HNK-1 carbohydrate epitope | Developmental Studies Hybridoma Bank 3H5 product information

product summary

company name :

Developmental Studies Hybridoma Bank

product type :

antibody

product name :

HNK-1 carbohydrate epitope

catalog :

3H5

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3H5

reactivity :

hamsters

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Developmental Studies Hybridoma Bank product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; hamsters; 1:100; fig s1	Schiffmacher A, Padmanabhan R, Jhingory S, Taneyhill L. Cadherin-6B is proteolytically processed during epithelial-to-mesenchymal transitions of the cranial neural crest. Mol Biol Cell. 2014;25:41-54 pubmed publisher
	Liu J, Cheung M. Neural crest stem cells and their potential therapeutic applications. Dev Biol. 2016;419:199-216 pubmed publisher
	Modrell M, Hockman D, Uy B, Buckley D, Sauka Spengler T, Bronner M, et al. A fate-map for cranial sensory ganglia in the sea lamprey. Dev Biol. 2014;385:405-16 pubmed
	Kerosuo L, Bronner M. Biphasic influence of Miz1 on neural crest development by regulating cell survival and apical adhesion complex formation in the developing neural tube. Mol Biol Cell. 2014;25:347-55 pubmed publisher
	Rogers C, Saxena A, Bronner M. Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT. J Cell Biol. 2013;203:835-47 pubmed publisher
	Juarez M, Reyes M, Coleman T, Rotenstein L, Sao S, Martinez D, et al. Characterization of the trunk neural crest in the bamboo shark, Chiloscyllium punctatum. J Comp Neurol. 2013;521:3303-20 pubmed publisher

product information

Internal ID :

6208

Name :

3H5

Depositor Name :

Halfter, W.M.

Depositor Institution :

Department of Neurobiology, University of Pittsburgh

Date Deposited :

9/14/09

Allow Hybridoma Distribution :

Yes

Cells Available (legacy) :

Yes

Antigen :

HNK-1 carbohydrate epitope

Antigen Species :

chicken

Host Species :

mouse

Isotype :

MIgM

Isotype for catalog (legacy) :

IgM

Positive Tested Species Reactivity :

Chicken,Human,Lamprey,Shark

Species Tested (legacy) :

chick and human

Initial Publication Pubmed ID :

23640803

Depositor Notes (Special Instructions) :

The HNK-1 epitope is a N-linked carbohydrate marker of neural crest cells and of a subset of lymphocytes. This marker is also known as CD57.

Collections :

CD antigens,Neurodevelopment

Search Keywords :

Halfter, W.M., HNK-1 carbohydrate epitope, chicken, MIgM, chicken/human/shark/lamprey, , , AB_2314644, monoclonal, Neurodevelopment/Cluster Determinant antigens, Immunohistochemistry/Immunofluorescence, HNK1

Antibody Registry ID :

AB_2314644

Immunogen :

Chicken optic nerve (E10)

Clonality :

Monoclonal

Myeloma Strain :

X63Ag8.653

Epitope Mapped :

Yes

Epitope Location or Sequence :

SO4-3GlcAb1-3Galb1-4GlcNAc

Recommended Applications :

Immunofluorescence,Immunohistochemistry

Immunohistochemistry Pubmed IDs :

24307680

Immunofluorescence Pubmed IDs :

27640086 23640803 24297751 24513489

Additional Information :

3H5 is a mouse hybridoma that was generated against chick optic nerve, and is not a subclone of the VC1.1 hybridoma which is a mouse IgM and also recognizes the HNK-1 epitope.

DSHB Growth Medium :

Iscove's

more info or order :

Developmental Studies Hybridoma Bank product webpage