product summary
company name :
Dako
product type :
antibody
product name :
Cytokeratin 5/6
catalog :
M7237
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D5/16 B4
reactivity :
human, dogs, cat
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
more info or order :
citations: 58
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 3d
Sekino Y, Pham Q, Kobatake K, Kitano H, Ikeda K, Goto K, et al. KIFC1 Is Associated with Basal Type, Cisplatin Resistance, PD-L1 Expression and Poor Prognosis in Bladder Cancer. J Clin Med. 2021;10: pubmed publisher
  • immunohistochemistry; human; 1:100
Lindskrog S, Prip F, Lamy P, Taber A, Groeneveld C, Birkenkamp Demtroder K, et al. An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer. Nat Commun. 2021;12:2301 pubmed publisher
  • immunohistochemistry - paraffin section; cat; loading ...; fig st2
Granados Soler J, Bornemann Kolatzki K, Beck J, Brenig B, Schütz E, Betz D, et al. Analysis of Copy-Number Variations and Feline Mammary Carcinoma Survival. Sci Rep. 2020;10:1003 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 2b, 2f, 2n
Lodes N, Seidensticker K, Perniss A, Nietzer S, Oberwinkler H, May T, et al. Investigation on Ciliary Functionality of Different Airway Epithelial Cell Lines in Three-Dimensional Cell Culture. Tissue Eng Part A. 2020;26:432-440 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 6a
Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, et al. MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state. Nat Commun. 2018;9:1024 pubmed publisher
  • immunohistochemistry; human; 1:250; tbl 3
Egashira A, Morita M, Kumagai R, Taguchi K, Ueda M, Yamaguchi S, et al. Neuroendocrine carcinoma of the esophagus: Clinicopathological and immunohistochemical features of 14 cases. PLoS ONE. 2017;12:e0173501 pubmed publisher
  • immunohistochemistry; dogs; 1:50; fig S1a,S2a,S3a,S4a
Watanabe K, Chambers J, Uchida K, Nibe K, Ushio N, Horiuchi N, et al. A cutaneous mixed tumor in a dog. J Vet Med Sci. 2017;79:670-673 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; tbl 2
Masili Oku S, Bacchi C, Fernandes F, Filassi J, Baracat E, Carvalho F. The Apocrine Profile of Triple-negative Breast Carcinomas in Patients Aged 45 Years or Younger: favorable but rare features. Rev Bras Ginecol Obstet. 2016;38:512-517 pubmed
  • immunohistochemistry; human; 1:50; loading ...
Chamberland F, Maurina T, Degano Valmary S, Spicarolen T, Chaigneau L. Angiosarcoma: A Case Report of Gingival Disease with Both Palatine Tonsils Localization. Rare Tumors. 2016;8:5907 pubmed
  • immunocytochemistry; dogs; 1:100; tbl 5
Hammer S, Becker A, Rateitschak K, Mohr A, Lüder Ripoli F, Hennecke S, et al. Longitudinal Claudin Gene Expression Analyses in Canine Mammary Tissues and Thereof Derived Primary Cultures and Cell Lines. Int J Mol Sci. 2016;17: pubmed
  • immunohistochemistry - paraffin section; human; 1:25; tbl 1
Kushitani K, Amatya V, Okada Y, Katayama Y, Mawas A, Miyata Y, et al. Utility and pitfalls of immunohistochemistry in the differential diagnosis between epithelioid mesothelioma and poorly differentiated lung squamous cell carcinoma. Histopathology. 2017;70:375-384 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Liu Y, Wang K, Xing H, Zhai X, Wang L, Wang W. Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers. Oncol Lett. 2016;12:1240-1256 pubmed
  • immunohistochemistry - paraffin section; human; 1:80; tbl 3
Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
  • immunohistochemistry - paraffin section; human; 1:50; fig 4
Kim J, Jeong J, Park S, Jeong J, Ryu Y, Song S. Recurrent renal cell carcinoma manifesting as a large intrathoracic fibrotic mass: A case report. Oncol Lett. 2016;11:3835-3838 pubmed
  • immunohistochemistry; human; fig 1
Seo A, Lee H, Kim E, Jang M, Kim Y, Kim J, et al. Expression of breast cancer stem cell markers as predictors of prognosis and response to trastuzumab in HER2-positive breast cancer. Br J Cancer. 2016;114:1109-16 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; tbl 2
Liang L, Huang H, Dadhania V, Zhang J, Zhang M, Liu J. Renal cell carcinoma metastatic to the ovary or fallopian tube: a clinicopathological study of 9 cases. Hum Pathol. 2016;51:96-102 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; tbl 2
Hes O, Condom Mundo E, Peckova K, Lopez J, Martinek P, Vanecek T, et al. Biphasic Squamoid Alveolar Renal Cell Carcinoma: A Distinctive Subtype of Papillary Renal Cell Carcinoma?. Am J Surg Pathol. 2016;40:664-75 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25; loading ...
Cammas A, Lacroix Triki M, Pierredon S, Le Bras M, Iacovoni J, Teulade Fichou M, et al. hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression. Oncotarget. 2016;7:16793-805 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Kim S, Kim E, Lee H, Kim M, Yoon J, Koo J, et al. Asymptomatic Benign Papilloma Without Atypia Diagnosed at Ultrasonography-Guided 14-Gauge Core Needle Biopsy: Which Subgroup can be Managed by Observation?. Ann Surg Oncol. 2016;23:1860-6 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed publisher
  • immunohistochemistry - free floating section; human; fig 1
Bonkhoff H. Significance of prostate cancer missed on needle biopsy tools for retrieving missed cancer. Prostate. 2016;76:369-75 pubmed publisher
  • immunohistochemistry; human; 1:100
de Deus Moura R, Carvalho F, Bacchi C. Breast cancer in very young women: Clinicopathological study of 149 patients ≤25 years old. Breast. 2015;24:461-7 pubmed publisher
  • immunohistochemistry - paraffin section; human
Sanguinetti A, Santini D, Bonafè M, Taffurelli M, Avenia N. Interleukin-6 and pro inflammatory status in the breast tumor microenvironment. World J Surg Oncol. 2015;13:129 pubmed publisher
  • immunohistochemistry - paraffin section; human; tbl 2
Savci Heijink C, Halfwerk H, Hooijer G, Horlings H, Wesseling J, van de Vijver M. Retrospective analysis of metastatic behaviour of breast cancer subtypes. Breast Cancer Res Treat. 2015;150:547-57 pubmed publisher
  • immunocytochemistry; human; fig 1
Skogberg G, Lundberg V, Berglund M, Gudmundsdottir J, Telemo E, Lindgren S, et al. Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens. Immunol Cell Biol. 2015;93:727-34 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; tbl 2
Weissferdt A, Rodriguez Canales J, Liu H, Fujimoto J, Wistuba I, Moran C. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015;46:376-83 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; tbl 5
Tozbikian G, Brogi E, Kadota K, Catalano J, Akram M, Patil S, et al. Mesothelin expression in triple negative breast carcinomas correlates significantly with basal-like phenotype, distant metastases and decreased survival. PLoS ONE. 2014;9:e114900 pubmed publisher
  • immunohistochemistry; human; 1:25
Thompson L, Bauer J, Chiosea S, McHugh J, Seethala R, Miettinen M, et al. Canalicular adenoma: a clinicopathologic and immunohistochemical analysis of 67 cases with a review of the literature. Head Neck Pathol. 2015;9:181-95 pubmed publisher
  • immunohistochemistry - paraffin section; human
Jeon Y, Moon K, Park S, Chung D. Primary pulmonary myxoid sarcomas with EWSR1-CREB1 translocation might originate from primitive peribronchial mesenchymal cells undergoing (myo)fibroblastic differentiation. Virchows Arch. 2014;465:453-61 pubmed publisher
  • immunohistochemistry - paraffin section; human
Skogberg G, Lundberg V, Lindgren S, Gudmundsdottir J, Sandström K, Kämpe O, et al. Altered expression of autoimmune regulator in infant down syndrome thymus, a possible contributor to an autoimmune phenotype. J Immunol. 2014;193:2187-95 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; tbl 2
Syed B, Green A, Nolan C, Morgan D, Ellis I, Cheung K. Biological characteristics and clinical outcome of triple negative primary breast cancer in older women - comparison with their younger counterparts. PLoS ONE. 2014;9:e100573 pubmed publisher
  • immunohistochemistry; human; 1:25
Oishi N, Kondo T, Nakazawa T, Mochizuki K, Kasai K, Inoue T, et al. Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: case report and literature review. Pathol Res Pract. 2014;210:1142-5 pubmed publisher
  • immunohistochemistry; human; 1:100
Castilla M, Lopez Garcia M, Atienza M, Rosa Rosa J, Díaz Martín J, Pecero M, et al. VGLL1 expression is associated with a triple-negative basal-like phenotype in breast cancer. Endocr Relat Cancer. 2014;21:587-99 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:25
Zhang L, Frank R, Furth E, Ziober A, LiVolsi V, Zhang P. Expression and diagnostic values of calretinin and CK5/6 in cholangiocarcinoma. Exp Hematol Oncol. 2014;3:12 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Ordonez N, Sahin A. Diagnostic utility of immunohistochemistry in distinguishing between epithelioid pleural mesotheliomas and breast carcinomas: a comparative study. Hum Pathol. 2014;45:1529-40 pubmed publisher
  • immunohistochemistry; human; ready-to-use
Uchoa D, Graudenz M, Callegari Jacques S, Hartmann C, Ferreira B, Fitarelli Kiehl M, et al. Expression of cancer stem cell markers in basal and penta-negative breast carcinomas--a study of a series of triple-negative tumors. Pathol Res Pract. 2014;210:432-9 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50
Park H, Jang M, Kim E, Kim H, Lee H, Kim Y, et al. High EGFR gene copy number predicts poor outcome in triple-negative breast cancer. Mod Pathol. 2014;27:1212-22 pubmed publisher
  • immunohistochemistry; human; 1:300
Tilch E, Seidens T, Cocciardi S, Reid L, Byrne D, Simpson P, et al. Mutations in EGFR, BRAF and RAS are rare in triple-negative and basal-like breast cancers from Caucasian women. Breast Cancer Res Treat. 2014;143:385-92 pubmed publisher
  • immunohistochemistry; human; 1:50; loading ...
Yousem S. Immunohistochemical and molecular characterization of clear cell carcinoma of the lung. Hum Pathol. 2013;44:2467-74 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Yakkioui Y, Temel Y, Creytens D, Jahanshahi A, Fleischeuer R, Santegoeds R, et al. A comparison of cell-cycle markers in skull base and sacral chordomas. World Neurosurg. 2014;82:e311-8 pubmed publisher
Almeida F, Gameiro A, Correia J, Ferreira F. Histone Deacetylase Inhibitors and Microtubule Inhibitors Induce Apoptosis in Feline Luminal Mammary Carcinoma Cells. Animals (Basel). 2021;11: pubmed publisher
Brocca G, Centelleghe C, Padoan E, Stoppini R, Giudice C, Castagnaro M, et al. Case Report of a Mare Diagnosed with a Metastatic Mammary Carcinoma after the Excision of a Recurrent Intraocular Neuroepithelial Tumor. Animals (Basel). 2020;10: pubmed publisher
Oulès B, Philippeos C, Segal J, Tihy M, Vietri Rudan M, Cujba A, et al. Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis. Nat Commun. 2020;11:5067 pubmed publisher
Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
Ho H, Kao H, Yeh Y, Chou T. The importance of EGFR mutation testing in squamous cell carcinoma or non-small cell carcinoma favor squamous cell carcinoma diagnosed from small lung biopsies. Diagn Pathol. 2019;14:59 pubmed publisher
Hatanaka K, Takakuwa E, Hatanaka Y, Suzuki A, Iizuka S, Tsushima N, et al. Desmoplastic small round cell tumor of the parotid gland-report of a rare case and a review of the literature. Diagn Pathol. 2019;14:43 pubmed publisher
WALSH E, Shalaby A, O Loughlin M, Keane N, Webber M, Kerin M, et al. Outcome for triple negative breast cancer in a retrospective cohort with an emphasis on response to platinum-based neoadjuvant therapy. Breast Cancer Res Treat. 2019;174:1-13 pubmed publisher
Kriegsmann M, Kriegsmann K, Harms A, Longuespée R, Zgorzelski C, Leichsenring J, et al. Expression of HMB45, MelanA and SOX10 is rare in non-small cell lung cancer. Diagn Pathol. 2018;13:68 pubmed publisher
El Khoury V, Béland M, Schritz A, Kim S, Nazarov P, Gaboury L, et al. Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer. Br J Cancer. 2018;119:580-590 pubmed publisher
Hashmi A, Naz S, Hashmi S, Hussain Z, Irfan M, Bakar S, et al. Cytokeratin 5/6 and cytokeratin 8/18 expression in triple negative breast cancers: clinicopathologic significance in South-Asian population. BMC Res Notes. 2018;11:372 pubmed publisher
Mudduwa L, Peiris H, Gunasekara S, Abeysiriwardhana D, Liyanage N, Rayala S, et al. KIBRA; a novel biomarker predicting recurrence free survival of breast cancer patients receiving adjuvant therapy. BMC Cancer. 2018;18:589 pubmed publisher
Hashmi A, Hussain Z, Irfan M, Edhi M, Kanwal S, Faridi N, et al. Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis. BMC Res Notes. 2018;11:207 pubmed publisher
Baker S, Arlt V, Indra R, Joel M, Stiborova M, Eardley I, et al. Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers. Mol Carcinog. 2018;57:606-618 pubmed publisher
Ueno N, Kuroda H, Kurosumi M, Kozuka Y, Ito J, Kato H, et al. Clinicopathological study of a dimorphic variant of breast carcinoma. Breast Cancer. 2018;25:151-158 pubmed publisher
Veits L, Schupfner R, Hufnagel P, Penzel R, Freitag J, Strobel P, et al. KRAS, EGFR, PDGFR-?, KIT and COX-2 status in carcinoma showing thymus-like elements (CASTLE). Diagn Pathol. 2014;9:116 pubmed publisher
Wang C, Bajikar S, Jamal L, Atkins K, Janes K. A time- and matrix-dependent TGFBR3-JUND-KRT5 regulatory circuit in single breast epithelial cells and basal-like premalignancies. Nat Cell Biol. 2014;16:345-56 pubmed publisher
Sihto H, Lundin J, Lundin M, Lehtimäki T, Ristimaki A, Holli K, et al. Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study. Breast Cancer Res. 2011;13:R87 pubmed publisher
Karihtala P, Kauppila S, Soini Y, Arja Jukkola Vuorinen -. Oxidative stress and counteracting mechanisms in hormone receptor positive, triple-negative and basal-like breast carcinomas. BMC Cancer. 2011;11:262 pubmed publisher
company information
Dako
6392 Via Real
Carpinteria, CA 93013
customer.service.us@dako.com
http://www.dako.com
800-235-5763
headquarters: USA