Cadherin, N- (neural) | Developmental Studies Hybridoma Bank 6B3 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Cadherin, N- (neural)

catalog :

6B3

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6B3

reactivity :

human, chicken, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; chicken; 1:5; loading ...; fig 2a	Schill E, Lake J, Tusheva O, Nagy N, Bery S, Foster L, et al. Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. Dev Biol. 2016;409:473-88 pubmed publisher
immunohistochemistry; human	Hjorten R, Hansen U, Underwood R, Telfer H, Fernandes R, Krakow D, et al. Type XXVII collagen at the transition of cartilage to bone during skeletogenesis. Bone. 2007;41:535-42 pubmed
	Todd L, Suarez L, Squires N, Zelinka C, Gribbins K, Fischer A. Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina. J Comp Neurol. 2016;524:74-89 pubmed publisher
	Cheng Y, Wang X, Wang G, Li Y, Chen Y, Chuai M, et al. Effects of Antitumor Drug Sorafenib on Chick Embryo Development. Anat Rec (Hoboken). 2015;298:1271-81 pubmed publisher
	Welsh I, Thomsen M, Gludish D, Alfonso Parra C, Bai Y, Martin J, et al. Integration of left-right Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2. Dev Cell. 2013;26:629-44 pubmed publisher
	Lancaster M, Renner M, Martin C, Wenzel D, Bicknell L, Hurles M, et al. Cerebral organoids model human brain development and microcephaly. Nature. 2013;501:373-9 pubmed publisher
	Akbareian S, Nagy N, Steiger C, Mably J, Miller S, Hotta R, et al. Enteric neural crest-derived cells promote their migration by modifying their microenvironment through tenascin-C production. Dev Biol. 2013;382:446-56 pubmed publisher
	Sakai N, Insolera R, Sillitoe R, Shi S, Kaprielian Z. Axon sorting within the spinal cord marginal zone via Robo-mediated inhibition of N-cadherin controls spinocerebellar tract formation. J Neurosci. 2012;32:15377-87 pubmed publisher
	Nagy N, Burns A, Goldstein A. Immunophenotypic characterization of enteric neural crest cells in the developing avian colorectum. Dev Dyn. 2012;241:842-51 pubmed publisher
	Haller R, Schwanbeck R, Martini S, Bernoth K, Kramer J, Just U, et al. Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation. Cell Death Differ. 2012;19:461-9 pubmed publisher
	Yang X, Chrisman H, Weijer C. PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development. 2008;135:3521-30 pubmed publisher
	George Weinstein M, Gerhart J, Blitz J, Simak E, Knudsen K. N-cadherin promotes the commitment and differentiation of skeletal muscle precursor cells. Dev Biol. 1997;185:14-24 pubmed

product information

Internal ID :

2893

Name :

6B3

Depositor Name :

Knudsen, K.A.

Depositor Institution :

Lankenau Institute for Medical Research

Date Deposited :

10/25/05

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Cadherin, N- (neural)

Antigen Species :

Chicken

Host Species :

mouse

Isotype :

MIgG1, kappa light chain

Isotype for catalog (legacy) :

IgG1, kappa light chain

Positive Tested Species Reactivity :

Chicken,Zebrafish

Species Tested (legacy) :

chicken (does not recognize mouse N-cadherin)

Initial Publication Pubmed ID :

9169046

Depositor Notes (Special Instructions) :

This antibody does not recognize other cadherins including R-cadherin or mouse N-cadherin.

Collections :

Cardiac development,Cell adhesion,Cell signaling,Cytoskeleton,Neurodevelopment

Search Keywords :

K.A. Knudsen, Cadherin, N- (neural), Chicken, MIgG1, kappa light chain, Chicken, CDH2, , AB_528118, Monoclonal, Cytoskeletal elements , Immunohistochemistry/Immunofluorescence/Western blot/Immunoprecipitation/Function blocking

Antigen Molecular Weight :

Predicted: 82 kDa; Apparent: 135 kDa (full length), 100-kDa (extracellular fragment)

Gene :

CDH2

Uniprot ID :

P10288

Antibody Registry ID :

AB_528118

Immunogen :

Day 11 chick embryo heart extract

Immunogen Sequence :

Affinity purified N-cadherin/catenin complex

Clonality :

Monoclonal

Myeloma Strain :

P3/NSI/1-AG4-1

Epitope Mapped :

Yes

Epitope Location or Sequence :

The antibody binds the extracellular domain of N-cadherin.

Recommended Applications :

Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes

Immunohistochemistry Pubmed IDs :

22411589 23958436 23995685 23115176 18832396 26586201 25810088

Immunofluorescence Pubmed IDs :

9169046 22411589 23958436 24091014 21869831 21869831 26053997 26586201

Western Blot Pubmed IDs :

9169046

Immunoprecipitation Pubmed IDs :

9169046 23958436

Function Blocking Pubmed IDs :

9169046

Additional Information :

RRID:AB_528118

DSHB Growth Medium :

Iscove's

References (legacy) :

Dev. Biol. 185, 14-24.; Dev. Dyn. 241, 842-851.

more info or order :

Developmental Studies Hybridoma Bank product webpage