| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig s2c
- immunocytochemistry; mouse; loading ...; fig 5b
| Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 1c
- western blot; mouse; loading ...; fig 1d
| Massa L pez D, Thelen M, Stahl F, Thiel C, Linhorst A, Sylvester M, et al. The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP. elife. 2019;8: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7s1d
| Traub L. A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation. elife. 2019;8: pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 5c
- western blot; mouse; 1:500; loading ...; fig 5a
| Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed publisher |
- western blot; mouse; 1:200; loading ...; fig 7c
| Götzl J, Colombo A, Fellerer K, Reifschneider A, Werner G, Tahirovic S, et al. Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice. Mol Neurodegener. 2018;13:48 pubmed publisher |
- immunohistochemistry; mouse; 1:250; loading ...; fig 3g
- immunocytochemistry; human; 1:1000; loading ...; fig 2b
| Pajares M, Rojo A, Arias E, Díaz Carretero A, Cuervo A, Cuadrado A. Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A. Autophagy. 2018;14:1310-1322 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 5i
| Hartlova A, Herbst S, Peltier J, Rodgers A, Bilkei Gorzo O, Fearns A, et al. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. EMBO J. 2018;37: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 4c
| Chiang A, Fowler S, Savjani R, Hilsenbeck S, Wallace C, Cirrito J, et al. Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice. J Exp Med. 2018;215:1349-1364 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig s3d
| Ho T, Warr M, Adelman E, Lansinger O, Flach J, Verovskaya E, et al. Autophagy maintains the metabolism and function of young and old stem cells. Nature. 2017;543:205-210 pubmed publisher |
- western blot; mouse; loading ...; tbl 1
| Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 2a
- western blot; mouse; loading ...; fig 2b
| Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 7
| Skurat A, Segvich D, DePaoli Roach A, Roach P. Novel method for detection of glycogen in cells. Glycobiology. 2017;27:416-424 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 3e
- western blot; mouse; 1:200; loading ...; fig s4e
- immunocytochemistry; human; 1:100; loading ...; fig 5a
| Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed publisher |
- immunohistochemistry - frozen section; mouse; loading ...; fig s7o
| Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2017;541:228-232 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 3a
| Rofe A, Davis L, Whittingham J, Latimer Bowman E, Wilkinson A, Pryor P. The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis. Microbiologyopen. 2017;6: pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 5d
| Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5f
| Hubbs A, Fluharty K, Edwards R, Barnabei J, Grantham J, Palmer S, et al. Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity. Am J Pathol. 2016;186:2887-2908 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig 4c
- western blot; mouse; 1:250; loading ...; fig 1f
| Wolf H, Damme M, Stroobants S, D Hooge R, Beck H, Hermans Borgmeyer I, et al. A mouse model for fucosidosis recapitulates storage pathology and neurological features of the milder form of the human disease. Dis Model Mech. 2016;9:1015-28 pubmed publisher |
- immunocytochemistry; mouse; fig 2m
| Dennis M, Delevoye C, Acosta Ruiz A, Hurbain I, Romao M, Hesketh G, et al. BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers. J Cell Biol. 2016;214:293-308 pubmed publisher |
- western blot; mouse; fig 6
| Wang H, Wang R, Carrera I, Xu S, Lakshmana M. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. Eneuro. 2016;3: pubmed publisher |
- immunocytochemistry; mouse; fig 2
| Pastore N, Brady O, Diab H, Martina J, Sun L, Huynh T, et al. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016;12:1240-58 pubmed publisher |
- immunocytochemistry; mouse; loading ...; fig 2
- immunocytochemistry; human; loading ...; fig 8a
| Jiang H, Zhang X, Lin H. Lysine fatty acylation promotes lysosomal targeting of TNF-?. Sci Rep. 2016;6:24371 pubmed publisher |
- immunocytochemistry; mouse; fig s5
| Brahic M, Bousset L, Bieri G, Melki R, Gitler A. Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1. Acta Neuropathol. 2016;131:539-48 pubmed publisher |
- immunohistochemistry; mouse; fig 2
| Yuan P, Grutzendler J. Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity. J Neurosci. 2016;36:632-41 pubmed publisher |
- immunocytochemistry; mouse; 1:2000; fig 7
| Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed publisher |
- western blot; human; fig 2
| Vural A, Al Khodor S, Cheung G, Shi C, Srinivasan L, McQuiston T, et al. Activator of G-Protein Signaling 3-Induced Lysosomal Biogenesis Limits Macrophage Intracellular Bacterial Infection. J Immunol. 2016;196:846-56 pubmed publisher |
- immunohistochemistry; mouse
| Sun L, Hua Y, Vergarajauregui S, Diab H, Puertollano R. Novel Role of TRPML2 in the Regulation of the Innate Immune Response. J Immunol. 2015;195:4922-32 pubmed publisher |
- western blot; mouse; 1:2000; fig 3
| Cao Q, Zhong X, Zou Y, Murrell Lagnado R, Zhu M, Dong X. Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion. J Cell Biol. 2015;209:879-94 pubmed publisher |
- immunocytochemistry; mouse
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- immunocytochemistry; mouse
| Omari S, Waters M, Naranian T, Kim K, Perumalsamy A, Chi M, et al. Mcl-1 is a key regulator of the ovarian reserve. Cell Death Dis. 2015;6:e1755 pubmed publisher |
- immunocytochemistry; mouse; fig s3
| Ruas M, Davis L, Chen C, Morgan A, Chuang K, Walseth T, et al. Expression of Ca²âº-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells. EMBO J. 2015;34:1743-58 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- immunocytochemistry; mouse
- western blot; mouse; 1:1000
| Kett L, Stiller B, Bernath M, Tasset I, Blesa J, Jackson Lewis V, et al. α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. J Neurosci. 2015;35:5724-42 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500
- western blot; mouse; 1:1000
| Tian X, Gala U, Zhang Y, Shang W, Nagarkar Jaiswal S, di Ronza A, et al. A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. PLoS Biol. 2015;13:e1002103 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig s2c
- western blot; mouse; loading ...; fig 7d
| Rothaug M, Stroobants S, Schweizer M, Peters J, Zunke F, Allerding M, et al. LAMP-2 deficiency leads to hippocampal dysfunction but normal clearance of neuronal substrates of chaperone-mediated autophagy in a mouse model for Danon disease. Acta Neuropathol Commun. 2015;3:6 pubmed publisher |
- immunohistochemistry; mouse; fig 7
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- western blot; mouse; 1:250; fig 1
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- immunocytochemistry; mouse; fig 6
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- western blot; mouse; fig 7a
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- immunohistochemistry; mouse
- western blot; mouse
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