product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
futsch
catalog :
22C10
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
22C10
reactivity :
Drosophila melanogaster
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
citations: 120
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; Drosophila melanogaster; loading ...; fig 3a
Kim Y, Cho K. POU domain motif3 (Pdm3) induces wingless (wg) transcription and is essential for development of larval neuromuscular junctions in Drosophila. Sci Rep. 2020;10:517 pubmed publisher
  • immunohistochemistry; Drosophila melanogaster; 1:2; fig 7k
Hanlon C, Andrew D. Drosophila FoxL1 non-autonomously coordinates organ placement during embryonic development. Dev Biol. 2016;419:273-284 pubmed publisher
  • immunohistochemistry - frozen section; Drosophila melanogaster; 1:100; fig 2
Li T, Giagtzoglou N, Eberl D, Jaiswal S, Cai T, Godt D, et al. The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. elife. 2016;5: pubmed publisher
  • immunohistochemistry; Drosophila melanogaster; 1:50; fig 2t
Gresser A, Gutzwiller L, Gauck M, Hartenstein V, Cook T, Gebelein B. Rhomboid Enhancer Activity Defines a Subset of Drosophila Neural Precursors Required for Proper Feeding, Growth and Viability. PLoS ONE. 2015;10:e0134915 pubmed publisher
  • immunocytochemistry; Drosophila melanogaster; 1:200; fig s5
Kanamori T, Yoshino J, Yasunaga K, Dairyo Y, Emoto K. Local endocytosis triggers dendritic thinning and pruning in Drosophila sensory neurons. Nat Commun. 2015;6:6515 pubmed publisher
Lapart J, Gottardo M, Cortier E, Duteyrat J, Augière C, Mangé A, et al. Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila. elife. 2019;8: pubmed publisher
Ramaekers A, Claeys A, Kapun M, Mouchel Vielh E, Potier D, Weinberger S, et al. Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs. Dev Cell. 2019;50:780-792.e7 pubmed publisher
Donde A, Sun M, Ling J, Braunstein K, Pang B, Wen X, et al. Splicing repression is a major function of TDP-43 in motor neurons. Acta Neuropathol. 2019;: pubmed publisher
Trostnikov M, Roshina N, Boldyrev S, Veselkina E, Zhuikov A, Krementsova A, et al. Disordered Expression of shaggy, the Drosophila Gene Encoding a Serine-Threonine Protein Kinase GSK3, Affects the Lifespan in a Transcript-, Stage-, and Tissue-Specific Manner. Int J Mol Sci. 2019;20: pubmed publisher
Wang Y, Rui M, Tang Q, Bu S, Yu F. Patronin governs minus-end-out orientation of dendritic microtubules to promote dendrite pruning in Drosophila. elife. 2019;8: pubmed publisher
Nakato E, Liu X, Eriksson I, Yamamoto M, Kinoshita Toyoda A, Toyoda H, et al. Establishment and characterization of Drosophila cell lines mutant for heparan sulfate modifying enzymes. Glycobiology. 2019;29:479-489 pubmed publisher
Kim N, Kim S, Nahm M, Kopke D, Kim J, Cho E, et al. BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis. Nat Commun. 2019;10:684 pubmed publisher
Schor I, Bussotti G, Males M, Forneris M, Viales R, Enright A, et al. Non-coding RNA Expression, Function, and Variation during Drosophila Embryogenesis. Curr Biol. 2018;28:3547-3561.e9 pubmed publisher
Barber K, Hruska M, Bush K, Martinez J, Fei H, Levitan I, et al. Levels of Par-1 kinase determine the localization of Bruchpilot at the Drosophila neuromuscular junction synapses. Sci Rep. 2018;8:16099 pubmed publisher
Huang Y, Huang S, Di Scala C, Wang Q, Wandall H, Fantini J, et al. The glycosphingolipid MacCer promotes synaptic bouton formation in Drosophila by interacting with Wnt. elife. 2018;7: pubmed publisher
Hakes A, Otsuki L, Brand A. A newly discovered neural stem cell population is generated by the optic lobe neuroepithelium during embryogenesis in Drosophila melanogaster. Development. 2018;145: pubmed publisher
Koon A, Chen Z, Peng S, Fung J, Zhang X, Lembke K, et al. Drosophila Exo70 Is Essential for Neurite Extension and Survival under Thermal Stress. J Neurosci. 2018;38:8071-8086 pubmed publisher
Nithianandam V, Chien C. Actin blobs prefigure dendrite branching sites. J Cell Biol. 2018;217:3731-3746 pubmed publisher
Drelon C, Belálcazar H, Secombe J. The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila. Genetics. 2018;209:773-787 pubmed publisher
Zur Lage P, Stefanopoulou P, Styczynska Soczka K, Quinn N, Mali G, von Kriegsheim A, et al. Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP. J Cell Biol. 2018;217:2583-2598 pubmed publisher
Gaburro J, Bhatti A, Harper J, Jeanne I, Dearnley M, Green D, et al. Neurotropism and behavioral changes associated with Zika infection in the vector Aedes aegypti. Emerg Microbes Infect. 2018;7:68 pubmed publisher
KAVALER J, Duan H, Aradhya R, de Navas L, Joseph B, Shklyar B, et al. miRNA suppression of a Notch repressor directs non-neuronal fate in Drosophila mechanosensory organs. J Cell Biol. 2018;217:571-583 pubmed publisher
Coutinho Budd J, Sheehan A, Freeman M. The secreted neurotrophin Spätzle 3 promotes glial morphogenesis and supports neuronal survival and function. Genes Dev. 2017;31:2023-2038 pubmed publisher
Jenkins B, Saunders H, Record H, Johnson Schlitz D, Wildonger J. Effects of mutating ?-tubulin lysine 40 on sensory dendrite development. J Cell Sci. 2017;130:4120-4131 pubmed publisher
Tenenbaum C, Misra M, Alizzi R, Gavis E. Enclosure of Dendrites by Epidermal Cells Restricts Branching and Permits Coordinated Development of Spatially Overlapping Sensory Neurons. Cell Rep. 2017;20:3043-3056 pubmed publisher
Poe A, Tang L, Wang B, Li Y, Sapar M, Han C. Dendritic space-filling requires a neuronal type-specific extracellular permissive signal in Drosophila. Proc Natl Acad Sci U S A. 2017;114:E8062-E8071 pubmed publisher
Vishal K, Brooks D, Bawa S, Gameros S, Stetsiv M, Geisbrecht E. Adult Muscle Formation Requires Drosophila Moleskin for Proliferation of Wing Disc-Associated Muscle Precursors. Genetics. 2017;206:199-213 pubmed publisher
Shukla J, Deshpande G, Shashidhara L. Ataxin 2-binding protein 1 is a context-specific positive regulator of Notch signaling during neurogenesis in Drosophila melanogaster. Development. 2017;144:905-915 pubmed publisher
Kremer M, Jung C, Batelli S, Rubin G, Gaul U. The glia of the adult Drosophila nervous system. Glia. 2017;65:606-638 pubmed publisher
Wang M, Chen P, Wang C, Lai T, Tsai P, Cheng Y, et al. Dbo/Henji Modulates Synaptic dPAK to Gate Glutamate Receptor Abundance and Postsynaptic Response. PLoS Genet. 2016;12:e1006362 pubmed publisher
Vieillard J, Paschaki M, Duteyrat J, Augière C, Cortier E, Lapart J, et al. Transition zone assembly and its contribution to axoneme formation in Drosophila male germ cells. J Cell Biol. 2016;214:875-89 pubmed publisher
Sears J, Broihier H. FoxO regulates microtubule dynamics and polarity to promote dendrite branching in Drosophila sensory neurons. Dev Biol. 2016;418:40-54 pubmed publisher
McLaughlin C, Nechipurenko I, Liu N, Broihier H. A Toll receptor-FoxO pathway represses Pavarotti/MKLP1 to promote microtubule dynamics in motoneurons. J Cell Biol. 2016;214:459-74 pubmed publisher
Karak S, Jacobs J, Kittelmann M, Spalthoff C, Katana R, Sivan Loukianova E, et al. Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing. Sci Rep. 2015;5:17085 pubmed publisher
Chen J, Kao L, Jana S, Sivan Loukianova E, Mendonça S, Cabrera O, et al. Rootletin organizes the ciliary rootlet to achieve neuron sensory function in Drosophila. J Cell Biol. 2015;211:435-53 pubmed publisher
Meserve J, Duronio R. Scalloped and Yorkie are required for cell cycle re-entry of quiescent cells after tissue damage. Development. 2015;142:2740-51 pubmed publisher
Yu Q, Li X, Liu C, Cui W, Mu Z, Zhao X, et al. Evolutionarily conserved repulsive guidance role of slit in the silkworm Bombyx mori. PLoS ONE. 2014;9:e109377 pubmed publisher
Caine C, Kasherov P, Silber J, Lalouette A. Mef2 interacts with the Notch pathway during adult muscle development in Drosophila melanogaster. PLoS ONE. 2014;9:e108149 pubmed publisher
Lüchtenborg A, Solis G, Egger Adam D, Koval A, Lin C, Blanchard M, et al. Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeleton. Development. 2014;141:3399-409 pubmed publisher
Romano G, Klima R, Buratti E, Verstreken P, Baralle F, Feiguin F. Chronological requirements of TDP-43 function in synaptic organization and locomotive control. Neurobiol Dis. 2014;71:95-109 pubmed publisher
Copf T. Developmental shaping of dendritic arbors in Drosophila relies on tightly regulated intra-neuronal activity of protein kinase A (PKA). Dev Biol. 2014;393:282-297 pubmed publisher
Ciglar L, Girardot C, Wilczynski B, Braun M, Furlong E. Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis. Development. 2014;141:2633-43 pubmed publisher
Iacobucci G, Rahman N, Valtueña A, Nayak T, Gunawardena S. Spatial and temporal characteristics of normal and perturbed vesicle transport. PLoS ONE. 2014;9:e97237 pubmed publisher
Lepicard S, Franco B, de Bock F, Parmentier M. A presynaptic role of microtubule-associated protein 1/Futsch in Drosophila: regulation of active zone number and neurotransmitter release. J Neurosci. 2014;34:6759-71 pubmed publisher
Nguyen M, McCracken C, Milner E, Goetschius D, Weiner A, Long M, et al. ?-tubulin controls neuronal microtubule polarity independently of Golgi outposts. Mol Biol Cell. 2014;25:2039-50 pubmed publisher
Anderson A, Weasner B, Weasner B, Kumar J. The Drosophila Wilms׳ Tumor 1-Associating Protein (WTAP) homolog is required for eye development. Dev Biol. 2014;390:170-80 pubmed publisher
Tevy M, Seyres D, Traina C, Perrin L, Capovilla M. Ndae1 expression and regulation in Drosophila embryos. PLoS ONE. 2014;9:e92956 pubmed publisher
Mao C, Xiong Y, Xiong Z, Wang Q, Zhang Y, Jin S. Microtubule-severing protein Katanin regulates neuromuscular junction development and dendritic elaboration in Drosophila. Development. 2014;141:1064-74 pubmed publisher
Romano M, Buratti E, Romano G, Klima R, Del Bel Belluz L, Stuani C, et al. Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43). J Biol Chem. 2014;289:7121-30 pubmed publisher
Ferreira T, Ou Y, Li S, Giniger E, van Meyel D. Dendrite architecture organized by transcriptional control of the F-actin nucleator Spire. Development. 2014;141:650-60 pubmed publisher
Linneweber G, Jacobson J, Busch K, Hudry B, Christov C, Dormann D, et al. Neuronal control of metabolism through nutrient-dependent modulation of tracheal branching. Cell. 2014;156:69-83 pubmed publisher
Sanhueza M, Zechini L, Gillespie T, Pennetta G. Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles. Biol Open. 2014;3:59-71 pubmed publisher
Moran M, Tare M, Kango Singh M, Singh A. Homeotic Gene teashirt (tsh) has a neuroprotective function in amyloid-beta 42 mediated neurodegeneration. PLoS ONE. 2013;8:e80829 pubmed publisher
Martin J, Chong T, Ferree P. Male killing Spiroplasma preferentially disrupts neural development in the Drosophila melanogaster embryo. PLoS ONE. 2013;8:e79368 pubmed publisher
Park J, Lee J, Shim J, Han W, Lee J, Bae Y, et al. dTULP, the Drosophila melanogaster homolog of tubby, regulates transient receptor potential channel localization in cilia. PLoS Genet. 2013;9:e1003814 pubmed publisher
Jerber J, Baas D, Soulavie F, Chhin B, Cortier E, Vesque C, et al. The coiled-coil domain containing protein CCDC151 is required for the function of IFT-dependent motile cilia in animals. Hum Mol Genet. 2014;23:563-77 pubmed publisher
von Hilchen C, Bustos A, Giangrande A, Technau G, Altenhein B. Predetermined embryonic glial cells form the distinct glial sheaths of the Drosophila peripheral nervous system. Development. 2013;140:3657-68 pubmed publisher
Duncan J, Lytle N, Zuniga A, Goldstein L. The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS ONE. 2013;8:e68324 pubmed publisher
Bjorum S, Simonette R, Alanis R, Wang J, Lewis B, Trejo M, et al. The Drosophila BTB domain protein Jim Lovell has roles in multiple larval and adult behaviors. PLoS ONE. 2013;8:e61270 pubmed publisher
Upadhyay A, Kandachar V, Zitserman D, Tong X, Roegiers F. Sanpodo controls sensory organ precursor fate by directing Notch trafficking and binding γ-secretase. J Cell Biol. 2013;201:439-48 pubmed publisher
Hopkins P. Neurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding protein. PLoS ONE. 2013;8:e55810 pubmed publisher
Kamimura K, Ueno K, Nakagawa J, Hamada R, Saitoe M, Maeda N. Perlecan regulates bidirectional Wnt signaling at the Drosophila neuromuscular junction. J Cell Biol. 2013;200:219-33 pubmed publisher
Mellert D, ROBINETT C, Baker B. doublesex functions early and late in gustatory sense organ development. PLoS ONE. 2012;7:e51489 pubmed publisher
Tsai P, Wang M, Kao H, Cheng Y, Walker J, Chen R, et al. Neurofibromin mediates FAK signaling in confining synapse growth at Drosophila neuromuscular junctions. J Neurosci. 2012;32:16971-81 pubmed publisher
Bolkan B, Triphan T, Kretzschmar D. β-secretase cleavage of the fly amyloid precursor protein is required for glial survival. J Neurosci. 2012;32:16181-92 pubmed publisher
Bhattacharya A, Baker N. The role of the bHLH protein hairy in morphogenetic furrow progression in the developing Drosophila eye. PLoS ONE. 2012;7:e47503 pubmed publisher
Prieto Godino L, Diegelmann S, Bate M. Embryonic origin of olfactory circuitry in Drosophila: contact and activity-mediated interactions pattern connectivity in the antennal lobe. PLoS Biol. 2012;10:e1001400 pubmed publisher
Rovani M, Brachmann C, Ramsay G, Katzen A. The dREAM/Myb-MuvB complex and Grim are key regulators of the programmed death of neural precursor cells at the Drosophila posterior wing margin. Dev Biol. 2012;372:88-102 pubmed publisher
Slováková J, Speicher S, Sanchez Soriano N, Prokop A, Carmena A. The actin-binding protein Canoe/AF-6 forms a complex with Robo and is required for Slit-Robo signaling during axon pathfinding at the CNS midline. J Neurosci. 2012;32:10035-44 pubmed publisher
Boulanger A, Farge M, Ramanoudjame C, Wharton K, Dura J. Drosophila motor neuron retraction during metamorphosis is mediated by inputs from TGF-?/BMP signaling and orphan nuclear receptors. PLoS ONE. 2012;7:e40255 pubmed publisher
Sun K, Westholm J, Tsurudome K, Hagen J, Lu Y, Kohwi M, et al. Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants. PLoS Genet. 2012;8:e1002515 pubmed publisher
Nechipurenko I, Broihier H. FoxO limits microtubule stability and is itself negatively regulated by microtubule disruption. J Cell Biol. 2012;196:345-62 pubmed publisher
Nguyen M, Stone M, Rolls M. Microtubules are organized independently of the centrosome in Drosophila neurons. Neural Dev. 2011;6:38 pubmed publisher
Coffee R, Williamson A, Adkins C, Gray M, Page T, Broadie K. In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. Hum Mol Genet. 2012;21:900-15 pubmed publisher
Graf E, Heerssen H, Wright C, Davis G, DiAntonio A. Stathmin is required for stability of the Drosophila neuromuscular junction. J Neurosci. 2011;31:15026-34 pubmed publisher
Voelzmann A, Bauer R. Embryonic expression of Drosophila ceramide synthase schlank in developing gut, CNS and PNS. Gene Expr Patterns. 2011;11:501-10 pubmed publisher
Henthorn K, Roux M, Herrera C, Goldstein L. A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell. 2011;22:4038-46 pubmed publisher
Reinecke J, DeVos S, McGrath J, Shepard A, Goncharoff D, Tait D, et al. Implicating calpain in tau-mediated toxicity in vivo. PLoS ONE. 2011;6:e23865 pubmed publisher
Zheng L, Michelson Y, Freger V, Avraham Z, Venken K, Bellen H, et al. Drosophila Ten-m and filamin affect motor neuron growth cone guidance. PLoS ONE. 2011;6:e22956 pubmed publisher
Sprecher S, Cardona A, Hartenstein V. The Drosophila larval visual system: high-resolution analysis of a simple visual neuropil. Dev Biol. 2011;358:33-43 pubmed publisher
Yamasaki Y, Lim Y, Niwa N, Hayashi S, Tsuda L. Robust specification of sensory neurons by dual functions of charlatan, a Drosophila NRSF/REST-like repressor of extramacrochaetae and hairy. Genes Cells. 2011;16:896-909 pubmed publisher
Neufeld S, Hibbert A, Chen B. Opposing roles of PlexinA and PlexinB in axonal branch and varicosity formation. Mol Brain. 2011;4:15 pubmed publisher
Barry K, Abed M, Kenyagin D, Werwie T, Boico O, Orian A, et al. The Drosophila STUbL protein Degringolade limits HES functions during embryogenesis. Development. 2011;138:1759-69 pubmed publisher
Besson M, Sinakevitch I, Melon C, Iché Torres M, Birman S. Involvement of the Drosophila taurine/aspartate transporter dEAAT2 in selective olfactory and gustatory perceptions. J Comp Neurol. 2011;519:2734-57 pubmed publisher
Momota R, Naito I, Ninomiya Y, Ohtsuka A. Drosophila type XV/XVIII collagen, Mp, is involved in Wingless distribution. Matrix Biol. 2011;30:258-66 pubmed publisher
Godena V, Romano G, Romano M, Appocher C, Klima R, Buratti E, et al. TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization. PLoS ONE. 2011;6:e17808 pubmed publisher
Chu LaGraff Q, Blanchette C, O Hern P, Denefrio C. The Batten disease Palmitoyl Protein Thioesterase 1 gene regulates neural specification and axon connectivity during Drosophila embryonic development. PLoS ONE. 2010;5:e14402 pubmed publisher
Koon A, Ashley J, Barria R, Dasgupta S, Brain R, Waddell S, et al. Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling. Nat Neurosci. 2011;14:190-9 pubmed publisher
Yao A, Jin S, Li X, Liu Z, Ma X, Tang J, et al. Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria. Hum Mol Genet. 2011;20:51-63 pubmed publisher
Silies M, Klämbt C. APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS. Nat Neurosci. 2010;13:1357-64 pubmed publisher
Lin C, Tsai P, Wu R, Chien C. LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3ß. J Neurosci. 2010;30:13138-49 pubmed publisher
Nagai R, Hashimoto R, Yamaguchi M. Drosophila Syntrophins are involved in locomotion and regulation of synaptic morphology. Exp Cell Res. 2010;316:2313-21 pubmed
Lee J, Moon S, Cha Y, Chung Y. Drosophila TRPN(=NOMPC) channel localizes to the distal end of mechanosensory cilia. PLoS ONE. 2010;5:e11012 pubmed publisher
Boerner J, Duch C. Average shape standard atlas for the adult Drosophila ventral nerve cord. J Comp Neurol. 2010;518:2437-55 pubmed publisher
Higashi Kovtun M, Mosca T, Dickman D, Meinertzhagen I, Schwarz T. Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction. J Neurosci. 2010;30:5253-68 pubmed publisher
Guruharsha K, Ruiz Gomez M, Ranganath H, Siddharthan R, Vijayraghavan K. The complex spatio-temporal regulation of the Drosophila myoblast attractant gene duf/kirre. PLoS ONE. 2009;4:e6960 pubmed publisher
Fabre C, Casal J, Lawrence P. The abdomen of Drosophila: does planar cell polarity orient the neurons of mechanosensory bristles?. Neural Dev. 2008;3:12 pubmed
Besse F, Mertel S, Kittel R, Wichmann C, Rasse T, Sigrist S, et al. The Ig cell adhesion molecule Basigin controls compartmentalization and vesicle release at Drosophila melanogaster synapses. J Cell Biol. 2007;177:843-55 pubmed
Beramendi A, Peron S, Casanova G, Reggiani C, Cantera R. Neuromuscular junction in abdominal muscles of Drosophila melanogaster during adulthood and aging. J Comp Neurol. 2007;501:498-508 pubmed
Wang X, Shaw W, Tsang H, Reid E, O Kane C. Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules. Nat Neurosci. 2007;10:177-85 pubmed
Holohan E, zur Lage P, Jarman A. Multiple enhancers contribute to spatial but not temporal complexity in the expression of the proneural gene, amos. BMC Dev Biol. 2006;6:53 pubmed
Kim M, Jan L, Jan Y. The bHLH-PAS protein Spineless is necessary for the diversification of dendrite morphology of Drosophila dendritic arborization neurons. Genes Dev. 2006;20:2806-19 pubmed
Gögel S, Wakefield S, Tear G, Klämbt C, Gordon Weeks P. The Drosophila microtubule associated protein Futsch is phosphorylated by Shaggy/Zeste-white 3 at an homologous GSK3beta phosphorylation site in MAP1B. Mol Cell Neurosci. 2006;33:188-99 pubmed
Dutta D, Shaw S, Maqbool T, Pandya H, Vijayraghavan K. Drosophila Heartless acts with Heartbroken/Dof in muscle founder differentiation. PLoS Biol. 2005;3:e337 pubmed
Melcher C, Pankratz M. Candidate gustatory interneurons modulating feeding behavior in the Drosophila brain. PLoS Biol. 2005;3:e305 pubmed
Sherwood N, Sun Q, Xue M, Zhang B, Zinn K. Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. PLoS Biol. 2004;2:e429 pubmed
Michaud S, Tanguay R. Expression of the Hsp23 chaperone during Drosophila embryogenesis: association to distinct neural and glial lineages. BMC Dev Biol. 2003;3:9 pubmed
Robb S, SANCHEZ ALVARADO A. Identification of immunological reagents for use in the study of freshwater planarians by means of whole-mount immunofluorescence and confocal microscopy. Genesis. 2002;32:293-8 pubmed
Rusten T, Cantera R, Urban J, Technau G, Kafatos F, Barrio R. Spalt modifies EGFR-mediated induction of chordotonal precursors in the embryonic PNS of Drosophila promoting the development of oenocytes. Development. 2001;128:711-22 pubmed
Ben Yaacov S, Le Borgne R, Abramson I, Schweisguth F, Schejter E. Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J Cell Biol. 2001;152:1-13 pubmed
Roos J, Hummel T, Ng N, Klämbt C, Davis G. Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron. 2000;26:371-82 pubmed
Hummel T, Krukkert K, Roos J, Davis G, Klämbt C. Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development. Neuron. 2000;26:357-70 pubmed
Hoyle H, Turner F, Raff E. A transient specialization of the microtubule cytoskeleton is required for differentiation of the Drosophila visual system. Dev Biol. 2000;221:375-89 pubmed
Cremazy F, Berta P, Girard F. Sox neuro, a new Drosophila Sox gene expressed in the developing central nervous system. Mech Dev. 2000;93:215-9 pubmed
Kavaler J, Fu W, Duan H, Noll M, Posakony J. An essential role for the Drosophila Pax2 homolog in the differentiation of adult sensory organs. Development. 1999;126:2261-72 pubmed
Estes P, Roos J, van der Bliek A, Kelly R, Krishnan K, Ramaswami M. Traffic of dynamin within individual Drosophila synaptic boutons relative to compartment-specific markers. J Neurosci. 1996;16:5443-56 pubmed
Bonini N, Leiserson W, Benzer S. The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell. 1993;72:379-95 pubmed
Fujita S, Zipursky S, Benzer S, Ferrus A, Shotwell S. Monoclonal antibodies against the Drosophila nervous system. Proc Natl Acad Sci U S A. 1982;79:7929-33 pubmed
Zipursky S, Venkatesh T, Teplow D, Benzer S. Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes. Cell. 1984;36:15-26 pubmed
Van Vactor D, Krantz D, Reinke R, Zipursky S. Analysis of mutants in chaoptin, a photoreceptor cell-specific glycoprotein in Drosophila, reveals its role in cellular morphogenesis. Cell. 1988;52:281-90 pubmed
product information
Internal ID :
779
Name :
22C10
Depositor Name :
Benzer, S. / Colley, N.
Depositor Institution :
California Institute of Technology
Date Deposited :
3/27/98
Allow Hybridoma Distribution :
Yes
Cells Available (legacy) :
Yes
Antigen :
futsch
Antigen Species :
Drosophila
Host Species :
mouse
Isotype :
MIgG1, kappa light chain
Isotype for catalog (legacy) :
IgG1, kappa light chain
Positive Tested Species Reactivity :
Drosophila,Insect,Mosquito,Planaria
Species Tested (legacy) :
Drosophila and planaria
Initial Publication Pubmed ID :
6818557 6420071
Depositor Notes (Special Instructions) :
Blots well using 4% SDS-PAGE
Collections :
Drosophila antigens,Neurodevelopment
Search Keywords :
Benzer, neurons, mouse, futsch, AB_528403, MIgG1, kappa light chain, Monoclonal, Drosophila, Planaria, Insect, 22C10; 22C20; CG14772; CG3064; CG34387; Dmel CG34387; EG:49E4.1; Futch; Futsch; lincRNA.936; Mab 22C10; mAb-22C10; mAb22c10; Map-1B; MAP-IB; map1b; MAP1B; olk; ssC10, Immunofluorescence,Immunohistochemistry,Western Blot
Antigen Molecular Weight :
Predicted: 575 kDa, Apparent: >500kDa
Gene :
futsch
Alternate Gene Name(s) :
22C10/FUTSCH; 22C20; CG14772; CG3064; CG34387; Dmel CG34387; EG:49E4.1; Futch; Futsch; lincRNA.936; Mab 22C10; mAb-22C10; mAb22c10; Map-1B; MAP-IB; Map1B; Olk; ssC10
Uniprot ID :
B4R2P4
Antibody Registry ID :
AB_528403
Immunogen :
adult fly heads homogenates
Clonality :
Monoclonal
Myeloma Strain :
NS-1
Epitope Mapped :
Yes
Epitope Location or Sequence :
aa 2517 to 2758 of futsch
Epitope Map PubMed ID :
16949836 10839355
Recommended Applications :
Immunofluorescence,Immunohistochemistry,Western Blot
Immunoblotting (legacy) :
yes 4% PAGE
Immunohistochemistry Pubmed IDs :
16949836 10839355 24828631 24961800 8757257 10839356 24449841 24550114 25088713 24690230 24492607 25017992 24067530 23609534 23152602 24282556 23240029 22960039 22815517 23118874 22347817 21412434 20881132 21186359 20935173 21486924 21907829 20890296 20632467 22080836 20392948 22016536 8431945 10207150 10790333 10781960 11171396 17220882 21477650 23840848 20543979 21762412 21781960 6420071 17015425
Immunofluorescence Pubmed IDs :
16949836 25247309 23175848 23055825 23609534 23152602 23240029 22960039 22815517 23118874 22347817 21412434 20935173 21486924 21907829 20890296 20392948 10781960 20543979 21762412 25139856 11948917 17220882 30382129 30393032 27736876 28249984 28874572 29691362 30869121 31332509
Western Blot Pubmed IDs :
16949836 10839355 21486924 2449286
Pubmed IDs :
25139856
Depositor Growth Medium :
15% fetal bovine serum in RPMI 1640 with 1x pen/strep
Additional Information :
RRID: AB_528403
DSHB Growth Medium :
RPMI
References (legacy) :
Proc. Natl. Acad. Sci. USA 79, 7929-7933.; Cell 36, 15-26.; Cell 72, 379-395.; Development 126, 2261-2272.; Dev. Biol. 221, 375-389.; Mech. Dev. 93, 215-219.; Dev. Biol. 221, 375-389.; Neuron 26, 357-370.; Development 128, 711-722.; Genesis 32, 293-298.; Nat. Neurosci. 10(2), 177-185.; Matrix Biol. 30, 258-266.; PLoS ONE 8(6), e68324. Doi:10.1371/journal.pone.0068324.; Development 141, 3399-3409.
company information
Developmental Studies Hybridoma Bank
University of Iowa
http://dshb.biology.uiowa.edu
headquarters: US