2013;521:1430-48 pubmed publisher
Chaussé A, Grépinet O, Bottreau E, Le Vern Y, Menanteau P, Trotereau J, et al. Expression of Toll-like receptor 4 and downstream effectors in selected cecal cell subpopulations of chicks resistant or susceptible to Salmonella carrier state. Infect Immun. 2011;79:3445-54 pubmed publisher
Boswell B, VanSlyke J, Musil L. Regulation of lens gap junctions by Transforming Growth Factor beta. Mol Biol Cell. 2010;21:1686-97 pubmed publisher
Thompson J, Wong L, Lau P, Bannigan J. Adherens junction breakdown in the periderm following cadmium administration in the chick embryo: distribution of cadherins and associated molecules. Reprod Toxicol. 2008;25:39-46 pubmed
Warchol M. Characterization of supporting cell phenotype in the avian inner ear: implications for sensory regeneration. Hear Res. 2007;227:11-8 pubmed
Igyártó B, Lackó E, Oláh I, Magyar A. Characterization of chicken epidermal dendritic cells. Immunology. 2006;119:278-88 pubmed
Pérez Pomares J, Mironov V, Guadix J, Macías D, Markwald R, Muñoz Chápuli R. In vitro self-assembly of proepicardial cell aggregates: an embryonic vasculogenic model for vascular tissue engineering. Anat Rec A Discov Mol Cell Evol Biol. 2006;288:700-13 pubmed
Chu Y, Eder O, Thomas W, Simcha I, Pincet F, Ben Ze ev A, et al. Prototypical type I E-cadherin and type II cadherin-7 mediate very distinct adhesiveness through their extracellular domains. J Biol Chem. 2006;281:2901-10 pubmed
Shimizu Y, Yamamichi N, Saitoh K, Watanabe A, Ito T, Yamamichi Nishina M, et al. Kinetics of v-src-induced epithelial-mesenchymal transition in developing glandular stomach. Oncogene. 2003;22:884-93 pubmed
Yamagata M, Herman J, Sanes J. Lamina-specific expression of adhesion molecules in developing chick optic tectum. J Neurosci. 1995;15:4556-71 pubmed
Redies C, Muller H. Similarities in structure and expression between mouse P-cadherin, chicken B-cadherin and frog XB/U-cadherin. Cell Adhes Commun. 1994;2:511-20 pubmed
Gallin W, Edelman G, Cunningham B. Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells. Proc Natl Acad Sci U S A. 1983;80:1038-42 pubmed
Marsh R, Gallin W. Structural variants of the neural cell adhesion molecule (N-CAM) in developing feathers. Dev Biol. 1992;150:171-84 pubmed
product information
Internal ID :
3226
Name :
7D6
Depositor Name :
Gallin, W.
Depositor Institution :
University of Alberta
Date Deposited :
5/13/91
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
L-CAM/E-cadherin, chicken
Antigen Species :
Chicken
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Chicken
Species Tested (legacy) :
does not cross react with any mammalian species tested, nor with Xenopus laevis nor with any invertebrate species tested
Initial Publication Pubmed ID :
6573655
Depositor Notes (Special Instructions) :
Does not cross-react with any mammalian species tested, nor with Xenopus laevis, nor with any invertebrate species tested. Doesn't appear to work for western blotting. Doesn't appear to affect L-CAM function. Stains nearly all epithelial cells.
Collections :
CD antigens,Cell adhesion
Search Keywords :
Gallin, W., L-CAM/E-cadherin, chicken, Chicken, MIgG1, Chicken, CDH1, Cadherin-1, AB_528115, monoclonal, Cell adhesion/Cluster Determinant antigens, Immunohistochemistry/Immunofluorescence/Immunoprecipitation/FACS
Antigen Molecular Weight :
Predicted: 98 kDa; Apparent: 124 kDa
Gene :
CDH1
Alternate Gene Name(s) :
Cadherin-1
Uniprot ID :
P08641
Antibody Registry ID :
AB_528115
Immunogen :
81 kDa N-terminal tryptic fragment of L-CAM from chicken liver plasma membranes.
Immunogen Sequence :
Partial protein
Clonality :
Monoclonal
Myeloma Strain :
P3U
Epitope Mapped :
Yes
Epitope Location or Sequence :
Extracellular domain
Recommended Applications :
FACS,Immunofluorescence,Immunohistochemistry,Immunoprecipitation
Immunoblotting (legacy) :
No
Immunohistochemistry Pubmed IDs :
1537432 18031986
Immunofluorescence Pubmed IDs :
7790923 12584568 17081713 16761281 23124808 16889640 20357001
Immunoprecipitation Pubmed IDs :
7743137
FACS Pubmed IDs :
16253998 21628520 24694400
Pubmed IDs :
23266828
DSHB Growth Medium :
Iscove's
References (legacy) :
Proc. Nat'l. Acad. Sci. USA 80, 1038-1042.; Dev. Biol. 102, 61-78.; Proc. Nat'l Acad. Sci. USA 84, 2808-2812.; Cell Adhesion and Comm. 2, 511-520.; J. Biol. Chem. 288(7), 4957-5969.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US