Tau | Developmental Studies Hybridoma Bank 5A6 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

Tau

catalog :

5A6

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5A6

reactivity :

degu, human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; degu; 1:100; fig 5	Du L, Chang L, Ardiles A, Tapia Rojas C, Araya J, Inestrosa N, et al. Alzheimer's Disease-Related Protein Expression in the Retina of Octodon degus. PLoS ONE. 2015;10:e0135499 pubmed publisher
western blot; human; 1:150; fig 3e	Johnson Kerner B, Ahmad F, Diaz A, Greene J, Gray S, Samulski R, et al. Intermediate filament protein accumulation in motor neurons derived from giant axonal neuropathy iPSCs rescued by restoration of gigaxonin. Hum Mol Genet. 2015;24:1420-31 pubmed publisher
	Mertens J, Stüber K, Poppe D, Doerr J, Ladewig J, Brüstle O, et al. Embryonic stem cell-based modeling of tau pathology in human neurons. Am J Pathol. 2013;182:1769-79 pubmed publisher
	Chow K, Guan H, Hersh L. Aminopeptidases do not directly degrade tau protein. Mol Neurodegener. 2010;5:48 pubmed publisher
	Daubert E, Heffron D, Mandell J, Condron B. Serotonergic dystrophy induced by excess serotonin. Mol Cell Neurosci. 2010;44:297-306 pubmed publisher
	Blard O, Feuillette S, Bou J, Chaumette B, Frebourg T, Campion D, et al. Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila. Hum Mol Genet. 2007;16:555-66 pubmed
	Vershinin M, Carter B, Razafsky D, King S, Gross S. Multiple-motor based transport and its regulation by Tau. Proc Natl Acad Sci U S A. 2007;104:87-92 pubmed
	Horowitz P, Patterson K, Guillozet Bongaarts A, Reynolds M, Carroll C, Weintraub S, et al. Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. J Neurosci. 2004;24:7895-902 pubmed
	Lesort M, Jope R, Johnson G. Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. J Neurochem. 1999;72:576-84 pubmed
	Johnson G, Seubert P, Cox T, Motter R, Brown J, Galasko D. The tau protein in human cerebrospinal fluid in Alzheimer's disease consists of proteolytically derived fragments. J Neurochem. 1997;68:430-3 pubmed

product information

Internal ID :

2725

Name :

5A6

Depositor Name :

Johnson, G.V.W.

Depositor Institution :

University of Rochester Medical Center

Date Deposited :

10/4/00

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

Tau

Antigen Species :

Human

Host Species :

mouse

Isotype :

MIgG1

Isotype for catalog (legacy) :

IgG1

Positive Tested Species Reactivity :

Drosophila,Human

Species Tested (legacy) :

human

Initial Publication Pubmed ID :

8978756

Collections :

Cytoskeleton,Drosophila antigens,Human,Neurodevelopment,Stem cell

Search Keywords :

Johnson, Gail V.W., Tau, Human, MIgG1, Human/Drosophila, MAPT, MAPTL, MTBT1, TAU, AB_528487, monoclonal

Antigen Molecular Weight :

45-58 kDa

Gene :

MAPT

Alternate Gene Name(s) :

MAPTL, MTBT1, TAU

Uniprot ID :

P10636

Antibody Registry ID :

AB_528487

Immunogen :

human recombinant/longest brain isoform 441aa

Clonality :

Monoclonal

Epitope Mapped :

Epitope Location or Sequence :

19-46

Epitope Map PubMed ID :

15356202

Recommended Applications :

Immunofluorescence,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes

Immunofluorescence Pubmed IDs :

20394820 30571694 30579783

Western Blot Pubmed IDs :

23499461 8978756 9930729 17309878 17190808

Immunoprecipitation Pubmed IDs :

8978756 21054848

DSHB Growth Medium :

RPMI

References (legacy) :

J. Neurochem. 68, 430-433.; Brain Res. 798(1-2), 173-183.; J. Neurochem. 72, 576-584.; J. Neurochem. 83, 176-185.; Mol. Neurodegener. 5:48.

more info or order :

Developmental Studies Hybridoma Bank product webpage