product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Engrail-1
catalog :
4G11
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G11
reactivity :
mouse, chicken
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig s7e
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig s6b
Li Y, Tzatzalos E, Kwan K, Grumet M, Cai L. Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development. Sci Rep. 2016;6:38665 pubmed publisher
  • immunohistochemistry; mouse; 1:50
Huettl R, Eckstein S, Stahl T, Petricca S, Ninkovic J, Götz M, et al. Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development. Dev Biol. 2016;413:86-103 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:25; loading ...; fig 6k
Zou M, Luo H, Xiang M. Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015;244:86-97 pubmed publisher
Alvarez Saavedra M, De Repentigny Y, Lagali P, Raghu Ram E, Yan K, Hashem E, et al. Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. Nat Commun. 2014;5:4181 pubmed publisher
Ganat Y, Calder E, Kriks S, Nelander J, Tu E, Jia F, et al. Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. J Clin Invest. 2012;122:2928-39 pubmed publisher
Stam F, Hendricks T, Zhang J, Geiman E, Francius C, Labosky P, et al. Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012;139:179-90 pubmed publisher
Skaggs K, Martin D, Novitch B. Regulation of spinal interneuron development by the Olig-related protein Bhlhb5 and Notch signaling. Development. 2011;138:3199-211 pubmed publisher
Yang M, Cagle M, Honig M. Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn. J Comp Neurol. 2010;518:2818-40 pubmed publisher
Satoh A, Makanae A, Wada N. The apical ectodermal ridge (AER) can be re-induced by wounding, wnt-2b, and fgf-10 in the chicken limb bud. Dev Biol. 2010;342:157-68 pubmed publisher
Wizenmann A, Brunet I, Lam J, Sonnier L, Beurdeley M, Zarbalis K, et al. Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo. Neuron. 2009;64:355-366 pubmed publisher
Ferri A, Lin W, Mavromatakis Y, Wang J, Sasaki H, Whitsett J, et al. Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner. Development. 2007;134:2761-9 pubmed
Lesaffre B, Joliot A, Prochiantz A, Volovitch M. Direct non-cell autonomous Pax6 activity regulates eye development in the zebrafish. Neural Dev. 2007;2:2 pubmed
Chung S, Shin B, Hedlund E, Pruszak J, Ferree A, Kang U, et al. Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation. J Neurochem. 2006;97:1467-80 pubmed
Sanchez Pernaute R, Studer L, Ferrari D, Perrier A, Lee H, Vinuela A, et al. Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem Cells. 2005;23:914-22 pubmed
Ericson J, Rashbass P, Schedl A, Brenner Morton S, Kawakami A, van Heyningen V, et al. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell. 1997;90:169-80 pubmed
product information
Internal ID :
2503
Name :
4G11
Depositor Name :
Jessell, T.M. / Brenner-Morton, S.
Depositor Institution :
HHMI/Columbia University
Date Deposited :
7/9/97
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Engrail-1
Antigen Species :
Chicken
Host Species :
mouse
Isotype :
MIgG1
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Fish,Zebrafish
Species Tested (legacy) :
zebrafish, fish
Initial Publication Pubmed ID :
9230312
Collections :
Human,Neurodevelopment,Transcription factors
Search Keywords :
Jessell, Thomas M / Brenner-Morton, Susan, Engrail-1, Chicken, MIgG1, Chicken/Rat/Mouse/Human, EN1, Gg-En1/En-1/en-3, AB_2314371, monoclonal
Gene :
EN1
Alternate Gene Name(s) :
Gg-En1/En-1/en-3
Uniprot ID :
Q05916
Antibody Registry ID :
AB_2314371
Immunogen :
peptide
Immunogen Sequence :
NFFIDNILRPDFG
Clonality :
Monoclonal
Myeloma Strain :
NS-1
Epitope Mapped :
Yes
Recommended Applications :
Immunofluorescence,Immunohistochemistry
Immunohistochemistry Pubmed IDs :
17596284 20347761 17229313
Immunofluorescence Pubmed IDs :
9230312 19914184 15941857 16696855 22115757 22751106 20506477
Pubmed IDs :
21750031
DSHB Growth Medium :
Iscove's
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US