neuronal marker (TAG-1) | Developmental Studies Hybridoma Bank 4D7/TAG1 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

neuronal marker (TAG-1)

catalog :

4D7/TAG1

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4D7/TAG1

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section, immunohistochemistry - free floating section

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; loading ...; fig 1 - s2b	Baba K, Yoshida W, Toriyama M, Shimada T, Manning C, Saito M, et al. Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance. elife. 2018;7: pubmed publisher
immunohistochemistry; mouse; 1:100; loading ...; tbl 1	Wang L, Yu C, Wang J, Leung P, Ma D, Zhao H, et al. Nogo-B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord. J Comp Neurol. 2017;525:2915-2928 pubmed publisher
immunohistochemistry - frozen section; mouse	Nguyen H, Ostendorf A, Satz J, Westra S, Ross Barta S, Campbell K, et al. Glial scaffold required for cerebellar granule cell migration is dependent on dystroglycan function as a receptor for basement membrane proteins. Acta Neuropathol Commun. 2013;1:58 pubmed publisher
immunohistochemistry - free floating section; mouse; 1:40	Tong K, Kwan K. Common partner Smad-independent canonical bone morphogenetic protein signaling in the specification process of the anterior rhombic lip during cerebellum development. Mol Cell Biol. 2013;33:1925-37 pubmed publisher
immunohistochemistry - frozen section; mouse	Yip Y, Capriotti C, Drill E, Tsai L, Yip J. Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord. J Comp Neurol. 2007;503:297-307 pubmed
	Huang C, Lien C, Cheng C, Yen T, Chen C, Tsaur M. K+ Channel Kv3.4 Is Essential for Axon Growth by Limiting the Influx of Ca2+ into Growth Cones. J Neurosci. 2017;37:4433-4449 pubmed publisher
	Dhaunchak A, Becker C, Schulman H, de Faria O, Rajasekharan S, Banwell B, et al. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Ann Neurol. 2012;71:601-13 pubmed publisher
	Chen Y, Magnani D, Theil T, Pratt T, Price D. Evidence that descending cortical axons are essential for thalamocortical axons to cross the pallial-subpallial boundary in the embryonic forebrain. PLoS ONE. 2012;7:e33105 pubmed publisher
	Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, et al. Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proc Natl Acad Sci U S A. 2009;106:8302-7 pubmed publisher
	Hatanaka Y, Matsumoto T, Yanagawa Y, Fujisawa H, Murakami F, Masu M. Distinct roles of neuropilin 1 signaling for radial and tangential extension of callosal axons. J Comp Neurol. 2009;514:215-25 pubmed publisher
	Wu K, Zippin J, Huron D, Kamenetsky M, Hengst U, Buck J, et al. Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nat Neurosci. 2006;9:1257-64 pubmed
	Williams S, Grumet M, Colman D, Henkemeyer M, Mason C, Sakurai T. A role for Nr-CAM in the patterning of binocular visual pathways. Neuron. 2006;50:535-47 pubmed
	Ivins J, Parry M, Long D. A novel cAMP-dependent pathway activates neuronal integrin function in retinal neurons. J Neurosci. 2004;24:1212-6 pubmed
	Dodd J, Morton S, Karagogeos D, Yamamoto M, Jessell T. Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron. 1988;1:105-16 pubmed

product information

Internal ID :

1168

Name :

4D7/TAG1

Depositor Name :

Yamamoto, M.

Depositor Institution :

University of Tsukuba

Date Deposited :

2/2/96

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

neuronal marker (TAG-1)

Antigen Species :

Rat

Host Species :

mouse

Isotype :

MIgM

Isotype for catalog (legacy) :

IgM

Positive Tested Species Reactivity :

Mouse,Rat

Species Tested (legacy) :

rat, mouse, but does not react with chick

Initial Publication Pubmed ID :

3272160

Depositor Notes (Special Instructions) :

Blots without reducing agents/ IHC using 4% parafolmadehyde fixation.

Collections :

Cell adhesion,Neurodevelopment

Search Keywords :

Yamamoto, Miyuki, Neuronal marker (TAG-1), Rat, MIgM, Rat/Mouse, Cntn2, TAG-1, TAG-564, TAG1, Tax, AB_2315433, monoclonal

Antigen Molecular Weight :

Predicted: 135 kDa

Gene :

Cntn2

Alternate Gene Name(s) :

TAG-1, TAG-564, TAG1, Tax

Uniprot ID :

P22063

Antibody Registry ID :

AB_2315433

Synonyms (Alternate Clone Names) :

Contactin-2

Immunogen :

Brain (rat fetal) lysate.

Clonality :

Monoclonal

Myeloma Strain :

NS-1

Epitope Mapped :

Recommended Applications :

FFPE,Function Blocking,Immunohistochemistry,Immunoprecipitation,Western Blot

Immunoblotting (legacy) :

Yes, without reducing agents

Immunohistochemistry Pubmed IDs :

16964251 16701205 19296474 14762139

Immunofluorescence Pubmed IDs :

16964251 17492640

Western Blot Pubmed IDs :

22473675

FFPE Pubmed IDs :

19296474

Function Blocking Pubmed IDs :

19416878 19296474

DSHB Growth Medium :

Iscove's

References (legacy) :

Neuron 1, 105-116.; Cell 87, 1001-1014.; J. Comp. Neurol. 409, 285-298.; Cell Tissue Res. 303, 159-172.; J. Comp. Neurol. 439, 368-383.; Science 297(5586), 1525-1531.; Neuron 36, 843-854.; Proc. Japan Acad. Ser. B 79(7), 223-226.; PNAS 101(5), 1211-1216.; Mol. Cell. Neurosci. 26, 390-405.; J. Comp. Neurol. 497, 734-750.; Cell 130, 1-15.; Development 138, 4979-4990.

more info or order :

Developmental Studies Hybridoma Bank product webpage