product summary
company name :
Developmental Studies Hybridoma Bank
product type :
antibody
product name :
Germ cell nuclear antigen 1; GCNA1
catalog :
10D9G11
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
10D9G11
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 14
Reference |
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Bristol Gould S, Kreeger P, Selkirk C, Kilen S, Cook R, Kipp J, et al. Postnatal regulation of germ cells by activin: the establishment of the initial follicle pool. Dev Biol. 2006;298:132-48 pubmed
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Maatouk D, Kellam L, Mann M, Lei H, Li E, Bartolomei M, et al. DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages. Development. 2006;133:3411-8 pubmed
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Tay J, Hodgman R, Sarkissian M, Richter J. Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003;17:1457-62 pubmed
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Tay J, Richter J. Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell. 2001;1:201-13 pubmed
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Rao D, Chang J, Kumar P, Mizukami I, Smithson G, Bradley S, et al. Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors. Mol Cell Biol. 2001;21:7796-806 pubmed
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Enders G, May J. Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev Biol. 1994;163:331-40 pubmed
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Hayward R, White J, Ead H, Baldwin A, Swanton H. A microcomputer based catheter laboratory system for analysis of coronary blood flow in man. J Biomed Eng. 1983;5:248-52 pubmed
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Goyal R, Sharma R, Mathur G, Andleigh H. Pathogenicity of different strains of vaccinia virus. Indian J Med Sci. 1969;23:247-51 pubmed
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Eddy C, Keshav K, An H, Utt E, Mejia J, Ingram L. Segmental message stabilization as a mechanism for differential expression from the Zymomonas mobilis gap operon. J Bacteriol. 1991;173:245-54 pubmed
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product information
Internal ID :
24600
Name :
10D9G11
Depositor Name :
Enders, George
Depositor Institution :
University of Kansas Medical School
Date Deposited :
12/14/16
Allow Hybridoma Distribution :
No
Cells Available (legacy) :
No
Antigen :
Germ cell nuclear antigen 1; GCNA1
Antigen Species :
Mouse
Host Species :
rat
Isotype :
RIgM
Positive Tested Species Reactivity :
Mouse,Rat
Initial Publication Pubmed ID :
8200475
Depositor Notes (Special Instructions) :
Over 100 publications have used this antibody to recognize germ cells. The protein target has recently be identified as the Gcna gene product. See PMID: 27718356
Collections :
Cell markers
Search Keywords :
Enders, George, Germ cell nuclear antigen 1; GCNA1, Mouse, RIgM, Mouse/Rat, Gcna, Gcna1, AB_2629436, Monoclonal, Cell Markers, Immunohistochemistry/Immunofluorescence/Western blot/FFPE
Antigen Molecular Weight :
80-110 kDa depending upon modification
Gene :
Gcna
Alternate Gene Name(s) :
Gcna1
Antibody Registry ID :
AB_2629436
Immunogen :
Pachytene spermatocytes
Clonality :
Monoclonal
Myeloma Strain :
SP2/N
Epitope Mapped :
No
Epitope Location or Sequence :
8-amino-acid tandem GE(P/M/S)E(S/T)EAK repeat
Epitope Map PubMed ID :
27718356
Recommended Applications :
FFPE,Immunofluorescence,Immunohistochemistry,Western Blot
Immunohistochemistry Pubmed IDs :
20423503 11702780 21655083 8200475 16930587 25781564 11604514 23766129 16887828 21655083
Immunofluorescence Pubmed IDs :
21655083 8200475 12815066
Western Blot Pubmed IDs :
8200475
FFPE Pubmed IDs :
20423503 1702780 16930587 5781564 11604514 6887828 21655083
Additional Information :
The epitope is sensitive to glutarldehyde and trypsin. RRID:AB_2629436
DSHB Growth Medium :
Iscove's
more info or order :
company information
Developmental Studies Hybridoma Bank
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