product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Lsamp (Lamp)
catalog :
2G9
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G9
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - free floating section
more info or order :
citations: 15
| Published Application/Species/Sample/Dilution | Reference |
|---|---|
| |
Eagleson K, Pimenta A, Burns M, Fairfull L, Cornuet P, Zhang L, et al. Distinct domains of the limbic system-associated membrane protein (LAMP) mediate discrete effects on neurite outgrowth. Mol Cell Neurosci. 2003;24:725-40 pubmed
| |
Gil O, Zhang L, Chen S, Ren Y, Pimenta A, Zanazzi G, et al. Complementary expression and heterophilic interactions between IgLON family members neurotrimin and LAMP. J Neurobiol. 2002;51:190-204 pubmed
| |
Mann F, Zhukareva V, Pimenta A, Levitt P, Bolz J. Membrane-associated molecules guide limbic and nonlimbic thalamocortical projections. J Neurosci. 1998;18:9409-19 pubmed
| |
Côté P, Levitt P, Parent A. Limbic system-associated membrane protein (LAMP) in primate amygdala and hippocampus. Hippocampus. 1996;6:483-94 pubmed
| |
Côté P, Levitt P, Parent A. Distribution of limbic system-associated membrane protein immunoreactivity in primate basal ganglia. Neuroscience. 1995;69:71-81 pubmed
| |
Zhukareva V, Levitt P. The limbic system-associated membrane protein (LAMP) selectively mediates interactions with specific central neuron populations. Development. 1995;121:1161-72 pubmed
| |
Pimenta A, Zhukareva V, Barbe M, Reinoso B, Grimley C, Henzel W, et al. The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting. Neuron. 1995;15:287-97 pubmed
| |
Levitt P. A monoclonal antibody to limbic system neurons. Science. 1984;223:299-301 pubmed
| |
Horton H, Levitt P. Developmental studies with a specific cell surface marker for limbic system neurons. Prog Clin Biol Res. 1986;217A:111-3 pubmed
| |
Horton H, Levitt P. A unique membrane protein is expressed on early developing limbic system axons and cortical targets. J Neurosci. 1988;8:4653-61 pubmed
| |
Keller F, Levitt P. Developmental and regeneration-associated regulation of the limbic system associated membrane protein in explant cultures of the rat brain. Neuroscience. 1989;28:455-74 pubmed
| |
Keller F, Rimvall K, Barbe M, Levitt P. A membrane glycoprotein associated with the limbic system mediates the formation of the septo-hippocampal pathway in vitro. Neuron. 1989;3:551-61 pubmed
| |
Zacco A, Cooper V, Chantler P, Fisher Hyland S, Horton H, Levitt P. Isolation, biochemical characterization and ultrastructural analysis of the limbic system-associated membrane protein (LAMP), a protein expressed by neurons comprising functional neural circuits. J Neurosci. 1990;10:73-90 pubmed
| |
Chesselet M, Gonzales C, Levitt P. Heterogeneous distribution of the limbic system-associated membrane protein in the caudate nucleus and substantia nigra of the cat. Neuroscience. 1991;40:725-33 pubmed
|
product information
Internal ID :
4316
Name :
2G9
Depositor Name :
Levitt, P.R.
Depositor Institution :
Vanderbilt Kennedy Ctr. for Research on Human Development
Date Deposited :
1/23/08
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
Lsamp (Lamp)
Antigen Species :
Rat
Host Species :
mouse
Isotype :
MIgG2a
Isotype for catalog (legacy) :
IgG2a
Positive Tested Species Reactivity :
Bovine,Cat,Fish,Human,Mouse,Primate,Rat
Species Tested (legacy) :
cross reacts with rat, mouse, cat, primate (including human), fish, cow
Initial Publication Pubmed ID :
6199842
Collections :
CD antigens,Cell adhesion,Cell signaling,Human,Neurodevelopment
Search Keywords :
Levitt, P.R., Lsamp (Lamp), Rat, MIgG2a, Rat/Human/Mouse/Cat/Primate/Fish/Bovine, Lsamp, Lamp, AB_2138210, monoclonal, Human/Cell signaling/Cluster Determinant antigens/Cell adhesion/Neurodevelopment, Function Blocking/Immunoprecipitation/Western Blot/Immunofluorescence/Immunohistochemistry
Antigen Molecular Weight :
Predicted: 32 kDa (mature form); Apparent: 64-68 kDa
Gene :
Lsamp
Alternate Gene Name(s) :
Lamp
Uniprot ID :
Q62813
Antibody Registry ID :
AB_2138210
Immunogen :
Adult Rat hippocampal crude membrane preparation
Immunogen Sequence :
Full length protein
Clonality :
Monoclonal
Myeloma Strain :
NS-1
Epitope Mapped :
Yes
Epitope Location or Sequence :
First Ig domain (aa 1-94 of mature protein)
Epitope Map PubMed ID :
14664821
Recommended Applications :
Function Blocking,Immunofluorescence,Immunohistochemistry,Immunoprecipitation,Western Blot
Immunoblotting (legacy) :
Yes
Immunohistochemistry Pubmed IDs :
3199199 2922110 1688937 1676494 8953302
Immunofluorescence Pubmed IDs :
6199842 3199199 1688937 7646886 7743928 8637634 8953302 11984841
Western Blot Pubmed IDs :
3199199 1688937 7646886 7743928 14664821
Immunoprecipitation Pubmed IDs :
1688937 7646886 7743928
Function Blocking Pubmed IDs :
2642010 7646886 7743928 9801379 14664821
Pubmed IDs :
3749116
Additional Information :
Lsamp is a GPI-anchored glycoprotein.
DSHB Growth Medium :
Iscove's
References (legacy) :
Prog. Clin. Biol. Res. 217A, 111-113.; J. Neurosci. 8, 4653-4661.; Neuron 3, 551-561.; Neuroscience 28, 455-474.; J Neurosci. 10, 73-90.; Neuroscience 40, 725-733.; Neuron 15, 287-297.; Development 121, 1161-1172.; Neuroscience 69, 71-81.; Hippocampus 6, 483-494.; J. Comp. Neurol. 375, 274-288.; J. Comp. Neurol. 375, 289-302.; Mol. Cell. Neurosci. 10, 43-55.; J. Neurosci. 18, 9409-9419.; J. Neurobiol. 51, 190-204.; Mol. Cell. Neurosci. 24, 725-740.
more info or order :
company information
Developmental Studies Hybridoma Bank
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