product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
cadherin, C- (3)
catalog :
6B6
clonality :
monoclonal
host :
house mouse
conjugate :
nonconjugated
clone name :
6B6
reactivity :
Xenopus laevis
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; Xenopus laevis; loading ...
Herbomel G, Hatte G, Roul J, Padilla Parra S, Tassan J, Tramier M. Actomyosin-generated tension on cadherin is similar between dividing and non-dividing epithelial cells in early Xenopus laevis embryos. Sci Rep. 2017;7:45058 pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:50; loading ...; fig 6c
  • western blot; Xenopus laevis; 1:100; loading ...; fig 6b
Balashova O, Visina O, Borodinsky L. Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation. Development. 2017;144:1518-1530 pubmed publisher
  • immunocytochemistry; Xenopus laevis; fig 7
  • western blot; Xenopus laevis; fig 7
Li D, Sinha T, Ajima R, Seo H, Yamaguchi T, Wang J. Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment. Dev Biol. 2016;412:18-31 pubmed publisher
Forecki J, Van Antwerp D, Lujan S, Merzdorf C. Roles for Xenopus aquaporin-3b (aqp3.L) during gastrulation: Fibrillar fibronectin and tissue boundary establishment in the dorsal margin. Dev Biol. 2018;433:3-16 pubmed publisher
Wang X, Sun J, Li C, Mao B. EphA7 modulates apical constriction of hindbrain neuroepithelium during neurulation in Xenopus. Biochem Biophys Res Commun. 2016;479:759-765 pubmed publisher
Zhang Z, Rankin S, Zorn A. Syndecan4 coordinates Wnt/JNK and BMP signaling to regulate foregut progenitor development. Dev Biol. 2016;416:187-199 pubmed publisher
Pfister K, Shook D, Chang C, Keller R, Skoglund P. Molecular model for force production and transmission during vertebrate gastrulation. Development. 2016;143:715-27 pubmed publisher
Huang C, Kratzer M, Wedlich D, Kashef J. E-cadherin is required for cranial neural crest migration in Xenopus laevis. Dev Biol. 2016;411:159-171 pubmed publisher
Miyagi A, Negishi T, Yamamoto T, Ueno N. G protein-coupled receptors Flop1 and Flop2 inhibit Wnt/β-catenin signaling and are essential for head formation in Xenopus. Dev Biol. 2015;407:131-44 pubmed publisher
Wang S, Cha S, Zorn A, Wylie C. Par6b regulates the dynamics of apicobasal polarity during development of the stratified Xenopus epidermis. PLoS ONE. 2013;8:e76854 pubmed publisher
Chartrain I, Le Page Y, Hatte G, Körner R, Kubiak J, Tassan J. Cell-cycle dependent localization of MELK and its new partner RACK1 in epithelial versus mesenchyme-like cells in Xenopus embryo. Biol Open. 2013;2:1037-48 pubmed publisher
Zhang Z, Rankin S, Zorn A. Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev Biol. 2013;378:1-12 pubmed publisher
Kraft B, Berger C, Wallkamm V, Steinbeisser H, Wedlich D. Wnt-11 and Fz7 reduce cell adhesion in convergent extension by sequestration of PAPC and C-cadherin. J Cell Biol. 2012;198:695-709 pubmed publisher
Nandadasa S, Tao Q, Shoemaker A, Cha S, Wylie C. Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis. PLoS ONE. 2012;7:e38756 pubmed publisher
Ninomiya H, David R, Damm E, Fagotto F, Niessen C, Winklbauer R. Cadherin-dependent differential cell adhesion in Xenopus causes cell sorting in vitro but not in the embryo. J Cell Sci. 2012;125:1877-83 pubmed publisher
Luu O, David R, Ninomiya H, Winklbauer R. Large-scale mechanical properties of Xenopus embryonic epithelium. Proc Natl Acad Sci U S A. 2011;108:4000-5 pubmed publisher
Suzuki M, Hara Y, Takagi C, Yamamoto T, Ueno N. MID1 and MID2 are required for Xenopus neural tube closure through the regulation of microtubule organization. Development. 2010;137:2329-39 pubmed publisher
Li Y, Rankin S, Sinner D, Kenny A, Krieg P, Zorn A. Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev. 2008;22:3050-63 pubmed publisher
Brieher W, Gumbiner B. Regulation of C-cadherin function during activin induced morphogenesis of Xenopus animal caps. J Cell Biol. 1994;126:519-27 pubmed
product information
Internal ID :
3801
Name :
6B6
Depositor Name :
Gumbiner, B.M.
Depositor Institution :
University of Virginia
Depositor Website :
http://www.seattlechildrens.org/research/developmental-biology-regenerative-medicine/gumbiner-lab/
Date Deposited :
5/7/93
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
cadherin, C- (3)
Antigen Species :
Xenopus
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1
Positive Tested Species Reactivity :
Xenopus
Species Tested (legacy) :
Xenopus, other amphibia not tested
Initial Publication Pubmed ID :
8034750
Depositor Notes (Special Instructions) :
This antibody blocks aggregation of embryonic blastomeres.
Collections :
Cell adhesion,Xenopus
Search Keywords :
Gumbiner, B.M., cadherin, C- (3), Xenopus, MIgG1, Xenopus, cdh3.L, , AB_528113, Monoclonal , Xenopus/Cell adhesion, Immunofluorescence/FFPE/Western blot/Immunoprecipitation/Function Blocking
Antigen Molecular Weight :
120 kDa
Gene :
cdh3.L
Uniprot ID :
P33148
Antibody Registry ID :
AB_528113
Immunogen :
EC2 extracellular domain - GST fusion protein
Immunogen Sequence :
Extracellular domain
Clonality :
Monoclonal
Myeloma Strain :
SP-2/0
Epitope Mapped :
No
Recommended Applications :
FFPE,Function Blocking,Immunofluorescence,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
28255006 27235146 26884399 23562607 22328523 21368110 20534674 18981481
Immunofluorescence Pubmed IDs :
27693790 8034750 28327558 26916252 24204686 24167714 22908314 22719936 29113748 26879760
Western Blot Pubmed IDs :
8034750 28255006 27235146 26916252 26884399 24204686 26244992 22908314 22719936
Immunoprecipitation Pubmed IDs :
8034750
FFPE Pubmed IDs :
27693790 28255006
Function Blocking Pubmed IDs :
8034750
Additional Information :
RRID: AB_528113
DSHB Growth Medium :
RPMI
References (legacy) :
J. Cell Biol. 126(2), 519-527.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US